Vincent Carey - Böcker

Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms:Curation and delivery of biological metadata for use in statistical modeling and interpretationStatistical analysis of high-throughput data, including machine learning and visualizationModeling and visualization of graphs and networksThe developers of the software, who are in many cases leading academic researchers, jointly authored chapters. All methods are illustrated with publicly available data, and a major section of the book is devoted to exposition of fully worked case studies. This book is more than a static collection of descriptive text, figures, and code examples that were run by the authors to produce the text; it is a dynamic document.Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

Early Modern Ireland: New Sources, Methods, and Perspectives offers fresh approaches and case studies that push the field of early modern Ireland, and of British and European history more generally, into unexplored directions.The centuries between 1500 and 1700 were pivotal in Ireland’s history, yet so much about this period has remained neglected until relatively recently, and a great deal has yet to be explored. Containing seventeen original and individually commissioned essays by an international and interdisciplinary group of leading and emerging scholars, this book covers a wide range of topics, including social, cultural, and political history as well as folklore, medicine, archaeology, and digital humanities, all of which are enhanced by a selection of maps, graphs, tables, and images. Urging a reevaluation of the terms and assumptions which have been used to describe Ireland’s past, and a consideration of the new directions in which the study of early modern Ireland could be taken, Early Modern Ireland: New Sources, Methods, and Perspectives is a groundbreaking collection for students and scholars studying early modern Irish history.