Vivette D. D'Agati – författare

Approximately ten percent of the world population are affected by kidney diseases, which often can only be diagnosed by renal biopsy. This practical guide offers an algorithmic, deductive approach to the interpretation of this complicated procedure, covering all technical methods used for diagnosis. This new edition includes an authoritative chapter on digital renal pathology, a topic inadequately covered in current literature. All chapters have been extensively revised in light of major advances in the understanding of the pathogenesis and clinicopathological features of renal disease. Written for practising pathologists and nephrologists, this text encompasses the entire spectrum of medical renal diseases in both pediatric and adult populations. Its numerous diagnostic algorithms provide a convenient overview and a helpful guide into the detailed text, directing the reader to major patterns of interest. Including online access to over 1000 photomicrographs and diagrams, this book is also of interest to trainees in nephrology and pathology.

The twenty-six chapters in this Atlas are organised around standardised disease entities or patterns of disease, including congenital and hereditary diseases, acquired diseases of the native kidney, and diseases of the renal allograft. Wherever possible, the authors have tried to remain consistent with the widely-recognised International Nomenclature of Disease, a joint project of the Council for International Organizations of Medical Sciences and the World Health Organization.Although this Atlas provides comprehensive coverage of the major common disease entities and their variants, it also includes many rare, but no less important, conditions. The extensive collection of images is the focal point, balanced by an informative text and selective use of illustrative tables.

Since its inception in the late 1950s, percutaneous kidney biopsy has remained the definitive gold standard for diagnosing medical renal diseases, transitioning the field from autopsy-based analysis to a dynamic, biopsy-driven discipline. This updated atlas provides a comprehensive guide to the multifaceted practice of nephropathology, which requires the systematic integration of light microscopy, immunofluorescence, and transmission electron microscopy, synthesized with clinical, serologic, radiographic, and genetic data. This volume highlights the evolution of renal pathology, emphasizing the essential collaboration between pathologists and nephrologists in defining disease entities. It reflects the latest advancements in the field, incorporating modern diagnostic techniques such as mass spectrometry for proteomic characterization, accessible genomic panels, and novel antibody markers for precise immunophenotyping. The atlas is structured to provide a clear, logical framework for diagnosis, beginning with foundational embryology and normal histopathology. Subsequent sections are organized by standardized disease patterns and entities, covering: · Congenital and hereditary diseases. · Acquired diseases of the native kidney, systematically categorized by their impact on glomerular, tubulointerstitial, and vascular compartments. · Diseases of the kidney allograft. .Adhering to the most current consensus terminology from the Renal Pathology Society and the International Society of Nephrology, this book serves as an essential resource. By balancing a comprehensive, evidence-based text with an extensive, collection of diagnostic images, this atlas offers both a vital educational tool and a practical reference for navigating the unique complexities of modern nephropathology.