This LNCS conference volume constitutes the proceedings of the 22nd International Symposium on Web and Wireless Geographical Information Systems, W2GIS 2025, in Mexico City, Mexico, held during September 8–9, 2025.The 11 full papers presented in this volume were carefully reviewed and selected from 22 submissions. They are grouped into the following topics: Advances in Geospatial Artificial Intelligence: From Pixel-level Vision to Large-Language Models; Data-driven Urban Health & Safety: Environmental Exposure, Crime, and Disease Dynamics; Location Intelligence for Urban Resources, Mobility, and Commerce.

This LNCS conference volume constitutes the proceedings of the 22nd International Symposium on Web and Wireless Geographical Information Systems, W2GIS 2025, in Mexico City, Mexico, held during September 8–9, 2025.The 11 full papers presented in this volume were carefully reviewed and selected from 22 submissions. They are grouped into the following topics: Advances in Geospatial Artificial Intelligence: From Pixel-level Vision to Large-Language Models; Data-driven Urban Health & Safety: Environmental Exposure, Crime, and Disease Dynamics; Location Intelligence for Urban Resources, Mobility, and Commerce.