Critical Issues in Transfusion Medicine and Apheresis Practice ensures the safe and effective use of blood and blood components to save lives and improve patient outcomes. It involves a multidisciplinary approach, integrating clinical practice, laboratory science, and regulatory oversight. The book addresses blood collection, testing, transfusion management and treatment of sickle cell disease (SCD), Thrombotic Thrombocytopenic Purpura (TTP), Autoimmune hemolytic anemia, and more and essential to the management of acute transfusion reactions. It is organized four parts starting with Clinically Challenging Scenarios in Transfusion Medicine to Challenging situations with case reports in Apheresis service. The book is multidisciplinary and useful for anyone who are involved in practice of transfusion medicine and for pathologists in blood bank and transfusion medicine.Presents solutions to challenges in transfusion medicine in difficult clinical situationsProvides information on blood shortage management and disaster preparation in Blood BankOffers clinical and laboratory diagnoses, therapy guidelines, and transfusion support through case reviews for both APS and HIT antibodies

This volume provides methods for the analysis of ADAMTS proteases and ADAMTS-like proteins. Chapters detail ADAMTS family members, with special attention to the exciting progress made in understanding ADAMTS13—its biology, disease mechanisms, detection, and clinical management of a potentially fatal thrombotic microangiopathy, thrombotic thrombocytopenic purpura (TTP). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, ADAMTS Proteases: Methods and Protocol is a valuable resource for any researcher hoping to contribute to the ever expanding world of ADAMTS.

Critical Issues in Transfusion Medicine and Apheresis Practice ensures the safe and effective use of blood and blood components to save lives and improve patient outcomes. It involves a multidisciplinary approach, integrating clinical practice, laboratory science, and regulatory oversight. The book addresses blood collection, testing, transfusion management and treatment of sickle cell disease (SCD), Thrombotic Thrombocytopenic Purpura (TTP), Autoimmune hemolytic anemia, and more and essential to the management of acute transfusion reactions. It is organized four parts starting with Clinically Challenging Scenarios in Transfusion Medicine to Challenging situations with case reports in Apheresis service. The book is multidisciplinary and useful for anyone who are involved in practice of transfusion medicine and for pathologists in blood bank and transfusion medicine.Presents solutions to challenges in transfusion medicine in difficult clinical situationsProvides information on blood shortage management and disaster preparation in Blood BankOffers clinical and laboratory diagnoses, therapy guidelines, and transfusion support through case reviews for both APS and HIT antibodies

This volume provides methods for the analysis of ADAMTS proteases and ADAMTS-like proteins. Chapters detail ADAMTS family members, with special attention to the exciting progress made in understanding ADAMTS13—its biology, disease mechanisms, detection, and clinical management of a potentially fatal thrombotic microangiopathy, thrombotic thrombocytopenic purpura (TTP). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, ADAMTS Proteases: Methods and Protocol is a valuable resource for any researcher hoping to contribute to the ever expanding world of ADAMTS.