Yang Zhang - Böcker

Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.Discusses cutting-edge AI and deep-learning techniques, including AlphaFold and D-I-TASSER, along with their impact on structural bioinformaticsExplores protein and RNA structure predictionConsiders the most recent advances in the field as well as more classical physics-based approachesFeatures chapter outlines, definitions, key learning objectives, and case studies throughout the book to aid comprehension

With a keen attention to how culture and elite conflict shape politics, The Great Separation upends deterministic understandings of the Chinese Cultural Revolution and the market reforms that followed. This ambitious posthumous volume by sociologist Xiaohong Xu turns the existing scholarship on China’s “neoliberalism” on its head by demonstrating that the effort to separate mass politics from economic policy had its origins well before the Reform and Opening-up era. Over the course of the Cultural Revolution, unfolding factional dynamics and interpretive struggles enabled Chairman Mao and his radical colleagues to mobilize workers to advance their own political goals while neutralizing the masses’ economic demands, symbolically separating the political from the economic. This set the stage for a more thoroughgoing depoliticization of the economy after 1989, when China faced challenges from students and workers whose economic grievances had rapidly morphed into political demands for democracy. The result was what Xu calls ordoeconomism: an ideology that valorizes economic development, rejects mass politics, and views the state as the apolitical guardian of the economy. As Xu demonstrates, while ordoeconomism may share some affinities with neoliberalism, it is a distinctively Chinese approach that must be understood on its own terms.

With a keen attention to how culture and elite conflict shape politics, The Great Separation upends deterministic understandings of the Chinese Cultural Revolution and the market reforms that followed. This ambitious posthumous volume by sociologist Xiaohong Xu turns the existing scholarship on China’s “neoliberalism” on its head by demonstrating that the effort to separate mass politics from economic policy had its origins well before the Reform and Opening-up era. Over the course of the Cultural Revolution, unfolding factional dynamics and interpretive struggles enabled Chairman Mao and his radical colleagues to mobilize workers to advance their own political goals while neutralizing the masses’ economic demands, symbolically separating the political from the economic. This set the stage for a more thoroughgoing depoliticization of the economy after 1989, when China faced challenges from students and workers whose economic grievances had rapidly morphed into political demands for democracy. The result was what Xu calls ordoeconomism: an ideology that valorizes economic development, rejects mass politics, and views the state as the apolitical guardian of the economy. As Xu demonstrates, while ordoeconomism may share some affinities with neoliberalism, it is a distinctively Chinese approach that must be understood on its own terms.

This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials. Topics covered include Raman spectroscopy of biological systems, scale dependence of the mechanical properties and microstructure of crustaceans thin films as biomimetic materials, as well as the role of molecular-level modeling. The use of nanomechanics to investigate interface thermomechanics of collagen and chitin-based biomaterials is also covered in detail.This book also:•Details spectroscope experiments as well as nanomechanic experiments•Reviews exhaustively phenomenological models and Raman spectroscopy of biological systems•Covers the latest in multiscaling for molecular models to predict lab-scale sample properties and               investigates interface thermomechanics

This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials.

color: black;">Given the rise of AI and the advent of online collaboration opportunities (e.g., social media, crowdsourcing), emerging research has started to investigate the integration of AI and human intelligence, especially in a collaborative social context.

This monograph covers the theory of finite and infinite matrices over the fields of real numbers, complex numbers and over quaternions. Emphasizing topics such as sections or truncations and their relationship to the linear operator theory on certain specific separable and sequence spaces, the authors explore techniques like conformal mapping, iterations and truncations that are used to derive precise estimates in some cases and explicit lower and upper bounds for solutions in the other cases.Most of the matrices considered in this monograph have typically special structures like being diagonally dominated or tridiagonal, possess certain sign distributions and are frequently nonsingular. Such matrices arise, for instance, from solution methods for elliptic partial differential equations. The authors focus on both theoretical and computational aspects concerning infinite linear algebraic equations, differential systems and infinite linear programming, among others. Additionally, the authors cover topics such as Bessel’s and Mathieu’s equations, viscous fluid flow in doubly connected regions, digital circuit dynamics and eigenvalues of the Laplacian.

This monograph covers the theory of finite and infinite matrices over the fields of real numbers, complex numbers and over quaternions. Emphasizing topics such as sections or truncations and their relationship to the linear operator theory on certain specific separable and sequence spaces, the authors explore techniques like conformal mapping, iterations and truncations that are used to derive precise estimates in some cases and explicit lower and upper bounds for solutions in the other cases.Most of the matrices considered in this monograph have typically special structures like being diagonally dominated or tridiagonal, possess certain sign distributions and are frequently nonsingular. Such matrices arise, for instance, from solution methods for elliptic partial differential equations. The authors focus on both theoretical and computational aspects concerning infinite linear algebraic equations, differential systems and infinite linear programming, among others. Additionally, the authors cover topics such as Bessel’s and Mathieu’s equations, viscous fluid flow in doubly connected regions, digital circuit dynamics and eigenvalues of the Laplacian.

Die Forschungsfrage des vorliegenden Buches bewegt sich im Bereich der personenbezogenen Politikforschung: Die Beziehung zwischen Angela Merkels Persönlichkeitsgrundzügen und der deutschen Außenpolitik steht im Mittelpunkt der Analysen. Der Autor deutet und interpretiert die Auswirkungen auf die deutsche Außenpolitik anhand der Beispiele Euro-, Ukraine- und Flüchtlingskrise sowie die China-Politik. Er erarbeitet vier Kategorien, denen ihre Persönlichkeitsmerkmale zugeordnet werden können. Die Analyse konzentriert sich vornehmlich auf Merkels Reaktionen auf die externen Faktoren und ihre Optionen bei der Entscheidungsfindung. Die Ergebnisse zeigen, dass Angela Merkels Persönlichkeitsmerkmale erhebliche Auswirkungen auf den Verlauf dieser bedeutenden außenpolitischen Ereignisse zeigten.

This thesis presents pioneering experimental and numerical studies on three aspects of the combustion characteristics of lean premixed syngas/air flames, namely the laminar flame speed, extinction limit and flammability limit. It illustrates a new extinction exponent concept, which enriches the combustion theory. Above all, the book provides the following: a) a series of carefully measured data and theoretical analyses to reveal the intrinsic mechanisms of the fuel composition effect on the propagation and extinction of lean syngas/air flames; b) a mixing model and correlation to predict the laminar flame speed of multi-component syngas fuels, intended for engineering computations; c) a new “extinction exponent” concept to describe the critical effects of chemical kinetics on the extinction of lean premixed syngas/air flames; and d) the effects and mechanism of the dilution of incombustible components on lean premixed syngas/air flames and the preferential importance among the thermal, chemical and diffusion effects.

This timely book documents marvelous brachiopod fossils from the Palaeozoic-Mesozoic transition of South China. Numerous beautiful pictures and detailed descriptions (specifically the measurements of body size) of brachiopod species are presented. Systematic discussion on the evolution of brachiopod biodiversity and morphological features across the critical interval is not only extremely important for paleontologists to understand the marine ecosystem evolution from the Palaeozoic to the Mesozoic, but also attractive for students who need to know about the end-Permian mass extinction.The book distinguishes itself from other studies by its detailed study of the taxonomy, biodiversity and paleoecology of Permian-Triassic brachiopods from different palaeogeographic facies, especially from the deep-water environment in South China. The book also offers a unique study of the response of morphological features of brachiopods to palaeoenvironmental changes, providing insights for the process of Permian-Triassic crisis.