Yufang Shi – författare

Proceedings of an international symposium held in Shanghai, China, September 8-12, 1996

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner, H. Robert Horvitz, and John E. Sulston for their seminal discoveries concerning "genetic regulation of organ development and programmed cell death." This clearly marked the prime importance of understanding the molecular mechanisms controlling cell death. The 1 st International Symposium on Programmed Cell Death was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. A number of key issues in apoptosis were discussed at the meeting, and progress in major areas of apopto­ sis research was summarized by expert participants at the meeting and published by Plenum Publishing Corporation as a book entitled Programmed Cell Death. In the last six years, we have witnessed a real explosion in our knowledge on how cells undergo apoptosis, thereby participating in various developmental and pathophysiological processes. At this ever­ exciting time, we organized the 2nd International Symposium on Programmed Cell Death.

This volume presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. Top scientists from around the world wrote on current progresses to help establish and/or strengthen communications between scientists from the West and those in Asia.

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner, H. Robert Horvitz, and John E. Sulston for their seminal discoveries concerning "genetic regulation of organ development and programmed cell death." This clearly marked the prime importance of understanding the molecular mechanisms controlling cell death. The 1 st International Symposium on Programmed Cell Death was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. A number of key issues in apoptosis were discussed at the meeting, and progress in major areas of apopto­ sis research was summarized by expert participants at the meeting and published by Plenum Publishing Corporation as a book entitled Programmed Cell Death. In the last six years, we have witnessed a real explosion in our knowledge on how cells undergo apoptosis, thereby participating in various developmental and pathophysiological processes. At this ever­ exciting time, we organized the 2nd International Symposium on Programmed Cell Death.

This volume contains papers that were presented and discussed at The 1996 Interna­ tional Symposium on Programmed Cell Death, which was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. Apoptosis has attracted great attention in the past several years. This is reflected in part by the exponential increase in the number of papers published on the subject. While several major scientific conferences have been held in recent years, this meeting repre­ sents the first major international scientific meeting on programmed cell death held in Asia, where fast economic growth promises a bright future for both basic and applied re­ search in biomedical sciences. We organized the meeting with the belief that such a gath­ ering would foster a closer interaction between scientists from the West and those in Asia. Research on programmed cell death has expanded so extensively that no one meet­ ing can cover all the important subjects related to apoptosis. The Shanghai meeting fo­ cused on several key areas ranging from well-established ones, such as cell death in the immune system, to emerging ones, such as the role ofECM in regUlating cell fate. Specifi­ cally, the subjects presented and discussed included programmed cell death during devel­ opment, the regulation and biochemical mechanisms of lymphocyte apoptosis, the involvement of extracellular matrix and its remodeling in programmed cell death, genes that cause or prevent cell death, and the application of apoptosis toward cancer therapy.