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Materials for Ultra-Supercritical and Advanced Ultra-Supercritical Power Plants provides researchers in academia and industry with an essential overview of the stronger high-temperature materials required for key process components, such as membrane wall tubes, high-pressure steam piping and headers, superheater tubes, forged rotors, cast components, and bolting and blading for steam turbines in USC power plants. Advanced materials for future advanced ultra-supercritical power plants, such as superalloys, new martensitic and austenitic steels, are also addressed. Chapters on international research directions complete the volume.
The transition from conventional subcritical to supercritical thermal power plants greatly increased power generation efficiency. Now the introductions of the ultra-supercritical (USC) and, in the near future, advanced ultra-supercritical (A-USC) designs are further efforts to reduce fossil fuel consumption in power plants and the associated carbon dioxide emissions. The higher operating temperatures and pressures found in these new plant types, however, necessitate the use of advanced materials.
Provides researchers in academia and industry with an authoritative and systematic overview of the stronger high-temperature materials required for both ultra-supercritical and advanced ultra-supercritical power plants Covers materials for critical components in ultra-supercritical power plants, such as boilers, rotors, and turbine blades Addresses advanced materials for future advanced ultra-supercritical power plants, such as superalloys, new martensitic and austenitic steels Includes chapters on technologies for welding technologies854 kr
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Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more.
Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry.
For the first time, the fundamental scientific principles of biopharmaceuticals and small molecule chemotherapeutics are discussed side-by-side at a basic level Edited by three senior scientists with over 100 years of experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development196 kr
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