Atlas of Anatomic Pathology – serie

The spleen is an organ which has diverse functions including immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the normal and pathologic conditions that afflict the spleen. This extraordinary collection of high quality digital images will materially aid in continuing efforts to recognize, understand, and accurately interpret the gross and light microscopic findings in spleens.

Bone is a living tissue prone to develop a diverse array of inflammatory, metabolic, genetic, reactive, circulatory and neoplastic abnormalities.  The Atlas of Bone Pathology describes and selectively illustrates the normal and pathologic conditions that afflict human bone, focusing heavily on tumor and tumor-like conditions of bone and their non-neoplastic mimics.  Supplemented with radiographic and special study images, this extraordinary collection of high quality digital images aid continuing efforts to recognize, understand, and accurately interpret the light microscopic findings in bone specimens. Authored by nationally and internationally recognized pathologists, The Atlas of Bone Pathology is a concise and useful resource for both novice and seasoned pathologists alike.

Soft tissue tumors are a large and heterogeneous group of tumors and pseudotumors with a spectrum of behavior from benign to frankly malignant.  This Atlas of Soft Tissue Tumor Pathology provides an overview of reactive, pseudoneoplastic, benign and intermediate neoplasms, sarcomas and related conditions arising in subcutaneous and deep soft tissues. Emphasis is placed on microscopic appearances with correlation with gross diagnostic findings where relevant. In addition, the immunohistochemical and molecular genetic features of the major soft tissue tumor subtypes are presented. This compendium of soft tissue tumors illustrates the vast majority of diseases you are likely to encounter in surgical pathology.

The kidney is an organ with complex organogenesis susceptible to numerous misadventures in development and is exposed to a diverse array of insults of hematogenous and lower urinary tract origin. This Atlas of Medical Renal Pathology provides an overview of the development, macroscopic and microscopic features of the normal kidney. This is followed by a comprehensive survey of developmental and cystic kidney diseases, vascular diseases and tubulointerstitial diseases. An emphasis is placed on gross diagnostic findings with detailed histological correlates. In addition, the histological, immunofluorescent, immunohistochemical and ultrastructural features of the major glomerular diseases and renal transplantation pathology are presented. This compendium of non-neoplastic kidney diseases illustrates the vast majority diseases you are likely to encounter in surgical and autopsy pathology.

Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases.Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.

Atlas of Esophagus and Stomach Pathology provides an image-based resource for those studying normal histology of the upper gastrointestinal tract, as well as the microscopic manifestations of developmental abnormalities, toxic insults, infectious diseases, inflammatory and autoimmune conditions, and neoplasia in the esophagus and stomach. Because modern gastrointestinal pathology practice centers on specimens obtained during endoscopic examination, the atlas focuses on biopsy pathology, providing “real-world” microscopic images and ancillary diagnostic studies for most commonly-encountered abnormalities and diseases affecting these two organs. The book is supplemented with endoscopic and special study images. Authored by nationally and internationally recognized pathologists, Atlas of Esophagus and Stomach Pathology is a valuable tool for both pathologists-in-training seeking to make “new acquaintances”, and practicing surgical pathologists in need of a quick visual reference in recalling “old friends” in the world of diagnostic gastrointestinal pathology.

The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological  patterns.  Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information.Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.

Atlas of Endocrine Pathology

The mediastinum is a virtual compartment in the chest cavity that is the seat of several vital organs and structures that can be involved in a variety of pathologic processes, including congenital and developmental abnormalities, inflammatory conditions, and benign and malignant neoplasms. The Atlas of Mediastinal Pathology provides a pictorial survey of the major disease processes that can affect this anatomic compartment, including congenital and acquired cysts, benign hamartomatous processes, inflammatory processes involving the mediastinum, and benign and malignant neoplasms. The latter includes tumors of the thymus (thymoma and thymic carcinoma), neuroendocrine neoplasms, germ cell tumors, mesenchymal neoplasms, and hematolymphoid malignancies. The use of ancillary diagnostic methods is illustrated, where appropriate, providing assistance for pathologists in arriving at the correct diagnosis.

The kidney is an organ with complex organogenesis susceptible to numerous misadventures in development and is exposed to a diverse array of insults of hematogenous and lower urinary tract origin. This Atlas of Medical Renal Pathology provides an overview of the development, macroscopic and microscopic features of the normal kidney. This is followed by a comprehensive survey of developmental and cystic kidney diseases, vascular diseases and tubulointerstitial diseases. An emphasis is placed on gross diagnostic findings with detailed histological correlates. In addition, the histological, immunofluorescent, immunohistochemical and ultrastructural features of the major glomerular diseases and renal transplantation pathology are presented. This compendium of non-neoplastic kidney diseases illustrates the vast majority diseases you are likely to encounter in surgical and autopsy pathology.

Atlas of Esophagus and Stomach Pathology provides an image-based resource for those studying normal histology of the upper gastrointestinal tract, as well as the microscopic manifestations of developmental abnormalities, toxic insults, infectious diseases, inflammatory and autoimmune conditions, and neoplasia in the esophagus and stomach. Because modern gastrointestinal pathology practice centers on specimens obtained during endoscopic examination, the atlas focuses on biopsy pathology, providing “real-world” microscopic images and ancillary diagnostic studies for most commonly-encountered abnormalities and diseases affecting these two organs. The book is supplemented with endoscopic and special study images. Authored by nationally and internationally recognized pathologists, Atlas of Esophagus and Stomach Pathology is a valuable tool for both pathologists-in-training seeking to make “new acquaintances”, and practicing surgical pathologists in need of a quick visual reference in recalling “old friends” in the world of diagnostic gastrointestinal pathology.

Bone is a living tissue prone to develop a diverse array of inflammatory, metabolic, genetic, reactive, circulatory and neoplastic abnormalities.  The Atlas of Bone Pathology describes and selectively illustrates the normal and pathologic conditions that afflict human bone, focusing heavily on tumor and tumor-like conditions of bone and their non-neoplastic mimics.  Supplemented with radiographic and special study images, this extraordinary collection of high quality digital images aid continuing efforts to recognize, understand, and accurately interpret the light microscopic findings in bone specimens. Authored by nationally and internationally recognized pathologists, The Atlas of Bone Pathology is a concise and useful resource for both novice and seasoned pathologists alike.

The mediastinum is a virtual compartment in the chest cavity that is the seat of several vital organs and structures that can be involved in a variety of pathologic processes, including congenital and developmental abnormalities, inflammatory conditions, and benign and malignant neoplasms. The Atlas of Mediastinal Pathology provides a pictorial survey of the major disease processes that can affect this anatomic compartment, including congenital and acquired cysts, benign hamartomatous processes, inflammatory processes involving the mediastinum, and benign and malignant neoplasms. The latter includes tumors of the thymus (thymoma and thymic carcinoma), neuroendocrine neoplasms, germ cell tumors, mesenchymal neoplasms, and hematolymphoid malignancies. The use of ancillary diagnostic methods is illustrated, where appropriate, providing assistance for pathologists in arriving at the correct diagnosis.

The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological  patterns.  Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information.Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.

Soft tissue tumors are a large and heterogeneous group of tumors and pseudotumors with a spectrum of behavior from benign to frankly malignant.  This Atlas of Soft Tissue Tumor Pathology provides an overview of reactive, pseudoneoplastic, benign and intermediate neoplasms, sarcomas and related conditions arising in subcutaneous and deep soft tissues. Emphasis is placed on microscopic appearances with correlation with gross diagnostic findings where relevant. In addition, the immunohistochemical and molecular genetic features of the major soft tissue tumor subtypes are presented. This compendium of soft tissue tumors illustrates the vast majority of diseases you are likely to encounter in surgical pathology.

The spleen is an organ which has diverse functions including immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the normal and pathologic conditions that afflict the spleen. This extraordinary collection of high quality digital images will materially aid in continuing efforts to recognize, understand, and accurately interpret the gross and light microscopic findings in spleens.

Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases.Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.

Atlas of Endocrine Pathology provides a comprehensive compendium of photomicrographs of common and uncommon entities in endocrine pathology. The volume includes histologic features of normal features, reactive conditions, hyperplasia and tumors. The most helpful diagnostic features are illustrated to provide direction and clues to the diagnosis of endocrine tumors. Furthermore, photomicrographs highlight the most pertinent diagnostic features in problematic diagnoses in endocrine pathology.Authored by a nationally and internationally recognized pathologist, Atlas of Endocrine Pathology is an important learning tool for those becoming familiar with the diverse entities encountered in endocrine pathology and a valuable reference for practicing pathologists faced with challenging diagnoses in endocrine pathology.

This atlas illustrates the range of breast lesions with detailed correlation of gross and microscopic features. Where relevant, radiological images are incorporated.  A description of normal, developmental and physiological breast morphology will serve as introduction to the main content of this atlas. Classification of tumors is based on the latest World Health Organization Classification of Tumors of the Breast, 4th edition, 2012. As immunohistochemistry is a key adjunctive tool in the workup of breast lesions as well as used in prognostic evaluation of breast cancers, appropriate examples are interspersed among the lesions where pertinent.

This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis.  After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body.  This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders.  The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms.  The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification.  This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.​

This atlas illustrates the range of breast lesions with detailed correlation of gross and microscopic features. Where relevant, radiological images are incorporated.  A description of normal, developmental and physiological breast morphology will serve as introduction to the main content of this atlas. Classification of tumors is based on the latest World Health Organization Classification of Tumors of the Breast, 4th edition, 2012. As immunohistochemistry is a key adjunctive tool in the workup of breast lesions as well as used in prognostic evaluation of breast cancers, appropriate examples are interspersed among the lesions where pertinent.

This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis.  After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body.  This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders.  The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms.  The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification.  This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.​

Atlas of Lung Pathology offers a comprehensive survey of common and uncommon conditions likely to be encountered in a wide range of practices.  It begins with a review of normal macroscopic and microscopic lung anatomy followed by practical tips on how to handle the most common specimens received in pathology practice.  Non-neoplastic conditions are segregated into logical categories intended to make them easily accessible to quickly offer solutions for diagnostic problems encountered in daily practice.  Each illustration was carefully chosen using images drawn from experienced contributors familiar with the challenges of diagnostic pulmonary pathology.​

Atlas of Lung Pathology offers a comprehensive survey of common and uncommon conditions likely to be encountered in a wide range of practices.  It begins with a review of normal macroscopic and microscopic lung anatomy followed by practical tips on how to handle the most common specimens received in pathology practice.  Non-neoplastic conditions are segregated into logical categories intended to make them easily accessible to quickly offer solutions for diagnostic problems encountered in daily practice.  Each illustration was carefully chosen using images drawn from experienced contributors familiar with the challenges of diagnostic pulmonary pathology.​

Cytology is a unique subspecialty in anatomic pathology, and plays a critical role in the diagnosis of a variety of benign and malignant lesions by using minimally invasive procedures, such as fine needle aspiration, brushing, washing and lavage.  Cytology not only provides an accurate diagnosis of the lesion based on the cytomorphological evaluation at cellular level, but also provides material for molecular characterization of a tumor for targeted therapy.  In the era of personalized medicine, cytology has continued to grow and evolve as an important diagnostic tool.  For example, some types of procedures are routinely used, diagnostic criteria have become more refined, and certain terminology has been changed based on current WHO classifications.  Therefore, it is necessary to update our knowledge and terminology in cytology.  In this volume, we have retained the quality and the clarity of the series, and like the other volumes, this volume aims to be concise and comprehensive yet clinically relevant to daily practice.  Although this volume is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practice approach to diagnose benign and malignant lesions.  In each chapter, the key cytomorphological feature and main differential diagnoses of the lesion are summarized in a concise table.  Images in each chapter are instructive and clearly represent findings.  Where necessary, we have also illustrated the important ancillary tests, such as flow cytometry, immunohistochemistry and molecular analysis, which are crucial for an accurate diagnosis and targeted therapy.  The updated knowledge, including key cytomorphological features, current terminology and molecular diagnostic tests, is the highlight of this volume.

Intestinal neoplasia comprises a large part of a surgical pathologist’s workload. Pathologists play a key role not only in the classification of malignancies but also in assisting screening programs, identifying incidental neoplasms, and guiding treatment by providing essential prognostic features for individual entities. A large variety of neoplasms affect the intestines, and there is ongoing discovery of new entities and prognostic features for known diseases. Pathologists and trainees should have a solid understanding of key morphologic features, pitfalls, and differential diagnoses. Importantly, pathologists should recognize and communicate features that help their clinical colleagues in making treatment decisions, with the ultimate goal of benefiting the patient first and foremost.The first volume of the Atlas of Intestinal Pathology provides a comprehensive yet concise, primarily visual review of intestinal neoplasms.  It also serves asa useful resource primarily for pathologists and trainees in pathology by providing a concise yet comprehensive summary of morphology of intestinal neoplasia. Clinical practitioners and trainees also benefit from an understanding of the pathologic correlates to the diseases they manage.

This Atlas of Uterine Pathology is comprehensive overview of the major pathologic processes that may be encountered in the uterine corpus and cervix. Each section is lavishly illustrated and covers normal histology as well as neoplastic and non-neoplastic diseases. Emphasis is placed on presenting the full morphologic and immunophenotypic spectrum of entities, including classical and variant pathology, in a manner that maximizes the utility of the information in routine diagnostic practice.

This Atlas of Uterine Pathology is comprehensive overview of the major pathologic processes that may be encountered in the uterine corpus and cervix. Each section is lavishly illustrated and covers normal histology as well as neoplastic and non-neoplastic diseases. Emphasis is placed on presenting the full morphologic and immunophenotypic spectrum of entities, including classical and variant pathology, in a manner that maximizes the utility of the information in routine diagnostic practice.

This book is a unique surgical pathology grossing atlas, comprised of a collection of photos of various anatomic specimens frequently encountered in routine and frozen surgical pathology practice, including various organ systems. The photos in this atlas have been collected over many years of practicing surgical pathology in one of the largest medical centers in the world, and include emphasis on important anatomic landmarks and explanations on how to properly orient, section and sample anatomic specimens. The use of actual gross images allows readers to more readily apply the grossing tips to actual specimens that they encounter at the grossing bench. Each chapter is arranged by organ system and includes essential tips for grossing each specimen and sample dictations with all the essential elements that must be addressed for proper assessment of each organ specimen.Written by expert pathologists, Atlas of Surgical Pathology Grossing is an excellent resourcefor pathologists, medical and pathology assistant students, residents, both in surgery and pathology, and pathology assistants.