Focus on Structural Biology – serie
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21 produkter
Perspectives on Solid State NMR in Biology
Av S.R. Kiihne, H.J.M. de Groot
Inbunden, 2001
1643 kr
Lägg i varukorg
Solid state NMR is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings volume - from a recent international workshop - captures an image of the developments and …
Mass Spectrometry and Genomic Analysis
Av J.N. Housby
Inbunden, 2001
1098 kr
Lägg i varukorg
The human genome project is set to revolutionize health care and medicine. The genetic make up of each individual gives clues as to the genetic factors that predispose one to a particular genetic disease. Single Nucleotide Polymorphisms (SNPs), single base changes in the nucleotide DNA sequence of …
Guide to Protein Isolation
Av C. Dennison
Inbunden, 2003
1098 kr
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It is a truism of science that the more fundamental the subject, the more universally applicable it is. Neverthelens, it is important to strike a level of "fundamentalness" appropriate to the task in hand. For example, an in-depth study of the mechanics of motor cars would tell one nothing about …
Fundamentals of Protein NMR Spectroscopy
Av Gordon S. Rule, T. Kevin Hitchens
Inbunden, 2005
1425 kr
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NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to …
NMR in Biological Systems
From Molecules to Human
Av K.V.R. Chary, Girjesh Govil
Inbunden, 2008
1130 kr
Lägg i varukorg
During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book caters to the needs of: (i) graduate students who mostly learn such techniques from senior post-docs in the laboratory; (ii) …
Protein folding and misfolding: neurodegenerative diseases
Inbunden, 2009
1691 kr
Lägg i varukorg
It was twenty ?ve years ago this year that for the ?rst time a protein under- ing a form of human cerebral amyloidosis, the Icelandic-type hereditary cerebral haemorrhage was identi?ed. This, together with the recognition that an amino acid substitution can transform the wild type cystatin C into a …
Cryo-Electron Tomography
Structural Biology in situ
Av Friedrich Förster, Ariane Briegel
Inbunden, 2024
2478 kr
Lägg i varukorg
This book presents key aspects and recent developments of cryogenic sample electron tomography (cryo-ET) methodology, authored by leading experts in the field. Understanding structure and function of biomolecules in the context of cells is a new frontier in cellular and structural biology. To …
Cryo-Electron Tomography
Structural Biology in situ
Av Friedrich Förster, Ariane Briegel
Häftad, 2025
2478 kr
Lägg i varukorg
This book presents key aspects and recent developments of cryogenic sample electron tomography (cryo-ET) methodology, authored by leading experts in the field. Understanding structure and function of biomolecules in the context of cells is a new frontier in cellular and structural biology. To …
Perspectives on Solid State NMR in Biology
Av S.R. Kiihne, H.J.M. de Groot
Häftad, 2010
1643 kr
Lägg i varukorg
Solid state NMR is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings -; from a recent international workshop - captures an image of the latest developments and …
Guide to Protein Isolation
Av C. Dennison
Häftad, 2010
1098 kr
Lägg i varukorg
It is a truism of science that the more fundamental the subject, the more universally applicable it is. Neverthelens, it is important to strike a level of "fundamentalness" appropriate to the task in hand. For example, an in-depth study of the mechanics of motor cars would tell one nothing about …
Fundamentals of Protein NMR Spectroscopy
Av Gordon S. Rule, T. Kevin Hitchens
Häftad, 2010
1467 kr
Lägg i varukorg
NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to …
NMR in Biological Systems
From Molecules to Human
Av K.V.R. Chary, Girjesh Govil
Häftad, 2010
1128 kr
Lägg i varukorg
During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book caters to the needs of: (i) graduate students who mostly learn such techniques from senior post-docs in the laboratory; (ii) …
Protein folding and misfolding: neurodegenerative diseases
Häftad, 2010
1692 kr
Lägg i varukorg
It was twenty ?ve years ago this year that for the ?rst time a protein under- ing a form of human cerebral amyloidosis, the Icelandic-type hereditary cerebral haemorrhage was identi?ed. This, together with the recognition that an amino acid substitution can transform the wild type cystatin C into a …
Identification of Ligand Binding Site and Protein-Protein Interaction Area
Inbunden, 2012
1692 kr
Lägg i varukorg
This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It should be noted that there are many other theoretical studies devoted to predicting the activity of specific proteins and that useful protein data can be found in …
Mass Spectrometry and Genomic Analysis
Av J.N. Housby
Häftad, 2013
1128 kr
Lägg i varukorg
76 2. Short Oligonucleotide Mass Analysis 76 2. 1. Method Outline 76 2. 2. Design of PCR Primers and Fragments for Analysis 78 2. 3. Typical PCR Reaction Conditions 79 3. Electrospray Ionisation Mass Spectrometry 79 Formation of Ions 3. 1. 79 3. 2. Tandem Mass Spectrometry 79 3. 3. Typical ESI-MS …
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
Mechanism Underlying the Resistance to Prion Diseases
Av Jiapu Zhang
Inbunden, 2015
1692 kr
Lägg i varukorg
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased …
Guide to Biomolecular Simulations
Av Oren M. Becker, Martin Karplus
Häftad, 2016
1062 kr
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Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. …
Identification of Ligand Binding Site and Protein-Protein Interaction Area
Häftad, 2014
1692 kr
Lägg i varukorg
This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It should be noted that there are many other theoretical studies devoted to predicting the activity of specific proteins and that useful protein data can be found in …
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
Mechanism Underlying the Resistance to Prion Diseases
Av Jiapu Zhang
Häftad, 2016
1692 kr
Lägg i varukorg
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased …
Molecular Dynamics Analyses of Prion Protein Structures
The Resistance to Prion Diseases Down Under
Av Jiapu Zhang
Inbunden, 2018
1643 kr
Lägg i varukorg
Unlike bacteria and viruses, which are based on DNA and RNA, prions are unique as disease-causing agents since they are misfolded proteins. Prion diseases are called "protein structural conformational” diseases. This monograph is the book on molecular dynamics (MD) simulations nearly for all the …
Molecular Dynamics Analyses of Prion Protein Structures
The Resistance to Prion Diseases Down Under
Av Jiapu Zhang
Häftad, 2018
1559 kr
Lägg i varukorg
Unlike bacteria and viruses, which are based on DNA and RNA, prions are unique as disease-causing agents since they are misfolded proteins. Prion diseases are called "protein structural conformational” diseases. This monograph is the book on molecular dynamics (MD) simulations nearly for all the …
