Human Molecular Genetics – serie
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This volume of the Human Molecular Genetics series covers such genotype-phenotype correlations as clinical and environmental aspects, gene structure, expression, and mutation. Also discussed are models of certain diseases and future prospects for treatment and prevention. This book provides the reader with a basic overview of the physical expression of genetic disease before discussing in detail the most recent research and therapeutic developments.
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This volume critically examines current methods for detecting and identifying mutagens in the environment. It describes the molecular mechanisms of mutagenesis, and assesses the involvement of mutagens in cancer and inherited disease. Full details are provided on all the major in vivo and in vitro methods of mutagenicity testing, including fluorescence in situ hybridization, the use of genetically engineered cells, and transgene technology.