Valerio Cozzani (1968) received his Ph.D. in Chemical Engineering from the University of Pisa (Italy) in 1996. During the Ph.D. he spent an year at the Industrial Hazard Unit (IPSC) of the Ispra European Community Joint Research Centre. After the Ph.D. he joined the National Research Group on Chemical and Environmental Risk of the Italian National Council of Research. Formerly lecturer at the University of Pisa, he is now professor at the Department of Civil, Chemical, Environmental and Materials Engineering of Bologna University, where he leads the Laboratory on Industrial Safety and Environmental Sustainability. He is Director of the academic graduate and undergraduate programs in Chemical Engineering an lectures on unit operations, design, loss prevention and risk assessment. He coordinated several joint university-industry training projects. His main research experience is in the field of safety of chemical processes and of environmental and energy technologies. The specific subjects afforded in his research activity are, among others, the development of innovative methodologies and models for hazard and risk analysis, the development of models for equipment damage and the implementation of procedures for the quantitative assessment of accidental scenarios triggered by external hazard factors. He has a wide experience in leading national and international research projects funded either by public organizations or by private companies. He coordinates the Italian working party on safety in the chemical and process industry (CISAP) and is Member of the Working Party of Loss Prevention (EFCE). He received the Trevor Kletz Merit Award 2015 for outstanding contributions to the field of Process Safety. He serves as Associate Editor of Safety Science and is a member of the Editorial Boards of the Journal of Hazardous Materials and of the Journal of Loss Prevention in the Process Industry. Genserik Reniers works at the Universita di Bologna, DICAM in the Laboratory for Industrial Safety and Environmental Sustainability, Bologna in Italy.

• 1. The importance of innovation and new findings in domino effects researchPart 1. Dynamic risk assessment for domino effects2. Dynamic risk assessment for dealing with domino effects3. A Bayesian Network based methodology for domino effect assessment4. A Petri-net based methodology for domino effect assessment5. Markov chain-based methodologies for domino effect assessmentPart 2. Security innovations for dealing with domino effects6. Using Graph theory for managing domino effects from a security viewpoint7. Using Game Theory for managing domino effects from a security viewpoint8. Stand-off distances for domino effect caused by intentional acts9. Vulnerability assessment of chemical plants to intentional acts10. Economic model for tackling intentional domino effects in a chemical facilityPart 3. Mitigation and Emergency Management of Domino Scenarios11. Mitigation barriers for domino effect12. Assessment of safety barriers and mitigation of domino scenarios13. Mitigation of fire-induced domino scenarios14. The influence of harsh environment in the management of safety barriers15. The emergency planning matrix for safety-related domino effects16. The emergency planning matrix for security-related domino effects17. Conclusions Glossary List of Acronyms

Valerio Cozzani (1968) received his Ph.D. in Chemical Engineering from the University of Pisa (Italy) in 1996. During the Ph.D. he spent an year at the Industrial Hazard Unit (IPSC) of the Ispra European Community Joint Research Centre. After the Ph.D. he joined the National Research Group on Chemical and Environmental Risk of the Italian National Council of Research. Formerly lecturer at the University of Pisa, he is now professor at the Department of Civil, Chemical, Environmental and Materials Engineering of Bologna University, where he leads the Laboratory on Industrial Safety and Environmental Sustainability. He is Director of the academic graduate and undergraduate programs in Chemical Engineering an lectures on unit operations, design, loss prevention and risk assessment. He coordinated several joint university-industry training projects. His main research experience is in the field of safety of chemical processes and of environmental and energy technologies. The specific subjects afforded in his research activity are, among others, the development of innovative methodologies and models for hazard and risk analysis, the development of models for equipment damage and the implementation of procedures for the quantitative assessment of accidental scenarios triggered by external hazard factors. He has a wide experience in leading national and international research projects funded either by public organizations or by private companies. He coordinates the Italian working party on safety in the chemical and process industry (CISAP) and is Member of the Working Party of Loss Prevention (EFCE). He received the Trevor Kletz Merit Award 2015 for outstanding contributions to the field of Process Safety. He serves as Associate Editor of Safety Science and is a member of the Editorial Boards of the Journal of Hazardous Materials and of the Journal of Loss Prevention in the Process Industry. Genserik Reniers works at the Universita di Bologna, DICAM in the Laboratory for Industrial Safety and Environmental Sustainability, Bologna in Italy.

• 1. The importance of innovation and new findings in domino effects researchPart 1. Dynamic risk assessment for domino effects2. Dynamic risk assessment for dealing with domino effects3. A Bayesian Network based methodology for domino effect assessment4. A Petri-net based methodology for domino effect assessment5. Markov chain-based methodologies for domino effect assessmentPart 2. Security innovations for dealing with domino effects6. Using Graph theory for managing domino effects from a security viewpoint7. Using Game Theory for managing domino effects from a security viewpoint8. Stand-off distances for domino effect caused by intentional acts9. Vulnerability assessment of chemical plants to intentional acts10. Economic model for tackling intentional domino effects in a chemical facilityPart 3. Mitigation and Emergency Management of Domino Scenarios11. Mitigation barriers for domino effect12. Assessment of safety barriers and mitigation of domino scenarios13. Mitigation of fire-induced domino scenarios14. The influence of harsh environment in the management of safety barriers15. The emergency planning matrix for safety-related domino effects16. The emergency planning matrix for security-related domino effects17. Conclusions Glossary List of Acronyms

Valerio Cozzani (1968) received his Ph.D. in Chemical Engineering from the University of Pisa (Italy) in 1996. During the Ph.D. he spent an year at the Industrial Hazard Unit (IPSC) of the Ispra European Community Joint Research Centre. After the Ph.D. he joined the National Research Group on Chemical and Environmental Risk of the Italian National Council of Research. Formerly lecturer at the University of Pisa, he is now professor at the Department of Civil, Chemical, Environmental and Materials Engineering of Bologna University, where he leads the Laboratory on Industrial Safety and Environmental Sustainability. He is Director of the academic graduate and undergraduate programs in Chemical Engineering an lectures on unit operations, design, loss prevention and risk assessment. He coordinated several joint university-industry training projects. His main research experience is in the field of safety of chemical processes and of environmental and energy technologies. The specific subjects afforded in his research activity are, among others, the development of innovative methodologies and models for hazard and risk analysis, the development of models for equipment damage and the implementation of procedures for the quantitative assessment of accidental scenarios triggered by external hazard factors. He has a wide experience in leading national and international research projects funded either by public organizations or by private companies. He coordinates the Italian working party on safety in the chemical and process industry (CISAP) and is Member of the Working Party of Loss Prevention (EFCE). He received the Trevor Kletz Merit Award 2015 for outstanding contributions to the field of Process Safety. He serves as Associate Editor of Safety Science and is a member of the Editorial Boards of the Journal of Hazardous Materials and of the Journal of Loss Prevention in the Process Industry. Genserik Reniers works at the Universita di Bologna, DICAM in the Laboratory for Industrial Safety and Environmental Sustainability, Bologna in Italy.

• 1. The importance of innovation and new findings in domino effects researchPart 1. Dynamic risk assessment for domino effects2. Dynamic risk assessment for dealing with domino effects3. A Bayesian Network based methodology for domino effect assessment4. A Petri-net based methodology for domino effect assessment5. Markov chain-based methodologies for domino effect assessmentPart 2. Security innovations for dealing with domino effects6. Using Graph theory for managing domino effects from a security viewpoint7. Using Game Theory for managing domino effects from a security viewpoint8. Stand-off distances for domino effect caused by intentional acts9. Vulnerability assessment of chemical plants to intentional acts10. Economic model for tackling intentional domino effects in a chemical facilityPart 3. Mitigation and Emergency Management of Domino Scenarios11. Mitigation barriers for domino effect12. Assessment of safety barriers and mitigation of domino scenarios13. Mitigation of fire-induced domino scenarios14. The influence of harsh environment in the management of safety barriers15. The emergency planning matrix for safety-related domino effects16. The emergency planning matrix for security-related domino effects17. Conclusions Glossary List of Acronyms