DNA Repair and Replication

DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters.

Selected Contents:

• Base Excision Repair
• Eukaryotic DNA Mismatch Repair
• Double Strand Break Repair
• Functions of DNA Polymerases
• Somatic Hypermutation: A Mutational Panacea