Protein Lipidation

Inbunden, Engelska, 2000

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Beskrivning

This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented.

The enzymatic mechanisms of protein lipidation
Three-dimensional structures of protein farnesytransferase, protein geranylgeranytransferase II, and n-myristoryltransferase

Produktinformation

Utgivningsdatum:2000-10-19
Mått:152 x 229 x undefined mm
Vikt:600 g
Format:Inbunden
Språk:Engelska
Serie:The Enzymes
Antal sidor:322
Upplaga:3
Förlag:Elsevier Science
ISBN:9780121227227

Utforska kategorier

Biokemi inom Naturvetenskap och teknik

Mer om författaren

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.

Innehållsförteckning

Mechanism of Catalysis by Protein FarnesyltransferaseStructure of Protein FarnesyltransferaseMutational Analyses of Protein FarnesyltransferaseFarnesyltransferase InhibitorsProtein Geranylgeranyltransferase Type IBiochemistry of Rab GeranylgeranyltransferasePostisoprenylation Protein Processing: CXXX (CaaX) Endoproteases and Isoprenylcysteine Carboxyl MethyltransferaseReversible Modification of Proteins with Thioester-Linked Fatty AcidsBiology and Enzymology of Protein N-Myristoylation