Molecular Biology of RGS Proteins

Dr. Fisher is a 1983 graduate of Iowa State University (Ph.D.), who performed post-doctoral research at the University of Texas Health Science Center, San Antonio, before joining the faculty in Pharmacology at the University of Iowa in 1987. He was promoted to associate professor in 1993 and to professor in 2004. He has a secondary appointment in the Department of Internal Medicine and is a member of the Molecular and Cellular Biology interdisciplinary graduate program, the Holden Cancer Center, the Medical Scientist Training Program, and the Gene Therapy Center. His research focuses on the biology and signaling of RGS proteins and G proteins. He has served on numerous NIH study sections and his funding includes an R01 to study novel actions of RGS6 in tumor suppression and DNA damage signaling.

• 1. RGS proteins: the early daysHenrik Dohlman2. The role of RGS proteins in addiction, depression and Parkinsons diseaseVanna Zachariou3. Biology and functional regulation of RGS9 isoformsKirill Martemyanov4. RGS protein function in C. elegansMichael Koelle 5.G Beta 5 in the visual systemJason Chen 6. Roles of RGS proteins and RGS homology domains in signalingJohn Tesmer7.Gb5-RGS protein complexesVladlen Slepak8. Multifunctional roles of RGS Proteins in cellular signalingJohn Hepler 9. RGS protein control of lymphocyte functionJohn Kehrl10. RGS-insensitive G proteins to study endogenous RGS protein functionRichard Neubig 11. Alternative splicing of RGS transcripts and nuclear RGS proteinsRory Fisher