Ghrelin

Inbunden, Engelska, 2012

2 184 kr

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Beskrivning

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers ghrelin, and has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice.

Contains quality chapters authored by leaders in the field
Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice

Produktinformation

Utgivningsdatum:2012-11-09
Mått:152 x 229 x undefined mm
Vikt:840 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Enzymology
Antal sidor:512
Förlag:Elsevier Science
ISBN:9780123812728

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Innehållsförteckning

1. History of GHS and ghrelin2. History To The Discovery Of Ghrelin3. Orphan Gpcrs And Methods For Identifying Their Ligands4. Purification Of Rat And Human Ghrelins5. Variety of Acyl Modifications in Mammalian Ghrelins6. Determination Of Non-Mammalian GhrelinMolecular forms of ghrelin and Measuring of the concentrations7. Morphological Analysis Of Ghrelin Neurons In The Hypothalamus8. High-Performance Liquid Chromatography Analysis Of Hypothalamic Ghrelin9. Standard Sample Collections For Blood Ghrelin MeasurementsEnzymes for processing of ghrelin10. From Ghrelin to Ghrelin’s O Acyl Transferase11. Enzymatic Characterization Of Goat, Ghrelin O-Acyltransferase12. The Study Of Ghrelin Deacylation EnzymesSynthesis of ghrelin agonists and antagonists13. Synthesis Of Ghrelin Chemical Synthesis And Semi-Synthesis For Large-Scale Preparation Of Modified Peptides14. Ghrelin O-Acyltransferase Assays And InhibitionAction of ghrelin15. Model-Based Evaluation Of Growth Hormone Secretion16. Ghrelin In The Control Of Energy, Lipid And Glucose Metabolism17. Ghrelin And The Vagus Nerve18. Measurement of amp-activated protein kinase (ampk) activity and expression In response to ghrelin19. Ghrelin And Gastrointestinal Movement20. Ghrelin Acylation By Ingestion Of Medium-Chain Fatty Acids21. Islet ß-cell Ghrelin Signaling For Inhibition Of Insulin Secretion22. Rikkunshito As A Ghrelin EnhancerTg and KO mice of ghrelin23. Thermogenic Characterization Of Ghrelin Receptor Null Mice24. Transgenic Mice Over-Expressing Ghrelin Or Ghrelin AnalogClinical application of ghrelin25. Therapeutic Potential Of Ghrelin In Restricting-Type Anorexia Nervosa26. Clinical Application Of Ghrelin For Chronic Respiratory Diseases 27. Clinical Trial Of Ghrelin Synthesis Administration For Upper Gi Surgery