Glycosaminoglycans in Development, Health and Disease

Lijuan Zhang is a Professor of Translational Medicine at Ocean University of China. She completed her doctorates of biochemistry and molecular genetics at University of Alabama at Birmingham in 1995. Before then, she was a Fogarty International Fellow at NIH for three years studying glycan-based cancer biomarkers. She worked as post-doctorate fellow and research associate at both MIT and Harvard Medical School from 1995-2002. She joined the faculty of the Department of Pathology & Immunology at Washington University in St. Louis in 2002 as a tenure-tracked Assistant Professor. Her research had been focused on the biosynthesis, structures, and biological functions of glycans since 1985. Now her work is on translational aspects of glycans as biomarkers and therapeutics. She has over 60 peer reviewed publications. She edited and published a book entitled “Glycosaminoglycans in Development, Health, and Diseases” with the contributions of top scientists worldwide in 2010 by Elsevier.

PRAISE FOR THE SERIES: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

• Mice deficient in heparan sulfate N-sulphotransferase-1Lena Kjellén and Maria RingvallMice deficient in heparan sulfate epimeraseJin ping LiMice deficient in heparan sulfate 3-O-sulfotransferase-1Nicholas W. ShworakMice deficient in heparan sulfate 6-O-sulfotransferase-1Koji Kimata and Hiroko HabuchiMice deficient in dermatan sulfate EpimeraseMarco Maccarana and Anders MalmströmThe roles of chondroitin-4-sulfotransferase-1 in development and diseaseMichael KlüppelConditionally disrupted EXT1 in the embryonic mouse brain.Yu YamaguchiEndothelial heparan sulfate in inflammationJeffrey D. Esko and Ding XuEndothelial heparan sulfate in angiogenesisJeffrey D. Esko, Mark M. Fuster and Lianchun WangHepatocyte heparan sulfate and lipoprotein metabolismJeffrey D. Esko and Erin FoleySerglycin proteoglycan deletion in mouse plateletBarbara P. SchickGAGs in AmyloidosisJin ping Li and Xiao ZhangSelectins, Heparins and Tumor MetastasisLubor BorsigChondroitin sulfate and Rheumatoid arthritisLijuan ZhangAdducted thumb-clubfoot syndrome (ACTS) and Loss of dermatan-4-sulfotransferase 1 functionJacques U Baenziger,Thomas Müller, Andreas Janecke and Lijuan ZhangVascular dermatan sulfate and heparin cofactor IIDouglas M. TollefsenDiverse Functions of Glycosaminoglycans in Infectious DiseasesPyong Woo Park, Rafael Aquino, and Eui Seung LeeLessons learned from contaminated heparin. 1: Molecular mechanism underlines heparin induced thrombocytopenia and thrombosis.Lijuan ZhangLessons learne from contaminated heparin. 2: Contact System Activation-induced Thrombin in Unrelated Human Thromboembolic Diseases Lijuan Zhang, Peter Weiser, Yi Qian and Jing Pan