Basic Science Methods for Clinical Researchers

AvMorteza Jalali,Francesca Yvonne Louise Saldanha

Häftad, Engelska, 2017

944 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data.

This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science.

Serves as a helpful guide for clinical researchers who lack a conventional science background
Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms
Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data
Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Produktinformation

Utgivningsdatum:2017-04-04
Mått:150 x 226 x 23 mm
Vikt:613 g
Format:Häftad
Språk:Engelska
Antal sidor:382
Förlag:Elsevier Science
ISBN:9780128030776

Utforska kategorier

Mer om författaren

Morteza Jalali is a British doctor-preneur who is fascinated by transformational healthcare innovation through synergies between clinicians, patients, industry and scientists. Born in Manchester, United Kingdom, at the age of 18 he commenced a medical degree at Manchester Medical School and undertook dedicated research training at The Healing Foundation Centre, University of Manchester, following the award of a Royal College of Surgeons student research scholarship. After the completion of his Bachelor’s, Master’s and medical degrees, Morteza decided to undertake a Doctor of Philosophy degree in stem cell biology at the Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and was awarded a Cambridge Cancer Centre clinical research training fellowship to study at Emmanuel College, University of Cambridge. Morteza is committing to a career as a surgeon scientist by undertaking a period of postdoctoral research in the United States. He is currently a surgeon in training (plastic surgery theme) and honorary research fellow at the University of Oxford where he enjoys fulfilling a variety of clinical teaching commitments, having been a former faculty member at the University of Bristol. Morteza enjoys rowing, amateur boxing, graphic design, and spending time with family and friends in the United Kingdom and abroad. Clinical Research Fellow (M.Phil.), Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA, USA Academic Foundation Doctor, Royal Liverpool University Hospital, Liverpool, UK

Recensioner i media

"The information provided would be an excellent tool for a clinician in training…the content is best suited for those clinicians who lack basic science training or a research background."--Annals of Allergy, Asthma & Immunology

Innehållsförteckning

1. The Polymerase Chain Reaction: PCR, qPCR, and RT-PCR2. Methods of Cloning3. Whole-Mount In Situ Hybridization and a Genotyping Method on Single Xenopus Embryos4. Microarrays: An Introduction and Guide to Their Use5. Analysis of Human Genetic Variations Using DNA Sequencing6. Western Blot7. The Enzyme-Linked Immunosorbent Assay: The Application of ELISA in Clinical Research8. Immunofluorescence9. Cell Culture: Growing Cells as Model Systems In Vitro10. Flow Cytometry11. Transfection12. In Vivo Animal Modeling: Drosophila13. Zebrafish as a Research Organism: Danio rerio in Biomedical Research14. Xenopus as a Model Organism for Biomedical Research15. Basic Mouse Methods for Clinician Researchers: Harnessing the Mouse for Biomedical Research