Encyclopedia of Spectroscopy and Spectrometry

Dr. John C. Lindon is a professor and senior research investigator in the Division of Computational and Systems Medicine, part of the Department of Surgery and Cancer, Imperial College London. He is also a founder, director of, and a consultant to Metabometrix Ltd, a company spun out of Imperial College to exploit the commercial possibilities of metabolic phenotyping. He is editor in chief of the Encyclopedia of Spectroscopy and Spectrometry and is on the editorial board of several journals. His major research interest is the use of NMR and other analytic methods coupled with multivariate statistics to study biofluids and tissues, a field now termed metabolic phenotyping. George E. Tranter PhD MA BSc FRSC CChem CSci, has held senior R&D positions in both industry and academia (including at London University, Oxford University, the Wellcome Foundation and GlaxoWellcome). Until 2006 he led the Biospectroscopy Centre of Imperial College London and subsequently was Senior Research Fellow of the Department of Chemistry, University of Oxford. He is a recognized international authority in the field of molecular chirality and the spectroscopic/physicochemical features of drugs and biopharmaceuticals. He is named as inventor on drug patents, has published widely in the scientific literature, co-edited The Encyclopedia of Spectroscopy & Spectrometry (Academic Press), editor of the Separations and Analysis volume of Comprehensive Chirality (Elsevier), has been a member of scientific journal editorial boards (inc. CHIRALITY) and appeared on radio and television programmes in the UK and abroad. He is also a member of various scientific advisory panels and is a key partner in collaborations that bring together the biopharmaceutical industry, academia, and governmental institutions to investigate and validate biopharmaceutical structure and function. His particular interests are in the rational discovery of new therapeutics, with a passion for the role chirality plays in nature, from the molecular level through to macroscopic structures (e.g., helical shells) and beyond.istics of marine creatures. David W. Koppenaal is Chief Technology Officer at the Enviromental Molecular Sciences Center (EMSL) at Pacific Northwest National Laboratory in Richland, WA. Dr. Koppenaal’s research interests include the development of new instrumental and spectroscopic techniques for metallomics applications and the metallomic study of cyanobacterial systems. Dr. Koppenaal was an early proponent of metallomics as a new science discipline, serving as an advocate and speaker on this topic since 2000, organizing the first symposia focused on this topic in the US, and serving as co-chair of the 2nd International Metallomics Symposium (2009). Dr. Koppenaal is well-known for his fundamental science investigations and innovations in atomic mass spectrometry, including the initial development and demonstration of effective reaction cell technology and associated ion molecule reaction approaches for interference reduction in ICPMS. More recently he has developed and applied ultra-high resolution orbital trapping MS techniques to metallomics applications. Dr. Koppenaal has also served as Editorial Board member of JAAS, and as Chair of the Analytical Division of the American Chemical Society. He is a Fellow of the Royal Society of Chemistry, the American Association for the Advancement of Science, and the American Chemical Society.

Reviews of the first edition:"There are many professionals . . . who would profit from this set in their libraries." --Choice"Outstanding effort . . . the entries [are] authoritative, with many written by the best-known workers in the field. A good balance of both breadth and depth of coverage." --Applied Spectroscopy "This opus of more than 3,300 pages covers an extraordinary range of topics relating to spectroscopy and mass spectrometry. Editors Lindon, Tranter, and Koppenaal are specialists in biological NMR spectroscopy, chiral analytical methods, and atomic mass spectrometry, respectively. This edition represents a major update; though the majority of entries are reprinted verbatim from the first edition (CH, Dec'00, 38-2171; edited by Lindon, Tranter, and J. L. Holmes), the second edition features many new entries focused mainly on technologies that emerged in the last decade. These include proteomics and NMR studies on biofluids. Entries in the encyclopedia are classified as theory, methods/instrumentation, applications, historical perspectives, or overviews and are written in the style of a review journal article, ranging from about 5 to 15 pages. Clearly written and containing numerous figures (some in full color), tables, and extensive references, entries are mostly understandable to a typical working chemist, though a minority are quite specialized. The alphabetical arrangement is usable, but a subject-based arrangement might be more convenient for researching related topics.This encyclopedia is unique in its scope and depth. It aims to assemble a comprehensive, balanced collection of information about both established and cutting-edge spectroscopic and spectrometric science, covering theoretical and practical aspects while maintaining readability and accessibility. Inevitably, in such an ambitious work, some important topics in rapidly evolving fields will be overlooked; e.g., little mention is made of the electron-transfer dissociation technique in mass spectrometry. Entries reprinted from the first edition were not updated at all. While newer entries often bring the information up-to-date, some of the older entries remain outdated, particularly in their bibliographies. Overall, this encyclopedia gathers vast amounts of information into a single work. Though imperfect, it is useful for working chemists and for others, including advanced students, as a reference in spectroscopy and spectrometry from ATR to Zeeman.Summing Up: Recommended. Upper-division undergraduates through professionals/practitioners." --E. J. Chang, York College, Choice, 2011

• Induced Circular DichroismSurface Plasmon Resonance, ApplicationsSymmetry in Spectroscopy, Effects ofTensor RepresentationsCalibration and Reference Systems (Regulatory Authorities)Photoelectron SpectroscopyX-Ray Spectroscopy, TheoryZero Kinetic Energy Photoelectron Spectroscopy, TheoryX-Ray Fluorescence Spectroscopy, ApplicationsZero Kinetic Energy Photoelectron Spectroscopy, ApplicationsMagnetic Resonance, Historical PerspectiveContrast Mechanisms in MRIApplications of Single Photon ImagingVibrational, Rotational and Raman Spectroscopy, Historical PerspectiveIR Spectroscopy, TheoryNonlinear Raman Spectroscopy, TheoryVibrational CD, TheoryHigh Resolution Gas Phase IR Spectroscopy InstrumentationNonlinear Raman Spectroscopy, InstrumentsRaman SpectrometersMedical Science Applications of IRSurface Studies by IR SpectroscopyChiroptical Spectroscopy, General TheoryScattering TheoryChiroptical Spectroscopy, Oriented Molecules and Anisotropic SystemsPhotoelectron SpectrometersX-Ray Absorption SpectrometersX-Ray Fluorescence SpectrometersChemical Exchange Effects in NMRNMR Pulse Sequences13C NMR, MethodsNMR Data ProcessingEnantiomeric Purity Studied Using NMRHeteronuclear NMR Applications (Sc