Neuroblastoma

Dr. Ray is senior faculty at the University of South Carolina School of Medicine with a deep interest in neuro-oncology. He has been working in the neuroblastoma field for more than 10 years has over 175 publications in the field and is funded by the federal, state, and private funding agencies for conducting his research. His laboratory focuses on the understanding of the cellular and molecular mechanisms of pathogenesis of malignant diseases such as glioblastoma, neuroblastoma, and Ewing's sarcoma and the development of novel therapeutic strategies for neurological disorders. He has trained many students, postdoctoral fellows, and junior faculty members as well.

• 1. Neuroblastoma pathology and classification2. Role of genetic and epigenetic alterations in pathogenesis of neuroblastoma3. Neuroblastoma molecular biology and promising therapeutic targets4. The GD2-targeted immunotherapy of neuroblastoma5. Targeting angiogenesis in neuroblastoma6. Autophagy and novel therapeutic strategies in neuroblastoma7. Energy metabolism and new therapeutic opportunities in neuroblastoma8. Multimodality imaging for diagnosis of neuroblastoma9. Immunotherapy for neuroblastoma10. Advances in surgical treatment of neuroblastoma11. Role of stemness factors in neuroblastoma: Neuroblastoma stem cells, tumor microenvironment, and chemoresistance12. Current pharmacotherapy for neuroblastoma13. Current challenges in the management of neuroblastoma14. Novel therapeutic targets in neuroblastoma15. Current and future strategies for treatment of relapsed neuroblastoma16. Current evidence in favor of a tumor suppressor role of Krüppel-like factor 4 in malignant neuroblastoma17. Modulation of expression of microRNA as a therapeutic strategy in malignant neuroblastoma