Microbiology of Metal Ions

Professor Robert K Poole is Emeritus Professor of Microbiology at the University of Sheffield, UK. He was previously West Riding Professor of Microbiology at Sheffield and until 1996 held a Personal Chair in Microbiology at King’s College London. During his long career, he has been awarded several research Fellowships, and taken sabbatical leave at the Australian National University, Kyoto University and Cornell University. His career-long interests have been in the areas of bacterial respiratory metabolism, metal-microbe interactions and bioactive small gas molecules. In particular, he has made notable contributions to bacterial terminal oxidases and resistance to nitric oxide with implications for bacterial pathogenesis. He co-discovered the flavohaemoglobin Hmp, now recognised as the preeminent mechanism of nitric oxide resistance in bacteria. He has served as Chairman of numerous research council grant committees, held research grants for over 40 years and published extensively (h-index, 2024 = 70). He served on several Institute review panels in the UK and overseas. He is a Fellow of the Royal Society of Chemistry and the Royal Society of Biology.

• 1. Bacterial Haemoprotein Sensors of NO: H-NOX and NosP2. Manganese in Marine Microbiology3. Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface4. Metal-Based Combinations that Target Protein Synthesis by Fungi5. Transition Metal Homeostasis in Streptococcus Pyogenes and Streptococcus Pneumoniae6. Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal Applications7. Metal Resistance and Its Association with Antibiotic Resistance8. The Role of Intermetal Competition and Mis-Metalation in Metal Toxicity