Stress: Genetics, Epigenetics and Genomics

Dr. Fink is Honorary Professor in the University of Melbourne and Professorial Research Fellow at the Florey Institute of Neuroscience and Mental Health. Formerly, he was Scientific Director of the Mental Health Research Institute, Melbourne, Australia. Before returning to Melbourne in 2003, Dr. Fink was University Lecturer in Human Anatomy and Fellow in Physiology and Medicine at Brasenose College and the University of Oxford and served for nearly 20 years as CEO and Director of the UK Medical Research Council’s Brain Metabolism Unit in Edinburgh. He gained distinction through his seminal research discoveries in neuroendocrinology and psychopharmacology published in over 360 scientific papers. Dr. Fink served as President of the European Neuroendocrine Association. His distinctions include Fellow of the Royal Society of Edinburgh, Fellow of the Royal College of Physicians of Edinburgh, Fellow of the Royal Biological Society, Fellow of the Physiological Society, and Honorary Member of the British Society for Neuroendocrinology. Fink was Honorary Professor in the University of Edinburgh, delivered the inaugural Geoffrey Harris Prize Lecture of the British Physiological Society, and the Wolfson Lecture. In 1979 he was awarded the Royal Society - Israel Academy Exchange Fellowship which enabled him to spend a research year at the Weizmann Institute of Science, Rehovot Israel. In 2000 he was awarded the Lifetime Achievement Award of the International Society of Psychoneuroendocrinology. His membership of learned societies includes Emeritus member of the Society for Neuroscience, the Endocrine Society and the Genetics Society of America. Dr. Fink has edited several scientific books with Elsevier, including Stress Science: Neuroendocrinology (2009), Stress Consequences: Mental, Neuropsychological and Socioeconomic (2009), Stress of War, Conflict and Disaster (2010), the Handbook of Neuroendocrinology (2011), and most notably the 4-volume second edition of the Encyclopedia of Stress (2007) on which this new Handbook of Stress series is based. He was founding Editor-in-Chief of the first edition of the Encyclopedia of Stress (2000) which was awarded the 2001 British Medical Association commendation for its contribution to Mental Health. The first volume of his Handbook of Stress series, entitled “Stress: Concepts, Cognition, Emotion, and Behavior”, received the BMA High Commendation in the Health and Social Care category as one of the top titles in its discipline.

• 1. Genetic Dissection of Neuropeptide Circuits Mediating Psychosocial StressYAIR J. BEN-EFRAIM AND ALON CHEN2. Genetic Variation of HPA Axis Activity and Function in Farm AnimalsPIERRE MORMEDE AND ELENA TERENINA3. MicroRNAs and the Response to StressSHARON L. HOLLINS AND MURRAY J. CAIRNS4. Stress-Mediated Regulation of the DNA MethylomeALEC LINDSAY WARD DICK AND ALON CHEN5. Genomics and Epigenetics of Plant Abiotic StressSUPRASANNA PENNA, POOJA NEGI, AND VINAY KUMAR6. The Long-Term Biological and Clinical Consequences of Child Abuse and NeglectJONATHAN PARKER AND CHARLES B. NEMEROFF7. Transcriptional and Epigenetic Regulation of the Corticotropin-Releasing Hormone System and Genetic Associations With Neuropsychiatric DisordersJAN M. DEUSSING8. Circadian Clocks, Stress, and Psychiatric DisordersCHARLOTTE KLING AND DOMINIC LANDGRAF9. Effects of Psychological Stress on Telomeres as Genome RegulatorsLAURA C. ETZEL AND IDAN SHALEV10. From Exaptation to Adaptation: Stress, Transposons, and Functions of the Deep GenomeANDREW A. BARTLETT AND RICHARD G. HUNTER11. Fetal Alcohol Exposure Impairs the Function of Hypothalamic Proopiomelanocortin Neurons via a Circadian MechanismDIPAK K. SARKAR12. Molecular Signaling in the Gut–Brain Axis in StressAMANDA J. PAGE AND HUI LI13. Stress Responsiveness of BDNF/TrkB Signaling in the Neuroendocrine System and Future ImplicationsI. AZOGU-SEPE AND H. PLAMONDON14. Estradiol Protects Hypothalamic Neurons Against Insulin ResistanceOLINE K. RØNNEKLEIV AND MARTIN J. KELLY15. Genetics of Stress ResponsivenessYVETTE M. WILSON, JENNY M. GUNNERSEN, AND MARK MURPHY16. miRNAs of Astrocyte-Derived Small Extracellular Vesicles Potentially Modulate Adult Neurogenesis Under Stress ConditionsFELIPE BUSTAMANTE, MAXS M_ENDEZ-RUETTE, URSULA WYNEKEN, LUIS FEDERICO BA´ TIZ, AND ROBERTO HENZI17. Gonadotropin-Releasing Hormone (GnRH) and Corticotropin-Releasing Factor (CRF): An Evolutionary History of InteractionDAVID A. LOVEJOY AND DAVID W. HOGG18. New Vistas of Old Terrains: Magnocellular Vasopressin and the Neuroendocrine Response to StressFERENC A. ANTONI19. Responding to Stress: Genomic and Nongenomic Actions of Corticosteroid Receptors in the BrainSAMANTHA N. HAQUE, KAREN R. MIFSUD, EMILY M. PRICE, AND JOHANNES M.H.M. REUL20. Mutations of the Human Mineralocorticoid Receptor and Targeted Deletion in Model OrganismsTIMOTHY J. COLE, PETER J. FULLER, AND MORAG J. YOUNG21. Mechanisms Regulating Hypoxia Tolerance in Drosophila and HumansDAN ZHOU, PRITI AZAD, TSERING STOBDAN, AND GABRIEL G. HADDAD22. Brain-Derived Neurotrophic Factor and Its Role in Stress-Related DisordersMICHAEL NOTARAS AND MAARTEN VAN DEN BUUSE23. Zebrafish Models for Stress ResearchMURILO S. DE ABREU, KONSTANTIN A. DEMIN, TAMARA G. AMSTISLAVSKAYA, TATYANA STREKALOVA, AND ALLAN V. KALUEFF24. Epigenetic Effects of Exercise on Human Skeletal MuscleMACSUE JACQUES, SHANIE LANDEN, ANDREW S. PALMER, AND NIR EYNON25. Exercise and/or Stress Effects on the Epigenetic ClockSARAH VOISIN26. Telomeres and Early-Life StressSTEFANIE MAYER, QUINN CONKLIN, SAMUEL J. RIDOUT, AND KATHRYN K. RIDOUT27. Molecular Responses to Heat Stress in Escherichia coliXU-TING WANG, SHI-DI XIAO, AND BIN-GUANG MA28. Epigenetics and the Impact of Early-Life Stress Across GenerationsGRETCHEN VAN STEENWYK AND ISABELLE M. MANSUY29. Corticolimbic Circuitry and Genomic Risk for Stress-Related PsychopathologySARAH E. PAUL, NOURHAN M. ELSAYED, ERIN BONDY, AND RYAN BOGDAN