Udi Nussinovitch, MD, PhD graduated from the Sackler Faculty of Medicine, Tel Aviv University, training at the Sheba Medical Center, Rambam Healthcare Center and Meir Medical Center, while concurrently graduating with a PhD in cardiac electrophysiology from the Technion Institute of Technology, Israel.Dr Nussinovitch has dedicated his research to investigating novel therapeutic approaches for cardiac disorders and the modulation of the cardiac electrophysiologic substrate for therapeutic purposes. He serves as director of the Applicative Cardiovascular Research Center (ACRC), affiliated to Tel Aviv University. Dr Nussinovitch founded several biotech companies, and has been the recipient of several research awards. He carries out his clinical work at the Meir Medical Center, a medical facility and leading referral center in Israel.

"This book will be a valuable resource for healthcare providers and innovators in the field of cardiovascular medicine. It provides a comprehensive overview of the current and novel treatment options for heart failure and valvular disease." --Doody

• SECTION 1: Treatment of heart failure – device-based therapies and monitoring modalities1. Keeping a Finger on the Pulse - A brief history of cardiovascular medicine2. Artificial mechanical hearts and ventricular assist devices3. Percutaneous left and right ventricular support devices4. Cardiac resynchronization therapy5. Left atrial decompression devices6. Device-based treatment for diastolic heart failure7. Ultrafiltration and other treatments of volume overload in congestive heart failure8. Cardiac physical remodeling and percutaneous solutions for the treatment of advanced Heart FailureSECTION 2: Treatment of systolic heart failure - cell and gene-based therapies, tissue engineering and biopolymers9. Cardiac xenotransplantation10. Marrow-derived stromal cells for cardiac regeneration11. Heart-derived cells for therapeutic application12. Human Pluripotent Stem Cells for Cardiac Regeneration13. Heart Regeneration Using Somatic Cells14. In-vitro engineered heart tissue grafts15. Decellularization of whole hearts for cardiac regeneration16. Gene and protein-based therapies for improving cardiac performance and regeneration17. Biopolymers in the treatment of heart failure and cardiac remodelingSECTION 3: Treatment of systolic heart failure - novel pharmacological treatments18. Novel pharmacotherapies for the treatment of heart failureSECTION 4: Treatment of valvular disorders 19. Heart Valve Tissue Engineering: Current Preclinical and Clinical approaches20. Transcatheter aortic valve replacement21. Transcatheter mitral valve repairs for degenerative and Functional mitral regurgitation22. Transcatheter mitral valve implantation23. Transcatheter treatments for tricuspid valve diseases

Udi Nussinovitch, MD, PhD graduated from the Sackler Faculty of Medicine, Tel Aviv University, training at the Sheba Medical Center, Rambam Healthcare Center and Meir Medical Center, while concurrently graduating with a PhD in cardiac electrophysiology from the Technion Institute of Technology, Israel.Dr Nussinovitch has dedicated his research to investigating novel therapeutic approaches for cardiac disorders and the modulation of the cardiac electrophysiologic substrate for therapeutic purposes. He serves as director of the Applicative Cardiovascular Research Center (ACRC), affiliated to Tel Aviv University. Dr Nussinovitch founded several biotech companies, and has been the recipient of several research awards. He carries out his clinical work at the Meir Medical Center, a medical facility and leading referral center in Israel.

"This book will be a valuable resource for healthcare providers and innovators in the field of cardiovascular medicine. It provides a comprehensive overview of the current and novel treatment options for heart failure and valvular disease." --Doody

• SECTION 1: Treatment of heart failure – device-based therapies and monitoring modalities1. Keeping a Finger on the Pulse - A brief history of cardiovascular medicine2. Artificial mechanical hearts and ventricular assist devices3. Percutaneous left and right ventricular support devices4. Cardiac resynchronization therapy5. Left atrial decompression devices6. Device-based treatment for diastolic heart failure7. Ultrafiltration and other treatments of volume overload in congestive heart failure8. Cardiac physical remodeling and percutaneous solutions for the treatment of advanced Heart FailureSECTION 2: Treatment of systolic heart failure - cell and gene-based therapies, tissue engineering and biopolymers9. Cardiac xenotransplantation10. Marrow-derived stromal cells for cardiac regeneration11. Heart-derived cells for therapeutic application12. Human Pluripotent Stem Cells for Cardiac Regeneration13. Heart Regeneration Using Somatic Cells14. In-vitro engineered heart tissue grafts15. Decellularization of whole hearts for cardiac regeneration16. Gene and protein-based therapies for improving cardiac performance and regeneration17. Biopolymers in the treatment of heart failure and cardiac remodelingSECTION 3: Treatment of systolic heart failure - novel pharmacological treatments18. Novel pharmacotherapies for the treatment of heart failureSECTION 4: Treatment of valvular disorders 19. Heart Valve Tissue Engineering: Current Preclinical and Clinical approaches20. Transcatheter aortic valve replacement21. Transcatheter mitral valve repairs for degenerative and Functional mitral regurgitation22. Transcatheter mitral valve implantation23. Transcatheter treatments for tricuspid valve diseases

Udi Nussinovitch, MD, PhD graduated from the Sackler Faculty of Medicine, Tel Aviv University, training at the Sheba Medical Center, Rambam Healthcare Center and Meir Medical Center, while concurrently graduating with a PhD in cardiac electrophysiology from the Technion Institute of Technology, Israel.Dr Nussinovitch has dedicated his research to investigating novel therapeutic approaches for cardiac disorders and the modulation of the cardiac electrophysiologic substrate for therapeutic purposes. He serves as director of the Applicative Cardiovascular Research Center (ACRC), affiliated to Tel Aviv University. Dr Nussinovitch founded several biotech companies, and has been the recipient of several research awards. He carries out his clinical work at the Meir Medical Center, a medical facility and leading referral center in Israel.

"This book will be a valuable resource for healthcare providers and innovators in the field of cardiovascular medicine. It provides a comprehensive overview of the current and novel treatment options for heart failure and valvular disease." --Doody

• SECTION 1: Treatment of heart failure – device-based therapies and monitoring modalities1. Keeping a Finger on the Pulse - A brief history of cardiovascular medicine2. Artificial mechanical hearts and ventricular assist devices3. Percutaneous left and right ventricular support devices4. Cardiac resynchronization therapy5. Left atrial decompression devices6. Device-based treatment for diastolic heart failure7. Ultrafiltration and other treatments of volume overload in congestive heart failure8. Cardiac physical remodeling and percutaneous solutions for the treatment of advanced Heart FailureSECTION 2: Treatment of systolic heart failure - cell and gene-based therapies, tissue engineering and biopolymers9. Cardiac xenotransplantation10. Marrow-derived stromal cells for cardiac regeneration11. Heart-derived cells for therapeutic application12. Human Pluripotent Stem Cells for Cardiac Regeneration13. Heart Regeneration Using Somatic Cells14. In-vitro engineered heart tissue grafts15. Decellularization of whole hearts for cardiac regeneration16. Gene and protein-based therapies for improving cardiac performance and regeneration17. Biopolymers in the treatment of heart failure and cardiac remodelingSECTION 3: Treatment of systolic heart failure - novel pharmacological treatments18. Novel pharmacotherapies for the treatment of heart failureSECTION 4: Treatment of valvular disorders 19. Heart Valve Tissue Engineering: Current Preclinical and Clinical approaches20. Transcatheter aortic valve replacement21. Transcatheter mitral valve repairs for degenerative and Functional mitral regurgitation22. Transcatheter mitral valve implantation23. Transcatheter treatments for tricuspid valve diseases