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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Biologi
    4. Biovetenskap

    Prognostic Epigenetics

    Inbunden, Engelska, 2019

    Del 15 i serien Translational Epigenetics

    1 938 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    This volume provides comprehensive information on how mapping an individual's epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases.

    Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.



    • Compiles all known information on prognostic epigenetics and its role in preventive medicine and drug discovery
    • Covers the basic functionality of epigenetic mechanisms involved in early disease prognosis and diagnosis, and provides tools for the identification and development of these biomarkers for a wide range of diseases
    • Enables clinicians, researchers, and pharmacologists to improve preventive medicine and precision therapeutics throughout a person's lifetime
    • Features chapter contributions from leading international researchers

    Produktinformation

    • Utgivningsdatum:2019-11-04
    • Mått:191 x 235 x undefined mm
    • Vikt:1 020 g
    • Format:Inbunden
    • Språk:Engelska
    • Serie:Translational Epigenetics
    • Antal sidor:442
    • Förlag:Elsevier Science
    • Medarbetare:Shilpy Sharma
    • ISBN:9780128142592

    Utforska kategorier

    • Biovetenskap inom Naturvetenskap och teknik

    Mer om författaren

    Dr. Shilpy Sharma, PhD, is an Assistant Professor at the Department of Biotechnology, Savitribai Phule Pune University (Formerly University of Pune) in Pune, Maharashtra, India. She has served as a Post-Doctoral Fellow in the Department of Pharmacology at University of Michigan and as a Post-Doctoral Fellow at the Department of Surgery, University of Chicago Medical Center. Dr. Sharma’s research focuses on identification of prognostic biomarkers for complex disorders including cancer, diabetes, and asthma; and infectious diseases.

    Recensioner i media

    "Several books in epigenetics exist in the literature, however, a good number of them provide only basic concepts. The value of this book is its provocative idea of utilizing epigenetic factors to reduce, modify, and/or treat human conditions. It provides a perfect link between the area of epigenetics and precision medicine." --Doody

    Innehållsförteckning

    • 1. It is more than simple genes: The epigenome is more powerful than your genome2. Diagnostic, prognostic and therapeutic potential of the inter-individual variability in the major epigenetic processes: A Clinical Prospective3. Technological advances in studying epigenetics biomarkers for clinical research4. DNA methylation and Chromatin remodeling: Potential prognostic biomarker for disease diagnosis5. Use of post-translational histone modifications for disease diagnosis6. Use of non-coding RNAs as Clinical Biomarkers for disease diagnosis7. The Epigenetic Landscape in Neurological and Neurodegenerative Disorders8. Epigenetic Biomarkers in Asthma and Allergy9. Epigenetics Biomarkers in Metabolic syndrome and Obesity10. Chromatin landscape and Epigenetic biomarkers for clinical diagnosis and prognosis of Type 2 Diabetes mellitus11. Epigenetic biomarkers in Cardiovascular disorders12. Epigenetic biomarkers in Cancer13. Epigenetics in Infectious diseases14. Epigenetics of autoimmune disorders15. Epigenetics of Birth defects16. Epigenetics of adverse pregnancy outcomes17. Epigenetic landscape of Infertility18.  Epigenetic landscape of polycystic ovarian syndrome19. Epigenetic biomarkers in ocular disorders20. Epigenetic biomarkers in personalized medicine21. Conclusions and Perspectives. Future Challenges and Prospects for Prognostic Epigenetics and personalized epigenomics