Biopharmaceutics and Pharmacokinetics Considerations

Inbunden, Engelska, 2021

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Beskrivning

Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce.

Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences
Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics
Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Produktinformation

Utgivningsdatum:2021-07-08
Mått:191 x 235 x 42 mm
Vikt:1 770 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Pharmaceutical Product Development and Research
Antal sidor:752
Förlag:Elsevier Science
Medarbetare:RakeshK. Tekade
ISBN:9780128144251

Utforska kategorier

Farmakologi inom Medicin
Medicin: icke kliniska discipliner inom Medicin
Biokemisk teknik inom Naturvetenskap och teknik

Mer om författaren

Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.

Innehållsförteckning

1. Routes of administrations and implication on drug bioavailability2. Biopharmaceutics and Pharmacokinetics considerations in drug research3. Bioavailability and bioequivalence research in Product Development4. Pharmacokinetic characterization of drugs and new product designing5. Pharmacokinetic Modulation with Particulate Drug Formulations6. Dose, Dosage regimen and Dose adjustment7. Implications of Bio-Nanotechnology in neuroscience, tissue engineering and cancer therapy8. Physiologic pharmacokinetics models: Application and limitations9. Chronopharmacokinetics in drug design10. Drug toxicity and forensic pharmacokinetics11. Recent advancements in Pharmacogenomics12. Biocompatibility testing of biomaterials and biologicals13. Metabolic kinetics14. Animal handling and ethical considerations15. Biopharmaceutic and pharmacokinetic aspects of controlled release systems16. Degradation of biomaterials in biological environment17. Safety and long-term toxicity evaluation of polymers used in Pharmaceutical Product Development: Regulatory considerations18. Toxicity and toxicokinetic consideration in product development and drug research19. Environmental and safety aspects of bio-nanotechnology20. Toxicity considerations on repetitive accumulation of polymeric materials