G Protein-Coupled Receptors, Part B

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

• 1. Optical approaches for visualization of arrestin binding to muscarinic receptorSeung Ryoung Jung2. Luciferase Reporter Assay for Unlocking Ligand-mediated Signaling of GPCRsHamiyet Unal3. Assays to measure GPCR dependent cellular migrationCarole A. Parent4. Characterization of the Frizzled GPCRsVladimir L. Katanaev5. Binding assays for bradykinin and angiotensin receptorsRenan Martin6. Detection of misfolded rhodopsin aggregates in cellsPaul Park7. Measuring GPCR ubiquitination and traffickingSamarjit Bhattacharyya8. Culture of primary neurons and its use in studying GPCR traffickingPrem N. Yadav9. ELISA based assay for measuring agonist-induced GPCR endocytosisArun K. Shukla10. Western blot assay for measuring agonist-induced ERK1/2 phosphorylationArun K. Shukla11. Understanding GPCR dimerizationAgata Faron-Górecka12. Investigating the Frizzled family of receptorsVladimir L. Katanaev13. Measuring GPCR signaling through xCELLigence system based assayLaura Heitman14. Novel mechanisms of GPCR signaling and biasGabriel Carmona Rosas15. co-IP assays to measure GPCR-arrestin interactionsAnastasios Lymperopoulos16. Investigating arrestin dependent GPCR signalingSadashiva Karnik17. Measuring CRH1 receptor signalingSusana Silberstein18. Site-specific side chain labeling for NMR studies of G protein-coupled receptorsBrian F. Volkman19. Modeling chemokine receptors and their orthosteric site interactionsBrian F. Volkman20. Receptor-channel cross-talkUri Kahanovitch21. Wnt receptor signalingNibaldo C. Inestrosa