Intracellular Signalling Proteins

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

• 1. Voices from the dead: The complex language and intricate grammar of dead cellsJerrold S. Levine and David S. Ucker2. Nucleobindins and encoded peptides: From cell signaling to physiologyAdelaine Leung, Naresh Ramesh, Christine Vogel and Suraj Unniappan3. Estrogen receptor signaling mechanismsNathalie Fuentes and Patricia Silveyra4. Intracellular signaling of the AMP-activated protein kinaseMiribane Dërmaku-Sopjani and Mentor Sopjani5. Relationship between mitofusin 2 and cancerAlessandro Allegra, Vanessa Innao, Andrea Gaetano Allegra and Caterina Musolino6. Molecular signaling in bone cells: Regulation of cell differentiation and survivalLilian I. Plotkin and Angela Bruzzaniti7. Activating mutations of the gp130/JAK/STAT pathway in human diseasesJuliane Lokau and Christoph Garbers8. Aquaporin water channels: New perspectives on the potential role in inflammationMargherita Sisto, Domenico Ribatti and Sabrina Lisi9. Intracellular protein complexes involved in synapse assembly in presynaptic neuronsKyung Ah Han, Ji Won Um and Jaewon Ko10. Dopamine signaling in the striatumEmmanuel Valjent, Anne Biever, Giuseppe Gangarossa and Emma Puighermanal11. Recent advances in computational studies of GPCR-G protein interactionsJinan Wang and Yinglong Miao12. From traveler to homebody: Which signaling mechanisms sponge larvae use to become adult sponges?Ilya Borisenko, Olga I. Podgornaya and Alexander V. Ereskovsky