Basic Fundamentals of Drug Delivery

Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.

• 1. Scientific rationale for designing controlled drug delivery systems2. Current developments in excipient science: Implication of quantitative selection of each excipient in product development3. Fundamentals of polymers science applied in Pharmaceutical Product Development4. Use of polymers in controlled release of active agents5. Co-polymers and block co-polymers in drug delivery and therapy6. Pharmaceutical and biomedical applications of polymers7. Levels of Drug targeting8. Ligands for targeted drug delivery and applications9. Transportation and bio interaction Properties in nanomaterials across biological systems10. Importance of preliminary characterisation of nanoparticles in pharmaceutical product development11. Biodegradable Block Copolymers and Their Applications For Drug Delivery12. Bio-Nanotechnology in pharmaceutical research13. Design and evaluation of ophthalmic delivery formulations14. Design and fabrication of Brain targeted drug delivery15. Cutaneous and transdermal drug delivery: Techniques and Delivery systems16. Protein/peptide drug delivery systems: Practical considerations in Pharmaceutical Product Development17. Nanocarriers in different preclinical and clinical stages18. Clinical aspects and regulatory requirements for nanomedicines