Dr. Hemanshu Prabhakar is a Professor at the Department of Neuroanaesthesiology and Critical Care at the All India Institute of Medical Sciences (AIIMS), New Delhi, India. He is a recipient of the AIIMS Excellence Award 2012 for his notable contribution to academia. He has a special interest in the evidence-based practice of neuroanesthesia and ERAS. Dr. Prabhakar is a Member of various national and international neuroanesthesia societies and is the Past Secretary of the Indian Society of Neuroanesthesia and Critical Care (ISNACC) and the Society of Neurocritical Care (SNCC). He is also the Immediate Past President of the SNCC. To date, he has published more than 25 books on neuroanesthesia and neurocritical care. He is featured in the Limca Book of Records as a prolific Writer in the field of neuroanesthesiology. He actively collaborates on research activities among the low-income and middle-income countries.

"This book is a great addition to the clinical decision making in neuroanesthesiology and neurocritical care, as evidence-based practice continues to reveal its importance in clinical scenarios. This book provides up-to-date evidence in a concise manner, with the help of comparison charts, algorithms, and consensus guidelines, which otherwise would require large amounts of time to cover in the vast literature. This book is unique as it is geared toward answering specific, hard clinical management questions with the most up-to-date evidence for the question or controversy at hand. In a few specific chapters, it is unable to give a strong consensus recommendation due to the lack of evidence currently available, but still presents sources of evidence for clinicians to individualize care for their patients. It does not provide textbook-type chapters that cover the whole management of a specific pathology, which makes it a great resource for advanced residents or practicing clinicians as it does require some basic knowledge to maximize its value. The book Problem Based Learning Discussions in Neuroanesthesia and Neurocritical Care, Prabhakar et al. (Springer, 2020), which shares multiple authors with this book including the editor, might be a more comprehensive and excellent addition to this book." --© Doody’s Review Service, 2021, Andres R Brenes Bastos, MD, reviewer, expert opinion"Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." --Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)

• Section A - Introduction1. Introduction to evidence-based practiceSection B - Neurophysiology2. ICP or CPP thresholds3. Role of hypothermia4. Mechanical ventilation—PEEPSection C - Neuropharmacology5. Intravenous or inhalational anesthetics?6. Hyperosmolar therapy7. Role of nitrous oxide8. Antimicrobial prophylaxis9. Role of antiepileptics10. Treatment of hypertension11. Role of statins for neuroprotection12. Role of stem cell therapy in neurosciencesSection D - Neuromonitoring13. ICP monitoring14. Type of ICP monitor15. Newer brain monitoring techniques16. Intraoperative neuromonitoringSection E - Neuromonitoring17. Blood transfusion triggers18. Reversal of anticoagulation in neurosurgical and neurocritical care settings19. Role of decompressive craniectomy20. Strategies for brain protection21. Anesthesia for carotid endarterectomy22. Anesthesia for acute stroke23. Anesthesia for spine surgerySection F - Neurointensive care24. Choice of sedation in ICU25. DVT prophylaxis26. Role of steroids27. Initiation of nutrition28. Glycemic control29. Anesthetics for status epilepticusSection G - Ethical issues30. Diagnosing brain deathSection H - Recent advances31. Simulations in clinical neurosciencesSection I - Webliography32. Webliography

Dr. Hemanshu Prabhakar is a Professor at the Department of Neuroanaesthesiology and Critical Care at the All India Institute of Medical Sciences (AIIMS), New Delhi, India. He is a recipient of the AIIMS Excellence Award 2012 for his notable contribution to academia. He has a special interest in the evidence-based practice of neuroanesthesia and ERAS. Dr. Prabhakar is a Member of various national and international neuroanesthesia societies and is the Past Secretary of the Indian Society of Neuroanesthesia and Critical Care (ISNACC) and the Society of Neurocritical Care (SNCC). He is also the Immediate Past President of the SNCC. To date, he has published more than 25 books on neuroanesthesia and neurocritical care. He is featured in the Limca Book of Records as a prolific Writer in the field of neuroanesthesiology. He actively collaborates on research activities among the low-income and middle-income countries.

"This book is a great addition to the clinical decision making in neuroanesthesiology and neurocritical care, as evidence-based practice continues to reveal its importance in clinical scenarios. This book provides up-to-date evidence in a concise manner, with the help of comparison charts, algorithms, and consensus guidelines, which otherwise would require large amounts of time to cover in the vast literature. This book is unique as it is geared toward answering specific, hard clinical management questions with the most up-to-date evidence for the question or controversy at hand. In a few specific chapters, it is unable to give a strong consensus recommendation due to the lack of evidence currently available, but still presents sources of evidence for clinicians to individualize care for their patients. It does not provide textbook-type chapters that cover the whole management of a specific pathology, which makes it a great resource for advanced residents or practicing clinicians as it does require some basic knowledge to maximize its value. The book Problem Based Learning Discussions in Neuroanesthesia and Neurocritical Care, Prabhakar et al. (Springer, 2020), which shares multiple authors with this book including the editor, might be a more comprehensive and excellent addition to this book." --© Doody’s Review Service, 2021, Andres R Brenes Bastos, MD, reviewer, expert opinion"Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." --Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)

• Section A - Introduction1. Introduction to evidence-based practiceSection B - Neurophysiology2. ICP or CPP thresholds3. Role of hypothermia4. Mechanical ventilation—PEEPSection C - Neuropharmacology5. Intravenous or inhalational anesthetics?6. Hyperosmolar therapy7. Role of nitrous oxide8. Antimicrobial prophylaxis9. Role of antiepileptics10. Treatment of hypertension11. Role of statins for neuroprotection12. Role of stem cell therapy in neurosciencesSection D - Neuromonitoring13. ICP monitoring14. Type of ICP monitor15. Newer brain monitoring techniques16. Intraoperative neuromonitoringSection E - Neuromonitoring17. Blood transfusion triggers18. Reversal of anticoagulation in neurosurgical and neurocritical care settings19. Role of decompressive craniectomy20. Strategies for brain protection21. Anesthesia for carotid endarterectomy22. Anesthesia for acute stroke23. Anesthesia for spine surgerySection F - Neurointensive care24. Choice of sedation in ICU25. DVT prophylaxis26. Role of steroids27. Initiation of nutrition28. Glycemic control29. Anesthetics for status epilepticusSection G - Ethical issues30. Diagnosing brain deathSection H - Recent advances31. Simulations in clinical neurosciencesSection I - Webliography32. Webliography

Dr. Hemanshu Prabhakar is a Professor at the Department of Neuroanaesthesiology and Critical Care at the All India Institute of Medical Sciences (AIIMS), New Delhi, India. He is a recipient of the AIIMS Excellence Award 2012 for his notable contribution to academia. He has a special interest in the evidence-based practice of neuroanesthesia and ERAS. Dr. Prabhakar is a Member of various national and international neuroanesthesia societies and is the Past Secretary of the Indian Society of Neuroanesthesia and Critical Care (ISNACC) and the Society of Neurocritical Care (SNCC). He is also the Immediate Past President of the SNCC. To date, he has published more than 25 books on neuroanesthesia and neurocritical care. He is featured in the Limca Book of Records as a prolific Writer in the field of neuroanesthesiology. He actively collaborates on research activities among the low-income and middle-income countries.

"This book is a great addition to the clinical decision making in neuroanesthesiology and neurocritical care, as evidence-based practice continues to reveal its importance in clinical scenarios. This book provides up-to-date evidence in a concise manner, with the help of comparison charts, algorithms, and consensus guidelines, which otherwise would require large amounts of time to cover in the vast literature. This book is unique as it is geared toward answering specific, hard clinical management questions with the most up-to-date evidence for the question or controversy at hand. In a few specific chapters, it is unable to give a strong consensus recommendation due to the lack of evidence currently available, but still presents sources of evidence for clinicians to individualize care for their patients. It does not provide textbook-type chapters that cover the whole management of a specific pathology, which makes it a great resource for advanced residents or practicing clinicians as it does require some basic knowledge to maximize its value. The book Problem Based Learning Discussions in Neuroanesthesia and Neurocritical Care, Prabhakar et al. (Springer, 2020), which shares multiple authors with this book including the editor, might be a more comprehensive and excellent addition to this book." --© Doody’s Review Service, 2021, Andres R Brenes Bastos, MD, reviewer, expert opinion"Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." --Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)

• Section A - Introduction1. Introduction to evidence-based practiceSection B - Neurophysiology2. ICP or CPP thresholds3. Role of hypothermia4. Mechanical ventilation—PEEPSection C - Neuropharmacology5. Intravenous or inhalational anesthetics?6. Hyperosmolar therapy7. Role of nitrous oxide8. Antimicrobial prophylaxis9. Role of antiepileptics10. Treatment of hypertension11. Role of statins for neuroprotection12. Role of stem cell therapy in neurosciencesSection D - Neuromonitoring13. ICP monitoring14. Type of ICP monitor15. Newer brain monitoring techniques16. Intraoperative neuromonitoringSection E - Neuromonitoring17. Blood transfusion triggers18. Reversal of anticoagulation in neurosurgical and neurocritical care settings19. Role of decompressive craniectomy20. Strategies for brain protection21. Anesthesia for carotid endarterectomy22. Anesthesia for acute stroke23. Anesthesia for spine surgerySection F - Neurointensive care24. Choice of sedation in ICU25. DVT prophylaxis26. Role of steroids27. Initiation of nutrition28. Glycemic control29. Anesthetics for status epilepticusSection G - Ethical issues30. Diagnosing brain deathSection H - Recent advances31. Simulations in clinical neurosciencesSection I - Webliography32. Webliography