Nanomedicine-Based Approaches for the Treatment of Dementia

Dr. Umesh Gupta, currently working as Assistant Professor at Department of Pharmacy, Central University of Rajasthan, India, did his bachelor's, master's and doctorate degree in Pharmaceutical Sciences from Dr. H. S. Gour University, India under the mentorship of Prof. NK Jain. He has recently been awarded for “DAAD Research Stays for Academics and Scientists” at Leibniz-institut fur Polymerforschung Dresden, Germany. He has the past experience of Research Scientist at Ranbaxy Research Laboratories, India and Post-Doctoral Research Associate at South Dakota State University, USA. HE is also recipient of Young Scientist Award by Department of Science and Technology, Government of India as well as Ranbaxy Science Scholar Award 2008 by Ranbaxy Research Laboratories, India. He has been awarded more than 3-4 times the overseas travel award by different funding agencies of Indian government to share and present his research at international platform in countries like Germany, USA and Singapore etc. He has more than ten years of research and academic experience. The area of research is mainly focused on dendrimer mediated drug delivery, solubilization and targeting. His laboratory equally focuses on effective brain delivery through nanotechnological carriers such as polymeric micelles, nanoparticles and dendrimers. He has more than 48 publications and seven book chapters to his credit with total citations of more than 2300 (h index of 23 as per Google Scholar). Dr. Prashant Kesharwani is an Assistant Professor of Pharmaceutics at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India. His work focuses on translational nanomedicine, polymeric biomaterials, targeted drug delivery, nanoengineered drug delivery systems, and translational pharmaceutical research. He has contributed extensively to the scientific literature and has served as an editor of scholarly books. Dr. Kesharwani has received research funding from national agencies and has been recognized with awards and fellowships for his contributions to the field. His research interests include nanomedicine, targeted and stimuli-responsive drug delivery, polymeric nanocarriers, and related pharmaceutical applications. He is actively involved in scientific research, academic mentoring, and scholarly publishing.

*4 stars* "...presents an overview of the use of nanocarrier- based technologies in the treatment of different forms of dementia…. [including] the complex nature of dementia, its etiology, possible targets, and receptors, and to highlight different approaches for the treatment of this complex human disease, with an emphasis on the use of nanotechnology and nanocarriers…. The book is written for undergraduate, graduate, and doctoral students working in treating dementia via nanotechnology and drug delivery systems, as well as medical doctors interested in new ways to treat dementia and related neurodegenerative diseases…. [S]upported by color figures and illustrations, comprehensive tables, and schemes and diagrams that generate a very appealing book…. [that] succeeds, being a great addition to other similar books. Its unique approach to dementia treatment… together with nanotechnological details and the high-quality graphics make it a very useful and pleasant read." --©Doody’s Review Service, 2023, Marc A Ilies, PhD (Temple University School of Pharmacy)

• 1. Dementia and Neurodegenerative disorders: An Introduction2. Dementia: Aetiology, Types, Causes and Prevention3. Receptor attacking ligands for active targeting to Brain4. Dendrimer based drug delivery for Dementia5. Polymeric nanoparticles-based drug delivery for Dementia6. Solid lipid nanoparticles (SLN) based drug delivery for Dementia7. Liposomes based drug delivery for Dementia8. Micelles based drug delivery for Dementia9. Quantum dots-based drug delivery for Dementia10. Nanocarrier based non-invasive approaches for Dementia11. Futuristic aspect of nanocarriers on targeted delivery for dementia