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Beskrivning
This book presents the biochemical and molecular biological fundamentals underlying toxicology and drug metabolism. It covers xenobiotic biotransformation; reactive intermediates and their interactions with macromolecules; cloning, expressiong, and analysis of enzymes of biotransformation; and molecular toxicology of aromatic amines, nirosamines, polycyclic aromatic hydrocarbons, chlorinated compounds.
P. David Josephy is Professor of Molecular and Cellular Biology at the University of Guelph. Bengt Mannervik is the Karin and Herbert Jacobsson Professor of Biochemistry at Uppsala University, Sweden.