Harris A. Eyre, MBBS PhD, is a Brain Health Venture Executive, Diplomat and Author. He is President and Chief Medical Officer of Prodeo, which specializes in the commercialization of brain health technologies. Harris is focus on catalyzing transformational change in the brain health sector by leveraging frontier technologies, entrepreneurship, responsible innovation, convergence science and diplomacy.Michael Berk is an NHMRC Senior Principal Research Fellow at Deakin University, where he heads the IMPACT institute. He is listed by Thompson Reuters as amongst the world's most influential scientific minds (2015-2019) and was awarded the Brain & Behaviour (NARSAD) Colvin Award for Mood Disorders in 2015 and the Victoria Prize for life sciences in 2019. He is past president of the International Society for Bipolar Disorders and the Australasian Society for Bipolar and Depressive Disorders. His major interests are in the discovery and implementation of novel therapies.Helen Lavretsky, MD, MS is a professor of Psychiatry and Biobehavioral Sciences at the Jane and Terry Semel Institute and the Department of Psychiatry at UCLA. She directs the Integrative psychiatry research and clinical program. She is a geriatric and integrative psychiatrist with a research program in novel treatments for geriatric depression and integrative mental health using mind-body interventions. She is also a Distinguished Fellow of the American Psychiatric Association and a Fellow of the American College of Neuropsychopharmacology. She is the recipient of the 2020 Jack Weinberg APA award for career in geriatric psychiatry and the American College of Psychiatrists research award in geriatric psychiatry.Charles F. Reynolds III, MD, is a NIH-sponsored physician-scientist addressing prevention and treatment of depression in older adults in primary care and specialty mental health settings, in high-, middle-,and low-income countries. Recipient of the 2016 Brain and Behavior Research Foundation Herbert Pardes Humanitarian Prize in Mental Health; and of an NIMH MERIT award and Research Scientist Award. Elected member, Association of American Physicians. Editor-in-Chief: American Journal of Geriatric Psychiatry. Previous service on three Institute of Medicine study panels and on the NIMH National Advisory Mental Health Council; and past President of the American College of Psychiatrists, the American Foundation for Suicide Prevention, and the American Association for Geriatric Psychiatry.

Mental health conditions are a key contributor to the global burden of disease and disability. The devastating impact of these conditions is even more apparent as the world faces global challenges such as the COVID-19 pandemic, climate change, societal inequity, and more. At the same time, the human brain, thought, and behavior are the most complex objects of human science. To make progress, we need a fundamental shift in our approach. Convergence science, which integrates expertise from diverse fields to form comprehensive frameworks to address specific challenges, holds promise for tackling the global mental health crisis. Convergence Mental Health deftly makes the case that a convergence approach is urgently needed to tackle the global mental health crisis and provides a roadmap for change."

• Framing Definitions 1. Leveraging Convergence Science to Address Global Mental Health Challenges 2. On the road to convergence research: scientists reaching across disciplines to tackle tough problems. 3. Convergence and the Changing Nature of Innovation 4. Developing Convergence Neuroscience as a Model 5. Establishing Transdisciplinarity within a University: Learning from the Experience of the University of Technology Sydney 6. The Therapeutic Centaur: Training the half-human, half-computer clinician of 2040 7. Update on the War on Mental Illness: Perspectives on Translational Psychiatry 8. Promoting early child development: using convergence science for the scalable assessment and monitoring of cognitive development 9. Artificial Intelligence in Mental Health 10. Precision Mental Health: Focus on Depression 11. Emerging Role for Technology in Positive Psychiatry Interventions: Importance of Convergence Medicine in Improving Mental Well-being 12. A Social, Behavioral and Implementation Science Perspective on Convergence Mental Health 13. Convergence Mental Health Across the Life Span: Advances in Precision Geriatric Psychiatry 14. Convergence Neuroscience of Meditative Mind-Body Therapies for Mental Health 15. The use of bioinformatics and big data for the in silico study of psychiatric disorders 16. Converging technologies between the Space Mars Mission and Earth Global Mental Health 17. Innovation Diplomacy in the Clinical Neurosciences 18. Towards Multi-Omic Informed Psychotropic Prescribing 19. Biobehavioral Sensing for Objective Evaluation of OCD Patients 20. An Introduction to Antidepressant Pharmacomicrobiomics and Implications in Depression 21. Blockchain for Convergence Science in Mental Health 22. Global Mental Health and Technology: Examples of the Asia-Pacific Economic Cooperation Digital Hub for Mental Health and the Enhanced Measurement-Based care Effectiveness in Depression 23. Digital Health Entrepreneurship: A Convergent Discipline for Mental Health24.Stanford's Brainstorm Lab for Mental Health Innovation 25. Innovating dementia care through convergence science in brain health: UCSF Memory Aging Center as a case example 26. NODE.Health Algorithm to Support Digital Mental Health Validation 27. Key Considerations for Developing Digital Health Accelerators 28. Screening for Convergent Practitioners in Health Research and Innovation: The Role of a High Potential Personality 29. The Minds Behind the Technology: Lessons on Entrepreneurial Mental Health 30. Consumer participation in personalized psychiatry: 31. Collaborative Research and Investment to Secure <"Healthy Brains for All> ": A Selection of One Mind Projects 32. Unconventional Approaches to Investing in Mental Health Technology 33. Convergence Mental Health: Barriers, Solutions, and Actionable Avenues for Philanthropic Investment 34. Trans-sectorial neuroscience innovation for the 21st century: the BrainMind model 35. A Roadmap Towards Convergence Mental Health: Overcoming Barriers from Research, to Initial Commercialization, to Scaling Up Market Penetration

Harris A. Eyre, MBBS PhD, is a Brain Health Venture Executive, Diplomat and Author. He is President and Chief Medical Officer of Prodeo, which specializes in the commercialization of brain health technologies. Harris is focus on catalyzing transformational change in the brain health sector by leveraging frontier technologies, entrepreneurship, responsible innovation, convergence science and diplomacy.Michael Berk is an NHMRC Senior Principal Research Fellow at Deakin University, where he heads the IMPACT institute. He is listed by Thompson Reuters as amongst the world's most influential scientific minds (2015-2019) and was awarded the Brain & Behaviour (NARSAD) Colvin Award for Mood Disorders in 2015 and the Victoria Prize for life sciences in 2019. He is past president of the International Society for Bipolar Disorders and the Australasian Society for Bipolar and Depressive Disorders. His major interests are in the discovery and implementation of novel therapies.Helen Lavretsky, MD, MS is a professor of Psychiatry and Biobehavioral Sciences at the Jane and Terry Semel Institute and the Department of Psychiatry at UCLA. She directs the Integrative psychiatry research and clinical program. She is a geriatric and integrative psychiatrist with a research program in novel treatments for geriatric depression and integrative mental health using mind-body interventions. She is also a Distinguished Fellow of the American Psychiatric Association and a Fellow of the American College of Neuropsychopharmacology. She is the recipient of the 2020 Jack Weinberg APA award for career in geriatric psychiatry and the American College of Psychiatrists research award in geriatric psychiatry.Charles F. Reynolds III, MD, is a NIH-sponsored physician-scientist addressing prevention and treatment of depression in older adults in primary care and specialty mental health settings, in high-, middle-,and low-income countries. Recipient of the 2016 Brain and Behavior Research Foundation Herbert Pardes Humanitarian Prize in Mental Health; and of an NIMH MERIT award and Research Scientist Award. Elected member, Association of American Physicians. Editor-in-Chief: American Journal of Geriatric Psychiatry. Previous service on three Institute of Medicine study panels and on the NIMH National Advisory Mental Health Council; and past President of the American College of Psychiatrists, the American Foundation for Suicide Prevention, and the American Association for Geriatric Psychiatry.

Mental health conditions are a key contributor to the global burden of disease and disability. The devastating impact of these conditions is even more apparent as the world faces global challenges such as the COVID-19 pandemic, climate change, societal inequity, and more. At the same time, the human brain, thought, and behavior are the most complex objects of human science. To make progress, we need a fundamental shift in our approach. Convergence science, which integrates expertise from diverse fields to form comprehensive frameworks to address specific challenges, holds promise for tackling the global mental health crisis. Convergence Mental Health deftly makes the case that a convergence approach is urgently needed to tackle the global mental health crisis and provides a roadmap for change."

• Framing Definitions 1. Leveraging Convergence Science to Address Global Mental Health Challenges 2. On the road to convergence research: scientists reaching across disciplines to tackle tough problems. 3. Convergence and the Changing Nature of Innovation 4. Developing Convergence Neuroscience as a Model 5. Establishing Transdisciplinarity within a University: Learning from the Experience of the University of Technology Sydney 6. The Therapeutic Centaur: Training the half-human, half-computer clinician of 2040 7. Update on the War on Mental Illness: Perspectives on Translational Psychiatry 8. Promoting early child development: using convergence science for the scalable assessment and monitoring of cognitive development 9. Artificial Intelligence in Mental Health 10. Precision Mental Health: Focus on Depression 11. Emerging Role for Technology in Positive Psychiatry Interventions: Importance of Convergence Medicine in Improving Mental Well-being 12. A Social, Behavioral and Implementation Science Perspective on Convergence Mental Health 13. Convergence Mental Health Across the Life Span: Advances in Precision Geriatric Psychiatry 14. Convergence Neuroscience of Meditative Mind-Body Therapies for Mental Health 15. The use of bioinformatics and big data for the in silico study of psychiatric disorders 16. Converging technologies between the Space Mars Mission and Earth Global Mental Health 17. Innovation Diplomacy in the Clinical Neurosciences 18. Towards Multi-Omic Informed Psychotropic Prescribing 19. Biobehavioral Sensing for Objective Evaluation of OCD Patients 20. An Introduction to Antidepressant Pharmacomicrobiomics and Implications in Depression 21. Blockchain for Convergence Science in Mental Health 22. Global Mental Health and Technology: Examples of the Asia-Pacific Economic Cooperation Digital Hub for Mental Health and the Enhanced Measurement-Based care Effectiveness in Depression 23. Digital Health Entrepreneurship: A Convergent Discipline for Mental Health24.Stanford's Brainstorm Lab for Mental Health Innovation 25. Innovating dementia care through convergence science in brain health: UCSF Memory Aging Center as a case example 26. NODE.Health Algorithm to Support Digital Mental Health Validation 27. Key Considerations for Developing Digital Health Accelerators 28. Screening for Convergent Practitioners in Health Research and Innovation: The Role of a High Potential Personality 29. The Minds Behind the Technology: Lessons on Entrepreneurial Mental Health 30. Consumer participation in personalized psychiatry: 31. Collaborative Research and Investment to Secure <"Healthy Brains for All> ": A Selection of One Mind Projects 32. Unconventional Approaches to Investing in Mental Health Technology 33. Convergence Mental Health: Barriers, Solutions, and Actionable Avenues for Philanthropic Investment 34. Trans-sectorial neuroscience innovation for the 21st century: the BrainMind model 35. A Roadmap Towards Convergence Mental Health: Overcoming Barriers from Research, to Initial Commercialization, to Scaling Up Market Penetration