Zelalem Temesgen, MD, is a professor of medicine and a consultant in the Division of Infectious Diseases at Mayo Clinic in Rochester, Minnesota. He established the HIV Clinic at Mayo Clinic and is currently the director of the HIV program as well as the director of the Mayo Clinic Global HIV Education Initiative. Dr. Temesgen is board certified in infectious diseases and is certified as an HIV specialist by the American Academy of HIV Medicine. In addition to his clinical duties, Dr Temesgen is actively involved in education both within Mayo Clinic and extramurally. His educational activities include media presentations, extramural visiting professorships, and invited lectures at national and international meetings.

• Table of Contents ; Section I: General ; 1 Pharmacokinetics and Pharmacodynamics of Antimicrobials Lynn L. Estes, PharmD, RPh ; 2 Antimicrobials Lynn L. Estes, PharmD, RPh, and John W. Wilson, MD ; 3 Health Care-Associated Infection Prevention and Control Programs W. Charles Huskins, MD ; 4 Mycobacterial and Fungal Diagnostic Matthew J. Binnicker, PhD, Glenn D. Roberts, PhD, and Nancy L. Wengenack, PhD ; Questions and Answers ; Section II: Etiologic Agents ; 5 Select Viruses in Adults Randall C. Walker, MD ; 6 Select Gram-positive Aerobic Bacteria Robin Patel, MD ; 7 Select Gram-negative Aerobic Bacteria David R. McNamara, MD, and Franklin R. Cockerill III, MD ; 8 Select Anerobic Bacteria: Clostridium tetani and Clostridium botulinum M. Rizwan Sohail, MD ; 9 Borrelia and Leptospira Species Julio C. Mendez, MD ; 10 Tick-Borne Infections Alan J. Wright, MD ; 11 Mycobacteria Irene G. Sia, MD ; 12 Nocardia and Actinomyces Christine L. Terrell, MD ; 13 Candida Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 14 Aspergillus Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 15 Histoplasma capsulatum Janis E. Blair, MD ; 16 Blastomyces dermatitidis Janis E. Blair, MD ; 17 Coccidioides Species Janis E. Blair, MD ; 18 Paracoccidioides brasiliensis Janis E. Blair, MD ; 19 Sporothrix schenckii Janis E. Blair, MD ; 20 Cryptococcus neoformans Shimon Kusne, MD, and Ann E. McCullough, MD ; 21 Emerging Fungal Infections Holenarasipur R. Vikram, MD, FACP, FIDSA ; 22 Parasitic Infections Jon E. Rosenblatt, MD, and Bobbi S. Pritt, MD ; Questions and Answers ; Section III: Select Major Clinical Syndromes ; 23 Fever of Unknown Origin Mary J. Kasten, MD ; 24 Infections of the Oral Cavity, Neck, and Head Lisa M. Brumble, MD ; 25 Pneumonia Priya Sampathkumar, MD ; 26 Urinary Tract Infections Walter C. Hellinger, MD ; 27 Sepsis Syndrome Andrew D. Badley, MD ; 28 Infectious Diarrhea Robert Orenstein, DO ; 29 Intra-abdominal Infections Robert Orenstein, DO ; 30 Viral Hepatitis Stacey A. Rizza, MD ; 31 Infective Endocarditis Larry M. Baddour, MD, and Daniel Z. Uslan, MD ; 32 Infections of the Central Nervous System Michael R. Keating, MD ; 33 Skin and Soft Tissue Infections Imad M. Tleyjeh, MD, MSc, and Larry M. Baddour, MD ; 34 Osteomyelitis, Infectious Arthritis, and Orthopedic Device Infection Elie F. Berbari, MD, and Douglas R. Osmon, MD ; 35 Sexually Transmitted Diseases Randall S. Edson, MD ; Questions and Answers ; Section IV: Special Hosts and Situations ; 36 Human Immunodeficiency Virus Infection Zelalem Temesgen, MD ; 37 HIV-Associated Opportunistic Infections and Conditions Anne M. Meehan, MB, BCh, PhD, and Eric M. Poeschla, MD ; 38 Infections in Patients With Hematologic Malignancies John W. Wilson, MD, and Michelle A. Elliott, MD ; 39 Infections in Transplant Recipients Raymund R. Razonable, MD ; 40 Health Care-Associated Infections Rodney L. Thompson, MD, and Priya Sampathkumar, MD ; 41 Obstetric and Gynecologic Issues Related to Infectious Diseases Kristi L. Boldt, MD ; 42 Pediatric Infectious Diseases Thomas G. Boyce, MD ; 43 Travel Medicine Abinash Virk, MD ; 44 Adult Immunizations Priya Sampathkumar, MD ; 45 Agents of Bioterrorism Mark P. Wilhelm, MD, FACP ; Questions and Answers

Zelalem Temesgen, MD, is a professor of medicine and a consultant in the Division of Infectious Diseases at Mayo Clinic in Rochester, Minnesota. He established the HIV Clinic at Mayo Clinic and is currently the director of the HIV program as well as the director of the Mayo Clinic Global HIV Education Initiative. Dr. Temesgen is board certified in infectious diseases and is certified as an HIV specialist by the American Academy of HIV Medicine. In addition to his clinical duties, Dr Temesgen is actively involved in education both within Mayo Clinic and extramurally. His educational activities include media presentations, extramural visiting professorships, and invited lectures at national and international meetings.

• Table of Contents ; Section I: General ; 1 Pharmacokinetics and Pharmacodynamics of Antimicrobials Lynn L. Estes, PharmD, RPh ; 2 Antimicrobials Lynn L. Estes, PharmD, RPh, and John W. Wilson, MD ; 3 Health Care-Associated Infection Prevention and Control Programs W. Charles Huskins, MD ; 4 Mycobacterial and Fungal Diagnostic Matthew J. Binnicker, PhD, Glenn D. Roberts, PhD, and Nancy L. Wengenack, PhD ; Questions and Answers ; Section II: Etiologic Agents ; 5 Select Viruses in Adults Randall C. Walker, MD ; 6 Select Gram-positive Aerobic Bacteria Robin Patel, MD ; 7 Select Gram-negative Aerobic Bacteria David R. McNamara, MD, and Franklin R. Cockerill III, MD ; 8 Select Anerobic Bacteria: Clostridium tetani and Clostridium botulinum M. Rizwan Sohail, MD ; 9 Borrelia and Leptospira Species Julio C. Mendez, MD ; 10 Tick-Borne Infections Alan J. Wright, MD ; 11 Mycobacteria Irene G. Sia, MD ; 12 Nocardia and Actinomyces Christine L. Terrell, MD ; 13 Candida Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 14 Aspergillus Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 15 Histoplasma capsulatum Janis E. Blair, MD ; 16 Blastomyces dermatitidis Janis E. Blair, MD ; 17 Coccidioides Species Janis E. Blair, MD ; 18 Paracoccidioides brasiliensis Janis E. Blair, MD ; 19 Sporothrix schenckii Janis E. Blair, MD ; 20 Cryptococcus neoformans Shimon Kusne, MD, and Ann E. McCullough, MD ; 21 Emerging Fungal Infections Holenarasipur R. Vikram, MD, FACP, FIDSA ; 22 Parasitic Infections Jon E. Rosenblatt, MD, and Bobbi S. Pritt, MD ; Questions and Answers ; Section III: Select Major Clinical Syndromes ; 23 Fever of Unknown Origin Mary J. Kasten, MD ; 24 Infections of the Oral Cavity, Neck, and Head Lisa M. Brumble, MD ; 25 Pneumonia Priya Sampathkumar, MD ; 26 Urinary Tract Infections Walter C. Hellinger, MD ; 27 Sepsis Syndrome Andrew D. Badley, MD ; 28 Infectious Diarrhea Robert Orenstein, DO ; 29 Intra-abdominal Infections Robert Orenstein, DO ; 30 Viral Hepatitis Stacey A. Rizza, MD ; 31 Infective Endocarditis Larry M. Baddour, MD, and Daniel Z. Uslan, MD ; 32 Infections of the Central Nervous System Michael R. Keating, MD ; 33 Skin and Soft Tissue Infections Imad M. Tleyjeh, MD, MSc, and Larry M. Baddour, MD ; 34 Osteomyelitis, Infectious Arthritis, and Orthopedic Device Infection Elie F. Berbari, MD, and Douglas R. Osmon, MD ; 35 Sexually Transmitted Diseases Randall S. Edson, MD ; Questions and Answers ; Section IV: Special Hosts and Situations ; 36 Human Immunodeficiency Virus Infection Zelalem Temesgen, MD ; 37 HIV-Associated Opportunistic Infections and Conditions Anne M. Meehan, MB, BCh, PhD, and Eric M. Poeschla, MD ; 38 Infections in Patients With Hematologic Malignancies John W. Wilson, MD, and Michelle A. Elliott, MD ; 39 Infections in Transplant Recipients Raymund R. Razonable, MD ; 40 Health Care-Associated Infections Rodney L. Thompson, MD, and Priya Sampathkumar, MD ; 41 Obstetric and Gynecologic Issues Related to Infectious Diseases Kristi L. Boldt, MD ; 42 Pediatric Infectious Diseases Thomas G. Boyce, MD ; 43 Travel Medicine Abinash Virk, MD ; 44 Adult Immunizations Priya Sampathkumar, MD ; 45 Agents of Bioterrorism Mark P. Wilhelm, MD, FACP ; Questions and Answers

Zelalem Temesgen, MD, is a professor of medicine and a consultant in the Division of Infectious Diseases at Mayo Clinic in Rochester, Minnesota. He established the HIV Clinic at Mayo Clinic and is currently the director of the HIV program as well as the director of the Mayo Clinic Global HIV Education Initiative. Dr. Temesgen is board certified in infectious diseases and is certified as an HIV specialist by the American Academy of HIV Medicine. In addition to his clinical duties, Dr Temesgen is actively involved in education both within Mayo Clinic and extramurally. His educational activities include media presentations, extramural visiting professorships, and invited lectures at national and international meetings.

• Table of Contents ; Section I: General ; 1 Pharmacokinetics and Pharmacodynamics of Antimicrobials Lynn L. Estes, PharmD, RPh ; 2 Antimicrobials Lynn L. Estes, PharmD, RPh, and John W. Wilson, MD ; 3 Health Care-Associated Infection Prevention and Control Programs W. Charles Huskins, MD ; 4 Mycobacterial and Fungal Diagnostic Matthew J. Binnicker, PhD, Glenn D. Roberts, PhD, and Nancy L. Wengenack, PhD ; Questions and Answers ; Section II: Etiologic Agents ; 5 Select Viruses in Adults Randall C. Walker, MD ; 6 Select Gram-positive Aerobic Bacteria Robin Patel, MD ; 7 Select Gram-negative Aerobic Bacteria David R. McNamara, MD, and Franklin R. Cockerill III, MD ; 8 Select Anerobic Bacteria: Clostridium tetani and Clostridium botulinum M. Rizwan Sohail, MD ; 9 Borrelia and Leptospira Species Julio C. Mendez, MD ; 10 Tick-Borne Infections Alan J. Wright, MD ; 11 Mycobacteria Irene G. Sia, MD ; 12 Nocardia and Actinomyces Christine L. Terrell, MD ; 13 Candida Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 14 Aspergillus Species Shimon Kusne, MD, and Ann E. McCullough, MD ; 15 Histoplasma capsulatum Janis E. Blair, MD ; 16 Blastomyces dermatitidis Janis E. Blair, MD ; 17 Coccidioides Species Janis E. Blair, MD ; 18 Paracoccidioides brasiliensis Janis E. Blair, MD ; 19 Sporothrix schenckii Janis E. Blair, MD ; 20 Cryptococcus neoformans Shimon Kusne, MD, and Ann E. McCullough, MD ; 21 Emerging Fungal Infections Holenarasipur R. Vikram, MD, FACP, FIDSA ; 22 Parasitic Infections Jon E. Rosenblatt, MD, and Bobbi S. Pritt, MD ; Questions and Answers ; Section III: Select Major Clinical Syndromes ; 23 Fever of Unknown Origin Mary J. Kasten, MD ; 24 Infections of the Oral Cavity, Neck, and Head Lisa M. Brumble, MD ; 25 Pneumonia Priya Sampathkumar, MD ; 26 Urinary Tract Infections Walter C. Hellinger, MD ; 27 Sepsis Syndrome Andrew D. Badley, MD ; 28 Infectious Diarrhea Robert Orenstein, DO ; 29 Intra-abdominal Infections Robert Orenstein, DO ; 30 Viral Hepatitis Stacey A. Rizza, MD ; 31 Infective Endocarditis Larry M. Baddour, MD, and Daniel Z. Uslan, MD ; 32 Infections of the Central Nervous System Michael R. Keating, MD ; 33 Skin and Soft Tissue Infections Imad M. Tleyjeh, MD, MSc, and Larry M. Baddour, MD ; 34 Osteomyelitis, Infectious Arthritis, and Orthopedic Device Infection Elie F. Berbari, MD, and Douglas R. Osmon, MD ; 35 Sexually Transmitted Diseases Randall S. Edson, MD ; Questions and Answers ; Section IV: Special Hosts and Situations ; 36 Human Immunodeficiency Virus Infection Zelalem Temesgen, MD ; 37 HIV-Associated Opportunistic Infections and Conditions Anne M. Meehan, MB, BCh, PhD, and Eric M. Poeschla, MD ; 38 Infections in Patients With Hematologic Malignancies John W. Wilson, MD, and Michelle A. Elliott, MD ; 39 Infections in Transplant Recipients Raymund R. Razonable, MD ; 40 Health Care-Associated Infections Rodney L. Thompson, MD, and Priya Sampathkumar, MD ; 41 Obstetric and Gynecologic Issues Related to Infectious Diseases Kristi L. Boldt, MD ; 42 Pediatric Infectious Diseases Thomas G. Boyce, MD ; 43 Travel Medicine Abinash Virk, MD ; 44 Adult Immunizations Priya Sampathkumar, MD ; 45 Agents of Bioterrorism Mark P. Wilhelm, MD, FACP ; Questions and Answers