Covid-19: Biomedical Perspectives

Dr. Pavia is a Microbiologist/Immunologist and an Associate Professor at the NYIT College of Osteopathic Medicine in Old Westbury, New York. He is also an Adjunct Associate Professor at New York Medical College. He previously worked and held research appointments at the Trudeau Institute in Saranac Lake, NY, and the Walter Reed Army Institute for Research in Washington, DC. Throughout his career, he has focused his research activities on various pathogenic microbes with a particular emphasis on the disease-causing spirochetes and certain protozoan pathogens. His research has covered multiple areas including the basic microbiologic, immunologic, molecular, diagnostic and clinical aspects of Lyme disease, syphilis, malaria and toxoplasmosis. He has published widely on these areas in peer-reviewed journals, as well as given numerous research presentations of his work at national and international conferences. As a principal investigator or co-investigator, he has received research funding from the NIH, the CDC, the J.M. Foundation, and various other organizations to support his research work. He has been a member of the editorial board of the Journal of Microbiological Methods for the past 25 years, and has been an ad-hoc reviewer for a wide range of other scientific journals. Dr Gurtler completed a Ph.D. program in 1996 at La Trobe University in the Department of Microbiology. The main contribution of this work was the development of a universal bacterial typing technique based on the 16S-23S rDNA spacer region. The technique is now extensively used in many areas of Microbiology including Diagnostic, Environmental and Veterinary Microbiology. Citations to the articles Dr Gurtler wrote on this topic total >1000 with >830 citations alone to the 1996 review published in the journal “Microbiology”. Dr Gurtler wrote an invited review on genomic typing, taxonomy and identification of bacterial isolates for the International Journal of Systematic and Evolutionary Microbiology (IJSEM). In addition to fundamental research, Dr Gurtler has also had experience with the application of this technology to the medical diagnostic laboratory in the fields of molecular microbiology and human molecular genetics. Dr Gurtler has been involved full time in diagnostic microbiology over many years resulting in the adoption of a method that identifies Mycobacterium species directly from clinical specimens without the need for culture in specimens positive for acid fast bacilli, the discovery of Nocardia veterana, and the development of many diagnostic tests.In the last twelve years Dr Gurtler has been an Editor for the Journal of Microbiological Methods (JMM) and in the last 5 years Serial Editor of Methods in Microbiology (MIM) with the publication of 9 volumes covering diverse subjects such as Biofilms, Nanotechnology, COVID-19 and Fluorescent Probes.

• PrefaceVolker Gűrtler and Charles Pavia1. Sensitive methods for detection of SARS-CoV-2 RNAXi Chen and Simin Xia2. Treatment of COVID-19 using Chinese herbal medicineWilliam Cho3. Understanding how SARS-CoV-2 is evolving and its impact on COVID-19 animal models and vaccine evaluationSeshadri S. Vasan4. Methods in machine learning to identify COVID-19 literatureAnhvinh Doanvo5. COVID-19 seasonal behavior and the mutational landscape of the SARS-CoV-2 virusGustavo Caetano-Anolles6. Afsar Raza Naqvi7. CRISPR use in Diagnosis and Therapy for COVID-19Yashpal Singh Malik, Pallavi Deol and Rahul Kaushik8. Kuldeep Dhama9. Recent and advanced nanotechnological strategies for COVID-19 vaccine development Chinekwu Sherridan Nwagwu10. A review of hypersensitivity methods to measure cellular immune responses to SARS-CoV-2Victor Matheu and Yvelise Barrios11. Role of mRNA technology and gene silencing in manufacturing vaccines against SARS-CoV-2Pratik Talukder12. Hesitancy to get vaccinated against COVID-19 and how it might be overcomeCharles Pavia