Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part A

Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.

• 1. An introduction and use of the CRISPR-Cas systemsVijai Singh 2. History, evolution and classification of CRISPR-Cas associated systemsNisheeth Agarwal and Radhika Gupta 3. CRISPR based bacterial genome editing and removal of pathogensRavi Jothi, Chandrasekar Karthika, Arumugam Kamaladevi, Lakkakula Satish, Shunmugiah Karutha Pandian and Shanmugaraj Gowrishankar 4. CRISPR based genome editing and removal of human virusesYuan-Chuan Chen 5. CRISPR based development of RNA editing and the diagnostic platformLakkakula Satish, Gunamalai Lavanya, Thirupathi Kasthuri, Aruchamy Kalaivaani, Sasanala Shamili, Muthuramalingam Pandian, Shanmugaraj Gowrishankar, Shunmugiah Karutha Pandian, Vijai Singh, Yaron Sitrit and Ariel Kushmaro 6. CRISPR-based pathogenic fungal genome editing for control of infection and diseaseTakayuki Arazoe 7. Genome engineering in insects for the control of vector borne diseasesV. Edwin Hillary and S. Antony Ceasar