Diagnostic Pathology: Cytopathology

Michael J. Thrall, MD, is a pathologist with the Department of Pathology and Genomic Medicine at Houston Methodist Hospital in Houston, Texas. He is Professor of Pathology and Laboratory Medicine with Weill Cornell Medicine at Cornell University in New York, New York.

"This book is from the Elsevier Diagnostic Pathology series. In this particular volume, the series' characteristic high-yield and image-rich formatting is applied to the wide array of specimen types encountered in all realms of cytopathology."-- ©Doody’s Review Service, 2023, Madelyn Lew, M.D. (University of Michigan Medical School) Doody's Score: 5 Stars!

• Part I: Gynecologic CytopathologySECTION 1: OVERVIEW4 Pap Test and Cervical Cancer Screening: History and Reporting TerminologyNikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD8 Cytopreparation, Instrumentation, and Automated Screening in Gynecologic CytologyMichael J. Thrall, MD and Debora A. Smith, CT(ASCP)10 Specimen Adequacy in Cervicovaginal CytologyDina R. Mody, MD and George G. Birdsong, MDSECTION 2: BENIGN AND INFECTIOUS CONDITIONS14 Normal Pap Test Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD16 Infectious and Other Organisms in Pap Tests Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD18 Nonneoplastic Findings, Mimics, and ArtifactsEkene I. Okoye, MD and Dina R. Mody, MDSECTION 3: SQUAMOUS CELLABNORMALITIES AND MIMICS28 Low-Grade Squamous Intraepithelial Lesion and MimicsDina R. Mody, MD30 High-Grade Squamous Intraepithelial Lesion and MimicsDina R. Mody, MD and Ekene I. Okoye, MD34 Atypical Squamous Cells of Undetermined SignificanceNikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD36 Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial LesionDina R. Mody, MD and Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC38 Squamous Cell Carcinoma of Cervix, Variants and MimicsDina R. Mody, MD46 Endocervical Adenocarcinoma In Situ, Variants and MimicsDina R. Mody, MD52 Endocervical Adenocarcinoma, Variants and MimicsDina R. Mody, MD56 Adenocarcinoma, Gastric TypeDina R. Mody, MD58 Endometrial Cancers: Usual Types, Variants, and MimicsEkene I. Okoye, MD and Dina R. Mody, MD64 Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOSDina R. Mody, MD70 Endometrial Cells in Pap Test and Glandular Cells Status Post HysterectomyDina R. Mody, MD and Ekene I. Okoye, MD74 Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology Dina R. Mody, MD 76 Neuroendocrine Carcinoma of Cervix Dina R. Mody, MD 78 Other Uncommon Malignancies in Cervicovaginal Cytology Dina R. Mody, MD 84 HPV and Other Molecular Testing in Gynecologic CytologyMichael J. Thrall, MD90 Directly Sampled Endometrial CytologyYuko Sugiyama, MD, PhD, FIAC and Dina R. Mody, MD96 Anal CytologyMichael J. Thrall, MDPart II: Exfoliative CytopathologySpecimen Types in Respiratory Cytology and Adequacy CriteriaMichael J. Thrall, MD102 Benign and Reactive ChangesMichael J. Thrall, MD106 PneumocystisPneumonia and MimicsMichael J. Thrall, MD108 Fungal Organisms in Respiratory CytologyMichael J. Thrall, MDParasitic Organisms in Respiratory CytologyMichael J. Thrall, MD112 Viral Infections (Cytomegalovirus, Herpesvirus, and Others)Michael J. Thrall, MD114 Mycobacteria and Other Bacterial InfectionsMichael J. Thrall, MD116 Sarcoidosis and Other Immune-Related ConditionsMichael J. Thrall, MD118 Pulmonary Alveolar Proteinosis and MimicsMichael J. Thrall, MDMiscellaneous Findings, Including ContaminantsMichael J. Thrall, MD122 AdenocarcinomaMichael J. Thrall, MD126 Squamous Cell CarcinomaMichael J. Thrall, MD128 Small Cell CarcinomaMichael J. Thrall, MDLarge Cell Neuroendocrine CarcinomaMichael J. Thrall, MD132 Carcinoid and Atypical CarcinoidMichael J. Thrall, MD134 Rare Benign and Low Malignant Potential TumorsMichael J. Thrall, MD136 Rare Malignant TumorsMichael J. Thrall, MD138 NUT CarcinomaMichael J. Thrall, MD139 SMARCA4-Deficient Undifferentiated TumorMichael J. Thrall, MDPulmonary LymphomaMichael J. Thrall, MD142 Pulmonary MetastasisMichael J. Thrall, MD146 Specimen Types in Gastrointestinal Cytology and Normal Cellular ComponentsBlythe K. Gorman, MD148 Parasitic InfectionsBlythe K. Gorman, MDViral InfectionsBlythe K. Gorman, MD152 Esophagitis and Barrett EsophagusBlythe K. Gorman, MD154 Esophageal AdenocarcinomaBlythe K. Gorman, MD156 Esophageal Squamous Cell CarcinomaBlythe K. Gorman, MD158 Gastritis and Intestinal MetaplasiaBlythe K. Gorman, MDGastric AdenocarcinomaBlythe K. Gorman, MD162 Gastric LymphomaBlythe K. Gorman, MD164 Ampulla/Bile Duct/Pancreatic Duct Reactive ChangesBlythe K. Gorman, MD166 Ampulla/Bile Duct/Pancreatic Duct AdenocarcinomaBlythe K. Gorman, MD168 Colorectal Adenoma/CarcinomaBlythe K. Gorman, MDNeuroendocrine Tumor/CarcinomaBlythe K. Gorman, MD172 Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal TumorsBlythe K. Gorman, MD176 Normal Cerebrospinal Fluid and Contamination by Normal ElementsHidehiro Takei, MDInfectious MeningitisHidehiro Takei, MD182 Aseptic and Mollaret MeningitisHidehiro Takei, MD184 Subarachnoid HemorrhageHidehiro Takei, MD186 Neurodegenerative DiseasesHidehiro Takei, MD188 Primary Brain TumorsHidehiro Takei, MDLeukemia and LymphomaHidehiro Takei, MD192 Metastasis in Cerebrospinal FluidHidehiro Takei, MD196 Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting TerminologyDonna M. Coffey, MD and Michael J. Thrall, MDInfectious ConditionsDonna M. Coffey, MD and Michael J. Thrall, MD202 Autoimmune DiseasesDonna M. Coffey, MD and Michael J. Thrall, MD204 Malignant Effusion, Mesothelioma208 Malignant Effusion, Carcinomas 212 Malignant Effusion, SarcomasDonna M. Coffey, MD, Nour Sneige, MD, and Michael J. Thrall, MD214 Lymphoid Effusions and LymphomasDonna M. Coffey, MD and Michael J. Thrall, MD216 Primary Effusion LymphomaJohn M. Stewart, MD, PhD and Michael J. Thrall, MD218 Endometriosis and EndosalpingiosisDonna M. Coffey, MD, Nour Sneige, MD, and Michael J. Thrall, MD220 Ovarian NeoplasmsDonna M. Coffey, MD and Michael J. Thrall, MD222 Immunocytochemistry, Histochemistry, and Other Ancillary TechniquesDonna M. Coffey, MD and Michael J. Thrall, MD228 Normal Urinary Cytology, Specimen Types, and Reporting TerminologyMichael J. Thrall, MD and Rose Anton, MD232 Ileal Conduit SpecimensRose Anton, MD and Michael J. Thrall, MD234 Noninfectious Benign ConditionsRose Anton, MD and Michael J. Thrall, MD236 Infectious Benign ConditionsRose Anton, MD and Michael J. Thrall, MD238 Reactive Urothelial ChangesRose Anton, MD and Michael J. Thrall, MD240 Low-Grade Urothelial LesionsRose Anton, MD and Michael J. Thrall, MD241 Atypical Urothelial CellsMichael J. Thrall, MD242 High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In SituRose Anton, MD and Michael J. Thrall, MD244 Squamous Cell Carcinoma of Urinary BladderRose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD246 Adenocarcinoma of Urinary BladderRose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD248 Other Malignancies in Urinary CytologyRose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD250 Renal Pelvic CytologyBlythe K. Gorman, MD and Michael J. Thrall, MD252 Ancillary Testing, UroVysion, and OthersGene Landon, MD, Nancy P. Caraway, MD, and Michael J. Thrall, MDPart III: Fine-Needle Aspiration, Superficial256 Superficial Aspiration TechniqueRose Anton, MD and Dina R. Mody, MD260 Ultrasound-Guided Thyroid Fine-Needle AspirationPaula J. Woodward, MD266 Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen AdequacyDina R. Mody, MD268 Adenomatous (Benign Follicular) NoduleMojgan Amrikachi, MD and Dina R. Mody, MD270 Chronic Lymphocytic/Hashimoto ThyroiditisMojgan Amrikachi, MD and Dina R. Mody, MD272 Granulomatous ThyroiditisMojgan Amrikachi, MD and Dina R. Mody, MD274 Graves Disease/Diffuse Toxic GoiterMukul K. Divatia, MD and Dina R. Mody, MD275 Pigmented Thyroid Lesions and CrystalsMukul K. Divatia, MD and Dina R. Mody, MD276 Atypia of Undetermined Significance/Follicular Lesion of Undetermined SignificanceDina R. Mody, MD280 Follicular Neoplasm/Suspicious for a Follicular NeoplasmDina R. Mody, MD284 Follicular Neoplasm, Oncocytic (Hürthle Cell) TypeMojgan Amrikachi, MD and Dina R. Mody, MD286 Papillary Thyroid Carcinoma, Classic SubtypeMojgan Amrikachi, MD and Dina R. Mody, MD290 Papillary Thyroid Carcinoma SubtypesMojgan Amrikachi, MD and Dina R. Mody, MD298 Medullary Thyroid CarcinomaMojgan Amrikachi, MD and Dina R. Mody, MD302 Poorly Differentiated Thyroid CarcinomaSusan L. Haley, MD and Dina R. Mody, MD304 Anaplastic Thyroid CarcinomaSusan L. Haley, MD and Dina R. Mody, MD306 Thyroid LymphomaSusan L. Haley, MD and Dina R. Mody, MD308 Metastatic Carcinoma to ThyroidSusan L. Haley, MD and Dina R. Mody, MD310 Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNAMojgan Amrikachi, MD and Dina R. Mody, MD318 Parathyroid Cyst, Adenoma, and Carcinoma Susan L. Haley, MD, Rose Anton, MD, and Dina R. Mody, MDOVERVIEW324 Lymph Node Aspiration: Indications, Techniques, and ReportingRose Anton, MD and Dina R. Mody, MD326 FNA Sample Prep and Triage in Evaluating Suspected LymphomaJohn M. Stewart, MD, PhD and Savitri Krishnamurthy, MDBENIGN, INFECTIOUS, AND REACTIVE HYPERPLASIA328 Inflammatory and Reactive Lymphoid HyperplasiaRose Anton, MD and Savitri Krishnamurthy, MD330 Granulomatous Lymphadenitis, Infectious and SarcoidRose Anton, MD and Savitri Krishnamurthy, MD334 Rosai-Dorfman DiseaseRose Anton, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MDMETASTATIC MALIGNANCIES336 Metastatic Malignancies (Carcinoma, Melanoma)Rose Anton, MD and Dina R. Mody, MD338 HPV-Positive Head and Neck Squamous Cell CarcinomaMary R. Schwartz, MD and Dina R. Mody, MDNODAL B-CELL LYMPHOMA342 Small Lymphocytic Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD344 Lymphoplasmacytic Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD346 Mantle Cell Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD348 Nodal Marginal Zone Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD350 Follicular Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD352 Burkitt Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD354 Large B-Cell Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MDEXTRANODAL B-CELL LYMPHOMA356 Plasmacytoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD358 Mediastinal Large B-Cell Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD360 Plasmablastic Lymphoma John M. Stewart, MD, PhD, Nancy P. Caraway, MD, and Savitri Krishnamurthy, MDT-CELL LYMPHOMA362 Peripheral T-Cell Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD364 Mycosis Fungoides Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD366 Angioimmunoblastic Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD368 ALK(+) Anaplastic Large Cell Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD370 T-Cell Lymphoblastic Lymphoma Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MDHODGKIN LYMPHOMA372 Nodular Lymphocyte-Predominant Hodgkin LymphomaNancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD374 Classic Hodgkin LymphomaNancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MDOVERVIEW378 Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System) Dina R. Mody, MDBENIGN LESIONS382 Normal Salivary Gland and Sialadenitis on AspirationRose Anton, MD and Dina R. Mody, MD384 CystsRose Anton, MD and Dina R. Mody, MD386 Pleomorphic AdenomaRose Anton, MD and Dina R. Mody, MD388 Warthin TumorRose Anton, MD and Dina R. Mody, MD390 MyoepitheliomaRose Anton, MD and Dina R. Mody, MD391 Oncocytoma, Salivary GlandDina R. Mody, MDMALIGNANT NEOPLASMS392 Adenoid Cystic CarcinomaRose Anton, MD and Dina R. Mody, MD394 Acinic Cell CarcinomaRose Anton, MD and Dina R. Mody, MD396 Mucoepidermoid CarcinomaRose Anton, MD and Dina R. Mody, MD398 Basaloid Neoplasms, Benign and MalignantHidehiro Takei, MD and Dina R. Mody, MD400 Carcinoma Ex Pleomorphic AdenomaHidehiro Takei, MD402 Adenocarcinoma, NOS 404 Polymorphous AdenocarcinomaHidehiro Takei, MD and Dina R. Mody, MD406 Salivary Duct CarcinomaHidehiro Takei, MD and Dina R. Mody, MD408 Secretory CarcinomaMichael J. Thrall, MD410 Myoepithelial CarcinomaShubhada Kane, MD and Michael J. Thrall, MD411 Cribriform AdenocarcinomaShubhada Kane, MD and Michael J. Thrall, MD412 Metastatic CarcinomaHidehiro Takei, MD414 Primary and Metastatic Nonepithelial TumorsDina R. Mody, MD and Hidehiro Takei, MDOVERVIEW418 Role of Fine-Needle Aspiration of Breast, Techniques and Triple TestSavitri Krishnamurthy, MDBENIGN BREAST LESIONS420 Inflammatory and Granulomatous ConditionsSavitri Krishnamurthy, MD422 Fat NecrosisSavitri Krishnamurthy, MD424 Nonproliferative and Proliferative Changes in BreastSavitri Krishnamurthy, MD428 Radial Scar/Complex Sclerosing LesionSavitri Krishnamurthy, MD430 GynecomastiaSavitri Krishnamurthy, MD432 Mucocele-Like LesionSavitri Krishnamurthy, MDBENIGN NEOPLASMS434 FibroadenomaSavitri Krishnamurthy, MD438 Granular Cell Tumor of BreastSavitri Krishnamurthy, MD440 Papillary NeoplasmsSavitri Krishnamurthy, MD446 Myofibroblastoma, MammarySavitri Krishnamurthy, MDMALIGNANT NEOPLASMS448 Ductal Carcinoma and Variants of Invasive Mammary CarcinomaSavitri Krishnamurthy, MD456 Lobular CarcinomaSavitri Krishnamurthy, MD458 Phyllodes TumorSavitri Krishnamurthy, MD460 Angiosarcoma and Other SarcomasSavitri Krishnamurthy, MD464 Lymphomas and Metastatic TumorsSavitri Krishnamurthy, MDNIPPLE DISCHARGE466 Cytology Specimens for Risk Assessment of Breast CancerSavitri Krishnamurthy, MD470 Cutaneous and Adnexal CytologyMary R. Schwartz, MD and Dina R. Mody, MDPart IV: Fine-Needle Aspiration, Deep Organs and Tissues476 Techniques and Modalities of Deep Aspiration BiopsiesPaula J. Woodward, MD and Ashraf Thabet, MDOVERVIEW482 Anatomic Compartments and Constituent TumorsMing Guo, MD and Savitri Krishnamurthy, MDNONNEOPLASTIC LESIONS484 Mediastinal Cysts and Inflammatory LesionsMing Guo, MD and Savitri Krishnamurthy, MDNEOPLASMS486 ThymomaMing Guo, MD and Savitri Krishnamurthy, MD488 Thymic CarcinomaMing Guo, MD and Savitri Krishnamurthy, MD490 Germ Cell TumorsMing Guo, MD and Savitri Krishnamurthy, MD492 Neurogenic TumorsMing Guo, MD and Savitri Krishnamurthy, MD494 Metastatic Tumors of MediastinumMing Guo, MD and Savitri Krishnamurthy, MDOVERVIEW498 Cytology of Normal Liver Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MD500 Inflammatory and Infectious Conditions of Liver Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MDBENIGN HEPATIC NEOPLASMS502 Hepatocellular Adenoma Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MD504 Focal Nodular Hyperplasia Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MD506 Hemangioma, Liver Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MDMALIGNANT NEOPLASMS508 Hepatocellular Carcinoma Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MD510 Hepatoblastoma Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MD512 Liver Metastasis Elizabeth M. Jacobi, MD, Rose Anton, MD, and Michael J. Thrall, MDOVERVIEW516 Cytology of Normal KidneyYimin Ge, MDBENIGN LESIONS AND NEOPLASMS518 Renal CystsYimin Ge, MD520 AngiomyolipomaYimin Ge, MD522 Oncocytoma, KidneyYimin Ge, MD524 Metanephric AdenomaYimin Ge, MD and Jun Zhang, MD, MS526 Metanephric Stromal TumorYimin Ge, MD and Norma Quintanilla, MD527 Xanthogranulomatous Pyelonephritis/MalakoplakiaYimin Ge, MDMALIGNANT NEOPLASMS528 Clear Cell Renal Cell CarcinomaYimin Ge, MD532 Papillary Renal Cell CarcinomaYimin Ge, MD534 Clear Cell Papillary Renal Cell CarcinomaMichael J. Thrall, MD536 Chromophobe Renal Cell CarcinomaYimin Ge, MD538 TFE3- andTFEB-Rearranged Renal Cell CarcinomasMichael J. Thrall, MD540 Collecting Duct CarcinomaYimin Ge, MD and Jun Zhang, MD, MS541 Renal Medullary CarcinomaYimin Ge, MD542 Mucinous Tubular and Spindle Cell Carcinoma of KidneyYimin Ge, MD543 Carcinoid TumorYimin Ge, MD544 Primary Renal Sarcomas in AdultsYimin Ge, MD and Jun Zhang, MD, MS545 Renal LymphomasYimin Ge, MD and Jun Zhang, MD, MS546 Nephroblastoma (Wilms Tumor) Yimin Ge, MD, Jun Zhang, MD, MS, and Norma Quintanilla, MD548 Clear Cell Sarcoma of KidneyYimin Ge, MD and Norma Quintanilla, MD550 Congenital Mesoblastic NephromaYimin Ge, MD and Norma Quintanilla, MD552 Rhabdoid Tumor of KidneyYimin Ge, MD and Norma Quintanilla, MD553 Metastatic Tumors to KidneyYimin Ge, MDTUMORS OF RENAL PELVIS554 Urothelial CarcinomaYimin Ge, MDOVERVIEW558 Cytology of Normal Adrenal GlandYimin Ge, MDADRENAL CORTICAL LESIONS560 Adrenal Cortical AdenomaYimin Ge, MD562 Adrenal Cortical CarcinomaYimin Ge, MD564 Metastatic Tumors to Adrenal GlandYimin Ge, MDADRENAL MEDULLARY LESIONS566 PheochromocytomaYimin Ge, MDOVERVIEW570 Cytology of Normal PancreasUma Kundu, MD and Dina R. Mody, MD572 Pancreaticobiliary Cytology Reporting Terminology, Cyst EvaluationDina R. Mody, MD and Mary R. Schwartz, MDNONNEOPLASTIC LESIONS574 PancreatitisUma Kundu, MD and Dina R. Mody, MD576 Lymphoepithelial Cyst of PancreasDina R. Mody, MD577 Intra- and Peripancreatic SplenulesDina R. Mody, MD578 Serous Microcystic AdenomaUma Kundu, MD and Savitri Krishnamurthy, MDMucinous Cystic NeoplasmUma Kundu, MD and Savitri Krishnamurthy, MD582 Intraductal Papillary Mucinous NeoplasmUma Kundu, MD and Savitri Krishnamurthy, MD584 Solid Pseudopapillary NeoplasmGene Landon, MD and Savitri Krishnamurthy, MD586 Pancreatic Neuroendocrine TumorGene Landon, MD and Savitri Krishnamurthy, MD588 Pancreatic Ductal AdenocarcinomaGene Landon, MD and Savitri Krishnamurthy, MDUnusual Variants of Ductal CarcinomaSavitri Krishnamurthy, MD594 Acinar Cell CarcinomaSavitri Krishnamurthy, MD596 Lymphoma and Secondary Tumors of PancreasSavitri Krishnamurthy, MDOVERVIEWApproach to Cytologic/Small Biopsy Diagnosis of Primary Bone TumorsDina R. Mody, MDNEOPLASMS602 Chondromas of Bone and Soft TissueMukul K. Divatia, MD and Dina R. Mody, MD604 ChondroblastomaDina R. Mody, MD606 Giant Cell TumorDina R. Mody, MD608 OsteoblastomaDina R. Mody, MDAdamantinomaDina R. Mody, MD612 Langerhans Cell HistiocytosisDina R. Mody, MD614 ChordomaDina R. Mody, MD616 OsteosarcomaSavitri Krishnamurthy, MDChondrosarcomaSavitri Krishnamurthy, MD624 Ewing SarcomaSavitri Krishnamurthy, MD628 Bone LymphomaDina R. Mody, MDMetastatic Tumors of BoneDina R. Mody, MDOVERVIEW634 Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue LesionsDina R. Mody, MDADIPOCYTIC TUMORS636 Benign Adipose Tissue TumorsUma Kundu, MD and Savitri Krishnamurthy, MD638 LiposarcomaUma Kundu, MD and Savitri Krishnamurthy, MDFIBROBLASTIC/MYOFIBROBLASTIC LESIONS642 FibrosarcomaUma Kundu, MD and Savitri Krishnamurthy, MD644 MyofibroblastomaSavitri Krishnamurthy, MD646 Low-Grade Myofibroblastic SarcomaUma Kundu, MD and Savitri Krishnamurthy, MDFIBROHISTIOCYTIC TUMORS648 Giant Cell Tumor of Tendon SheathUma Kundu, MD and Savitri Krishnamurthy, MD650 Undifferentiated Pleomorphic SarcomaUma Kundu, MD and Savitri Krishnamurthy, MDTUMORS OF MUSCLE ORIGIN652 Smooth Muscle TumorsGene Landon, MD and Savitri Krishnamurthy, MD654 Skeletal Muscle TumorsGene Landon, MD and Savitri Krishnamurthy, MDVASCULAR TUMORS658 Hemangioma, Soft TissueGene Landon, MD and Michael J. Thrall, MD660 Epithelioid HemangioendotheliomaGene Landon, MD and Michael J. Thrall, MD662 AngiosarcomaGene Landon, MD and Savitri Krishnamurthy, MDOTHER TUMORS664 Other Reactive and Neoplastic Soft Tissue EntitiesDina R. Mody, MD666 Mesenchymal ChondrosarcomaDina R. Mody, MD667 Solitary Fibrous TumorDina R. Mody, MD668 Intramuscular MyxomaGene Landon, MD and Savitri Krishnamurthy, MD670 Synovial SarcomaGene Landon, MD and Savitri Krishnamurthy, MD672 Epithelioid SarcomaGene Landon, MD and Savitri Krishnamurthy, MD674 Alveolar Soft Part SarcomaUma Kundu, MD and Savitri Krishnamurthy, MD676 Clear Cell Sarcoma of Soft TissueUma Kundu, MD and Savitri Krishnamurthy, MD678 Desmoplastic Small Round Cell TumorUma Kundu, MD and Savitri Krishnamurthy, MD682 Approach to Ophthalmic CytologyPatricia Chévez-Barrios, MD686 Ophthalmic Cytopathology, InfectiousPatricia Chévez-Barrios, MD690 Ophthalmic Cytopathology, NeoplasticPatricia Chévez-Barrios, MD696 Neuropathology Squash Preparations, InfectiousAndreana L. Rivera, MD, Suzanne Z. Powell, MD, and Hidehiro Takei, MD700 Neuropathology Squash Preparations, Glial NeoplasmsSuzanne Z. Powell, MD, Andreana L. Rivera, MD, and Hidehiro Takei, MD704 Neuropathology Squash Preparations, Nonglial NeoplasmsAndreana L. Rivera, MD, Suzanne Z. Powell, MD, and Hidehiro Takei, MDPart V: Management and Ancillary Testing710 Cytopreparatory Techniques and Instrumentation in Nongynecologic CytologyDebora A. Smith, CT(ASCP) and Dina R. Mody, MD716 Quality Improvement and Laboratory Management for CytopathologyDebora A. Smith, CT(ASCP) and Dina R. Mody, MDSavitri Krishnamurthy, MD