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Montserrat Diéguez - Chiral Ligands, Häftad

Häftad, Engelska, 2024

Chiral Ligands

Evolution of Ligand Libraries for Asymmetric Catalysis

Av Montserrat Diéguez

Del i serien New Directions in Organic & Biological Chemistry

993 kr

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Beskrivning
Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.Key Features:The book presents historical content from the time of discovery for each family of ligands.Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactionsSuitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable productionEdited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations
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Montserrat Diéguez studied chemistry at the Rovira i Virgili University (URV)in Tarragona (Spain), where she earned her Ph.D. in 1997, working in the groupof Prof. C. Claver. After completing a postdoctoral fellowship where she workedwith Prof. R.H. Crabtree at Yale University, in New Haven (USA), she returned toTarragona in 1999 and accepted a lectureship position at the URV, becoming part ofthe permanent staff in 2002. In 2011 she was promoted to full Professor in InorganicChemistry at the URV.She has been involved in more than 60 research projects in the fields of organometallicchemistry, steroselective synthesis, and asymmetric catalysis. She is theauthor/co-author of more than 150 articles in SCI-indexed journals and book chapters,and of several contributions to conferences. She received distinction from theGeneralitat de Catalunya for the promotion of University Research in 2004 and fromthe URV in 2008. She has also been awarded the ICREA Academia Prize fromthe Catalan Institution for Research and Advanced Studies 2009–14 and 2015–20,for research excellence, facilitating research priority dedication. Her main researchinterests are focused on the sustainable design, synthesis, and screening of highlyactive and selective chiral catalysts for reactions of interest to the biological, pharmaceutical,and organic nanotechnological industries. Her areas of interest includeorganometallic chemistry, stereoselective synthesis, and asymmetric catalysis, usingcombinatorial and biotechnological approaches.

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