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    Chiral Ligands

    Evolution of Ligand Libraries for Asymmetric Catalysis

    AvMontserrat Diéguez

    Häftad, Engelska, 2024

    Del i serien New Directions in Organic & Biological Chemistry

    962 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.Key Features:The book presents historical content from the time of discovery for each family of ligands.Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactionsSuitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable productionEdited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations

    Produktinformation

    • Utgivningsdatum:2024-05-27
    • Mått:156 x 234 x 21 mm
    • Vikt:453 g
    • Format:Häftad
    • Språk:Engelska
    • Serie:New Directions in Organic & Biological Chemistry
    • Antal sidor:322
    • Förlag:Taylor & Francis Ltd
    • ISBN:9780367761707

    Utforska kategorier

    • Biokemi inom Naturvetenskap och teknik
    • Farmakologi inom Medicin
    • Kemi inom Naturvetenskap och teknik

    Mer om författaren

    Montserrat Diéguez studied chemistry at the Rovira i Virgili University (URV)in Tarragona (Spain), where she earned her Ph.D. in 1997, working in the groupof Prof. C. Claver. After completing a postdoctoral fellowship where she workedwith Prof. R.H. Crabtree at Yale University, in New Haven (USA), she returned toTarragona in 1999 and accepted a lectureship position at the URV, becoming part ofthe permanent staff in 2002. In 2011 she was promoted to full Professor in InorganicChemistry at the URV.She has been involved in more than 60 research projects in the fields of organometallicchemistry, steroselective synthesis, and asymmetric catalysis. She is theauthor/co-author of more than 150 articles in SCI-indexed journals and book chapters,and of several contributions to conferences. She received distinction from theGeneralitat de Catalunya for the promotion of University Research in 2004 and fromthe URV in 2008. She has also been awarded the ICREA Academia Prize fromthe Catalan Institution for Research and Advanced Studies 2009–14 and 2015–20,for research excellence, facilitating research priority dedication. Her main researchinterests are focused on the sustainable design, synthesis, and screening of highlyactive and selective chiral catalysts for reactions of interest to the biological, pharmaceutical,and organic nanotechnological industries. Her areas of interest includeorganometallic chemistry, stereoselective synthesis, and asymmetric catalysis, usingcombinatorial and biotechnological approaches.

    Innehållsförteckning

    • ContentsPreface......................................................................................................................viiEditor.........................................................................................................................ixList of Contributors....................................................................................................xiAbbreviations and Acronyms................................................................................. xiiiChapter 1 Chiral Bidentate Heterodonor P-Oxazoline Ligands ...........................1Maria Biosca, Jordi Faiges, Montserrat Diéguez,and Oscar PàmiesChapter 2 Chiral Bidentate Heterodonor P-N-Other-Ligands............................. 33Pep Rojo, Marina Bellido, Xavier Verdaguer, and Antoni RieraChapter 3 Chiral Bidentate Heterodonor P,S/O Ligands..................................... 81Jèssica Margalef and Miquel A. PericàsChapter 4 Chiral Bidentate Heterodonor P-P’ ligands....................................... 109Antonio PizzanoChapter 5 Chiral Tridentate-Based Ligands...................................................... 167Uchchhal Bandyopadhyay, Basker Sundararaju, Rinaldo Poli,and Eric ManouryChapter 6 Chiral N-Heterocyclic Carbene-Based Ligands................................ 195Vincent César, Christophe Fliedel, and Agnès LabandeChapter 7 Chiral Monophosphorus Ligands...................................................... 233Wenjun Tang, Feng Wan, and He YangChapter 8 Solvent-Oriented Ligand and Catalyst Design in AsymmetricCatalysis – Principles and Limits ..................................................... 261Armin BörnerIndex....................................................................................................................... 315