Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

AvPatrick Augustijns,Marcus Brewster

Inbunden, Engelska, 2007

Del i serien Biotechnology: Pharmaceutical Aspects

2 328 kr

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Beskrivning

Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Produktinformation

Utgivningsdatum:2007-06-08
Mått:178 x 254 x 34 mm
Vikt:1 080 g
Format:Inbunden
Språk:Engelska
Serie:Biotechnology: Pharmaceutical Aspects
Antal sidor:462
Förlag:Springer-Verlag New York Inc.
ISBN:9780387691497

Utforska kategorier

Tillverkningsteknik inom Naturvetenskap och teknik

Innehållsförteckning

Principles of Solubility.- Ionic Equilibria and the pH Dependence of Solubility.- Solvent Systems for Crystallization and Polymorph Selection.- Solubility Issues in Early Discovery and HTS.- Practical Aspects of Solubility Determination in Pharmaceutical Preformulation.- Biorelevant Dissolution Media.- Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Assessment.- The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines.- Solubilizing Vehicles for Oral Formulation Development.- Solubilizing Systems for Parenteral Formulation Development—Small Molecules.- Aqueous Solubilizing Systems for Parenteral Formulation Development—Proteins.- Non-Aqueous Systems for Formulation Development—Proteins.- Pharmaceutical Solvents as Vehicles for Topical Dosage Forms.- Pharmaceutical Solvents for Pulmonary Drug Delivery.

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