The modification of cells and organisms by the insertion of new genes is one of the most powerful tools of modern biology. These rapidly developing techniques have enabled researchers to dissect and manipulate biological processes of fundamental and economic importance. This volume results from the Royal Society discussion meeting on transgenic modification of plants and animals held in 1992. Overview chapters assess the current understanding of genetic modification and their applications in both plants and animals. Topics reviewed include: progress in genome mapping; sex determination and embryo formation; epigenetic variation; gene switches and control of development; stem cell manipulation; genetic enhancement of organisms by gene insertion; and disease investigation. Throughout, examples are drawn from the latest research on both plants and animals. Key references provide a guide to the literature. This book should be of interest to researchers and post-graduate students using or considering using, transgenic technology.
