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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Biologi
    4. Biovetenskap

    Medical and Health Genomics of South Asia

    AvDhavendra Kumar,Kumarasamy Thangaraj

    Häftad, Engelska, 2027

    Del i serien Genomic and Precision Medicine in Clinical Practice

    2 147 kr

    Beställningsvara. Skickas inom 11-20 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

    • Provides a detailed examination of medical genomics as applied in South Asian populations, including current and origin populations
    • Considers genetic and genomic epidemiological approaches for studying and treating genetic, infectious, and lifestyle diseases across South Asia, with an emphasis on heterogeneity
    • Highlights population health challenges with global prevalence
    • Acts as a practical reference for genomic education and implementation in the region
    • Features contributing experts from various South Asian nations and beyond

    Produktinformation

    • Utgivningsdatum:2027-07-02
    • Mått:191 x 235 x undefined mm
    • Format:Häftad
    • Språk:Engelska
    • Serie:Genomic and Precision Medicine in Clinical Practice
    • Antal sidor:804
    • Förlag:Elsevier Science
    • ISBN:9780443159220

    Utforska kategorier

    • Biovetenskap inom Naturvetenskap och teknik

    Mer om författaren

    Professor Dhavendra Kumar is a Visiting Professor within the Genomic Policy Unit, Faculty of Life Sciences and Education, at the University of South Wales; and a Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with a MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK). Dr. Kumarasamy Thangaraj is JC Bose Fellow CSIR-,CCMB Hyderabad, India. His major research interest sits in the fields of human origins, health and disease. He is interested in understanding the complex origin and affinities of Indian populations, using the genomics variations of contemporary populations and ancient biological remains. He is also interested in understanding the impact of endogamy on health and disease of South Asians. Dr. has published widely in such peer reviewed journals as Nature, the American Journal of Human Genetics, Molecular Biology and Evolution, and Current Biology.

    Innehållsförteckning

    • Section I: Basic human genetics and genomics1. Population origin and variation of the South Asian peoples2. Introduction to genomic and molecular biology3. Microbial and Pathogenomics with reference to tropical infections4. Pharmacogenetics and Pharmacogenomics including traditional/ indigenous herbal medicines5. South Asia genomic heterogeneity in transplantation medicineSection II: Hereditary disorders of the South Asian subcontinent6. Spectrum and Epidemiology of inherited disorders of Indian subcontinent7. Heterogeneity of hereditary diseases in South Asia8. Metabolic and mitochondrial diseases9. Haemoglobinopathies and related inherited blood diseases10. Inherited cardiovascular diseases11. Genetic immunology- Primary immune deficiency disorders12. Familial and Inherited cancer13. Rare genetic diseases in IndiaSection III: Genomics of Infectious diseases14. Malaria genomics and applications15. Mycobacterial diseases genomics and Tuberculosis Including Leprosy16. Leishmaniasis- the paradigm of tropical infectious disease17. Anti-microbial therapy- resistance; response; adverse drug reactions18. Next generation drugs and vaccines in South AsiaSection IV: Environmental and Life style diseases (Non-Communicable diseases)19. Diabetes and related glycemic diseases20. Coronary artery disease and Hypertension in South Asia- genetic perspectives21. Respiratory diseases- Bronchial asthma and High altitude living22. Inflammatory/ Auto-immune diseasesSection V: Health genomics of the South Asia23. Health perspectives of ancient Indian and South Asian DNA24. The organisation and function of clinical genomics & genetic counselling25. Genome laboratories and Genome database systems26. Fertility and Assisted Reproduction27. Fetal Medicine and Newborn screening28. Genetic and genomic education & training in South Asia29. Human genomics in Sri Lanka- from clinics to community30. Clinical and Molecular genetic initiatives in Nepal31. Human Genomic Disease-Specific Database Development: The Model of the Global Globin Database32. Medical genetics and genetic counselling in Bangladesh33. Genomic variation- Regional and socio-cultural perspectives34. Ethical, Legal and Social Issues (ELSI)- South Asian perspectivesGlossary- Human and Medical Genetics & Genomics; Population/Public Health