Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy

Dr. Akhileshwar Kumar Srivastava works as a Research Associate (ICMR) at CSIR-Central Food Technological Research Institute, Mysore, India. In his 11 years of research, he has published more than 18 research articles in reputed international journals, along with 4 books and 11 book chapters. His research specialization is primarily in the area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology associated with targeting virulent factors of diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, USA, on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel. He is also a life member fellow in the Indian Science Congress and the Agriculture, Nutrition and Health Academy, UK. Divya Singh is presently working as Scientist-B in Department of Mulberry Physiology, CSRTI, Mysore, India. Her research specialization is primarily in genetics, proteomics, metabolomics, toxicology, bioinformatics and molecular biological evaluation in various in vivo and in vitro plant models to elucidate the physiological changes and evaluate the DNA damage potency. In her 11 years of research experiences, she has published 8-peer reviewed publications, two books (1 edited and 1 authored) including 6 book chapters and several meeting presentations at local and international scientific meetings. Dr. Rajesh Kumar Singh is currently working as a Research Associate in Banaras Hindu University. His research focus is pharmacognosy, reverse pharmacology, drug design and discovery, extraction & isolation of natural products, cell culture, and handling of different rodents. He has published several research articles in reputable journals over the course of his career. At present, he is involved in developing an Indian origin cell line and screening drugs of natural origin for the treatment of gallbladder cancer.

• 1. Significance of phytochemicals in cancer therapy2. Emerging need of delivery systems for plant metabolites3. Phytosome: A promising drug-delivery system for cancer therapy4. Exosome-based delivery systems for natural compounds in cancer therapy5. Potential implications of ethosomes and transethosomes to deliver phytomedicine in cancer treatment6. Chitosan-based drug delivery of plant metabolites for the treatment of breast cancer7. Sporopollenin-based targeted drug delivery system for gastrointestinal cancer8. Nanotechnology based delivery system for phytochemicals in cancer therapy9. Delivery system of phenolic compounds for the treatment of lung cancer10. Advancement in drug delivery systems of curcumin for cancer chemoprevention11. Drug delivery system for saponins in cancer treatments12. Administration of plant-derived terpenoids in cancer management13. Therapeutic role of essential oils in malignancies through drug delivery mechanisms14. Development of codelivery system for phytochemicals and targeted siRNA in cancer therapy15. Future challenges of drug-delivery systems for phytochemicals in cancer management