Gautam Patel obtained PG from Institute of Science and Technology for Advanced Studies and Research (ISTAR), Vallabh Vidya Nagar and Doctoral degree from the M. S. University of Baroda, India. He is the Head and an Associate Professor at the Chemistry Department, Parul Institute of Applied Science, Parul University, India. His area of specialization is organic synthesis, green chemistry, nanosciences and nanotechnology. He has 3 patents to his name.Vraj R. Shah has received his B.Sc. in Industrial Chemistry from ITM Vocational University and M.Sc. degrees in Industrial Chemistry from ITM (SLS) Baroda University, Vadodara. Following his graduation, he is currently working as a graduate research assistant at the department of Chemical and Biological Engineering at The University of Alabama, USA. He has published 5 research papers in the peer-review international journals. He has contributed 8 book chapters with peer reviewed books of international publishers. His research interest mainly focuses on organic synthesis, medicinal chemistry, computational simulations, membrane synthesis, and nanotechnology. In addition, he has also received the prestigious GCF fellowship from University of Alabama to pursue his doctoral degree. Moreover, he has also been awarded “Best young researcher presentation ” from Sardar Vallabhbhai Patel National Institute of Technology (SVNIT).Tuan Anh Nguyen is a Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. He received a BS in physics from Hanoi University in 1992, a BS in economics from Hanoi National Economics University in 1997, and a PhD in chemistry from the Paris Diderot University, France, in 2003. He was a Visiting Scientist at Seoul National University, South Korea, in 2004, and the University of Wollongong, Australia, in 2005. He then worked as a Postdoctoral Research Associate and Research Scientist at Montana State University, United States in 2006-09. In 2012 he was appointed as the Head of the Microanalysis Department at the Institute for Tropical Technology. His research areas of interest include smart sensors, smart networks, smart hospitals, smart cities, complexiverse, and digital twins. He has edited more than 74 books for Elsevier, 12 books for CRC Press, 1 book for Springer, 1 book for RSC, and 2 books for IGI Global. He is the Editor-in-Chief of Kenkyu Journal of Nanotechnology & Nanoscience. Dr. Kalim Deshmukh is a senior researcher at the New Technologies Research Centre, University of West Bohemia in Pilsen, Czech Republic. He has over 20 years of research experience in nanomaterials and polymeric materials, with particular expertise in polymer blends, nanocomposites, and nanohybrids. His work emphasizes nanoscale dispersion, interfacial chemistry, and structure–property relationships that influence material performance in applications such as energy storage, gas sensing, biosensing, electromagnetic interference (EMI) shielding, and high-k dielectrics. He has authored more than 200 publications, including original research articles and review papers, in leading international journals and with major publishers, such as the Royal Society of Chemistry (RSC), American Chemical Society (ACS), Elsevier, Wiley-VCH, Springer, and Taylor & Francis. In addition to his research contributions, he has edited or co-edited several books published by ACS, RSC, Elsevier, Springer, Wiley-VCH, and Wiley Scrivener.

• 1. Introduction of Spirooxindole2. Synthesis of spirooxindole and its derivatives using green and nano technology3. Stereoselective synthesis of spirooxindole scaffold4. Characterization techniques for synthesised spirooxindole scaffold5. Spirooxindole as a precursor6. Medicinal applications of Spirooxindole and its derivatives- An Introduction7. Spirooxindole derivatives as an anti-cancer agent8. Spirooxindole derivatives as kinase based anti-cancer agents9. Spirooxindole derivatives as an anti-viral agent10. Spirooxindole derivatives as an anti-bacterial agent11. Spirooxindole derivatives as an anti-oxidant agent12. Spirooxindole derivatives as an anti-inflammatory agent13. Other Medicinal Applications14. A case study of the use of spirooxindole derivatives in the novel drug discovery

Gautam Patel obtained PG from Institute of Science and Technology for Advanced Studies and Research (ISTAR), Vallabh Vidya Nagar and Doctoral degree from the M. S. University of Baroda, India. He is the Head and an Associate Professor at the Chemistry Department, Parul Institute of Applied Science, Parul University, India. His area of specialization is organic synthesis, green chemistry, nanosciences and nanotechnology. He has 3 patents to his name.Vraj R. Shah has received his B.Sc. in Industrial Chemistry from ITM Vocational University and M.Sc. degrees in Industrial Chemistry from ITM (SLS) Baroda University, Vadodara. Following his graduation, he is currently working as a graduate research assistant at the department of Chemical and Biological Engineering at The University of Alabama, USA. He has published 5 research papers in the peer-review international journals. He has contributed 8 book chapters with peer reviewed books of international publishers. His research interest mainly focuses on organic synthesis, medicinal chemistry, computational simulations, membrane synthesis, and nanotechnology. In addition, he has also received the prestigious GCF fellowship from University of Alabama to pursue his doctoral degree. Moreover, he has also been awarded “Best young researcher presentation ” from Sardar Vallabhbhai Patel National Institute of Technology (SVNIT).Tuan Anh Nguyen is a Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. He received a BS in physics from Hanoi University in 1992, a BS in economics from Hanoi National Economics University in 1997, and a PhD in chemistry from the Paris Diderot University, France, in 2003. He was a Visiting Scientist at Seoul National University, South Korea, in 2004, and the University of Wollongong, Australia, in 2005. He then worked as a Postdoctoral Research Associate and Research Scientist at Montana State University, United States in 2006-09. In 2012 he was appointed as the Head of the Microanalysis Department at the Institute for Tropical Technology. His research areas of interest include smart sensors, smart networks, smart hospitals, smart cities, complexiverse, and digital twins. He has edited more than 74 books for Elsevier, 12 books for CRC Press, 1 book for Springer, 1 book for RSC, and 2 books for IGI Global. He is the Editor-in-Chief of Kenkyu Journal of Nanotechnology & Nanoscience. Dr. Kalim Deshmukh is a senior researcher at the New Technologies Research Centre, University of West Bohemia in Pilsen, Czech Republic. He has over 20 years of research experience in nanomaterials and polymeric materials, with particular expertise in polymer blends, nanocomposites, and nanohybrids. His work emphasizes nanoscale dispersion, interfacial chemistry, and structure–property relationships that influence material performance in applications such as energy storage, gas sensing, biosensing, electromagnetic interference (EMI) shielding, and high-k dielectrics. He has authored more than 200 publications, including original research articles and review papers, in leading international journals and with major publishers, such as the Royal Society of Chemistry (RSC), American Chemical Society (ACS), Elsevier, Wiley-VCH, Springer, and Taylor & Francis. In addition to his research contributions, he has edited or co-edited several books published by ACS, RSC, Elsevier, Springer, Wiley-VCH, and Wiley Scrivener.

• 1. Introduction of Spirooxindole2. Synthesis of spirooxindole and its derivatives using green and nano technology3. Stereoselective synthesis of spirooxindole scaffold4. Characterization techniques for synthesised spirooxindole scaffold5. Spirooxindole as a precursor6. Medicinal applications of Spirooxindole and its derivatives- An Introduction7. Spirooxindole derivatives as an anti-cancer agent8. Spirooxindole derivatives as kinase based anti-cancer agents9. Spirooxindole derivatives as an anti-viral agent10. Spirooxindole derivatives as an anti-bacterial agent11. Spirooxindole derivatives as an anti-oxidant agent12. Spirooxindole derivatives as an anti-inflammatory agent13. Other Medicinal Applications14. A case study of the use of spirooxindole derivatives in the novel drug discovery

Gautam Patel obtained PG from Institute of Science and Technology for Advanced Studies and Research (ISTAR), Vallabh Vidya Nagar and Doctoral degree from the M. S. University of Baroda, India. He is the Head and an Associate Professor at the Chemistry Department, Parul Institute of Applied Science, Parul University, India. His area of specialization is organic synthesis, green chemistry, nanosciences and nanotechnology. He has 3 patents to his name.Vraj R. Shah has received his B.Sc. in Industrial Chemistry from ITM Vocational University and M.Sc. degrees in Industrial Chemistry from ITM (SLS) Baroda University, Vadodara. Following his graduation, he is currently working as a graduate research assistant at the department of Chemical and Biological Engineering at The University of Alabama, USA. He has published 5 research papers in the peer-review international journals. He has contributed 8 book chapters with peer reviewed books of international publishers. His research interest mainly focuses on organic synthesis, medicinal chemistry, computational simulations, membrane synthesis, and nanotechnology. In addition, he has also received the prestigious GCF fellowship from University of Alabama to pursue his doctoral degree. Moreover, he has also been awarded “Best young researcher presentation ” from Sardar Vallabhbhai Patel National Institute of Technology (SVNIT).Tuan Anh Nguyen is a Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. He received a BS in physics from Hanoi University in 1992, a BS in economics from Hanoi National Economics University in 1997, and a PhD in chemistry from the Paris Diderot University, France, in 2003. He was a Visiting Scientist at Seoul National University, South Korea, in 2004, and the University of Wollongong, Australia, in 2005. He then worked as a Postdoctoral Research Associate and Research Scientist at Montana State University, United States in 2006-09. In 2012 he was appointed as the Head of the Microanalysis Department at the Institute for Tropical Technology. His research areas of interest include smart sensors, smart networks, smart hospitals, smart cities, complexiverse, and digital twins. He has edited more than 74 books for Elsevier, 12 books for CRC Press, 1 book for Springer, 1 book for RSC, and 2 books for IGI Global. He is the Editor-in-Chief of Kenkyu Journal of Nanotechnology & Nanoscience. Dr. Kalim Deshmukh is a senior researcher at the New Technologies Research Centre, University of West Bohemia in Pilsen, Czech Republic. He has over 20 years of research experience in nanomaterials and polymeric materials, with particular expertise in polymer blends, nanocomposites, and nanohybrids. His work emphasizes nanoscale dispersion, interfacial chemistry, and structure–property relationships that influence material performance in applications such as energy storage, gas sensing, biosensing, electromagnetic interference (EMI) shielding, and high-k dielectrics. He has authored more than 200 publications, including original research articles and review papers, in leading international journals and with major publishers, such as the Royal Society of Chemistry (RSC), American Chemical Society (ACS), Elsevier, Wiley-VCH, Springer, and Taylor & Francis. In addition to his research contributions, he has edited or co-edited several books published by ACS, RSC, Elsevier, Springer, Wiley-VCH, and Wiley Scrivener.

• 1. Introduction of Spirooxindole2. Synthesis of spirooxindole and its derivatives using green and nano technology3. Stereoselective synthesis of spirooxindole scaffold4. Characterization techniques for synthesised spirooxindole scaffold5. Spirooxindole as a precursor6. Medicinal applications of Spirooxindole and its derivatives- An Introduction7. Spirooxindole derivatives as an anti-cancer agent8. Spirooxindole derivatives as kinase based anti-cancer agents9. Spirooxindole derivatives as an anti-viral agent10. Spirooxindole derivatives as an anti-bacterial agent11. Spirooxindole derivatives as an anti-oxidant agent12. Spirooxindole derivatives as an anti-inflammatory agent13. Other Medicinal Applications14. A case study of the use of spirooxindole derivatives in the novel drug discovery