Fluorine Metabolism, Transport and Enzymatic Chemistry

Inbunden, Engelska, 2024

2 190 kr

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Beskrivning

Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more.

Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-encoded proteins in HEK cells.

Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in Methods in Enzymology series
Updated release includes the latest information on Fluorine Metabolism, Transport, and Enzymatic Chemistry

Produktinformation

Utgivningsdatum:2024-04-19
Mått:152 x 229 x 23 mm
Vikt:720 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Enzymology
Antal sidor:376
Förlag:Elsevier Science
Medarbetare:Randy Stockbridge
ISBN:9780443236433

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Mer om författaren

Randy B. Stockbridge is an Associate Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan. She also holds an appointment in the Program in Biophysics. She received her Ph.D. in Biochemistry and Biophysics in 2010 from the University of North Carolina, Chapel Hill, where she conducted mechanistic enzymology research in the laboratory of Dr. Richard Wolfenden. She carried out her postdoctoral studies in the lab of Dr. Christopher Miller at Brandeis University, where she first discovered and characterized new families of microbial fluoride export proteins. Her research lab at the University of Michigan applies structural biology, biochemistry, and biophysical approaches to understand microbial membrane physiologies, including fluoride resistance, antiseptic resistance, and metabolite transport. She serves on the Board of Reviewing Editors for the journal eLife and the editorial board for the Journal of General Physiology. She is also active in undergraduate education at the University of Michigan. She teaches Introductory Biochemistry to approximately 450 students each year, along with specialty courses on macromolecular structure. She has been awarded the Paul F. Cranefield Award from the Society of General Physiologists, and the Margaret Oakley Dayhoff Award from the Biophysical Society, an NSF CAREER award, and research awards from the Burroughs Wellcome Fund and Alfred P. Sloan Foundation.

Innehållsförteckning

1. Determination of fluoride sensitivity and resistance in oral biofilm models2. NMR methods to detect fluoride binding and transport by membrane proteins3. Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans4. Measurement of fluoride efflux from lipid vesicles and cells5. Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation6. Computational approaches to investigate F- binding, selectivity and transport in F- exporters7. Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities8. Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae9. Synthesis of fluorophenylalanine-encoded proteins in HEK cells