The Dual Role of Inflammation in Cancer

Prof. Surajit Pathak, PhD, is a professor at Chettinad Academy of Research and Education (CARE), Chennai, India since 2015. He was previously a principal research scientist (2022 June–Dec 2022) at Linkoping University, Linkoping, Sweden. He received his PhD degree from India in 2007 and completed his postdoctoral training (2007–15) from the University of Alabama, United States, the University of Padova, Italy, and the University of Linkoping, Sweden. His current research focuses on “Biomarker discoveries for early detection of colorectal cancer.” He has published more than 100 research articles in peer-reviewed international journals of repute with 2233 citations and 27 H-index. Dr. Pathak has edited Elsevier book “Stem Cells and Aging” in 2021. He is the member of various professional research bodies of India, including the Indian Association of Cancer Research and the Indian Science Congress. Dr. Antara Banerjee, PhD, is presently working as an associate professor at CARE, Chennai from 2016 to date. After completing her PhD in 2008 from India, Dr. Banerjee pursued her postdoctoral work at the University of Padova, Italy and Linkoping University, Sweden (2009–15). She has published over 95 peer-reviewed research articles in international and national journals with citation index-1408 and H-index 19. The Banerjee’s lab at Chettinad Hospital and Research Institute is now focused on understanding the role of mesenchymal stem cells niche in tissue regeneration and exploring signaling pathways in governing stem cell fate. She is the editor of Elsevier book “Stem Cells and Aging” in 2021. She is the member of various professional research bodies, including the Indian Association of Cancer Research and the Indian Science Congress.

• 1. Introduction to Inflammation and Cancer2. Chronic Inflammation and Cancer: Epidemiological Evidence3. The Role of Oxidative Stress in Inflammation-Mediated Cancer Progression4. Inflammation and Tumor Progression: Signaling Cross-Talk and Therapeutic Resistance5. Pro-and anti-tumorigenic inflammatory signalling in pancreatic cancer: Mechanistic insights and therapeutic implications6. Inflammation and Beyond: Complex Roles for TGF-β in the Tumor Microenvironment7. Cytokines and Chemokines in Tumorigenesis and Their Pro-tumorigenic and Anti-tumorigenic Roles in Cancer Development8. Role of Proinflammatory Chemokines and cytokines in Tumor growth and metastasis9. The role of Cancer-Associated Fibroblasts in Inflammation of Cancer10. Role of Macrophages in Regulating Tumour Angiogenesis: Implications for Cancer Therapy11. Cancer stem cell signaling and inflammation12. Tumour Microenvironment and Inflammation13. Tumour Infiltrating Lymphocytes as Possible Therapeutic Targets14. Mechanisms of Immune Exhaustion in Cancer: Key Players and Critical Pathways15. Modulation of Tumor Immunogenicity in cancer prevention and therapy16. Immune Forces Impacting DNA-Based Cancer Immunotherapeutic Strategy17. lncRNAs as potential modulators for outcomes of immunotherapy in bladder cancer, a comprehensive review18. Epigenetic Signaling: Regulation of Inflammation in Cancer19. Gut microbiome and epigenetic changes in developing inflammation and cancer20. Interplay of the human microbiome, inflammation and colorectal cancer: Emerging insights and therapeutic prospects21. Metagenomic and Meta-transcriptomic landscapes in cancer22. The Inflammatory Landscape of Gynecological Cancers: Pathophysiology, Risk, and Therapeutic Potential23. The Dual Role of Inflammation in Lung Cancer: Regulation of Tumor Growth via MAPK Pathway24. Chemopreventive Strategies for Inflammation-Related Carcinogenesis: Current Status and Future Direction25. Toxicological Responses to Carcinogens: How Inflammation Plays a Dual Role in Cancer Progression26. Personalized Cancer Treatment: Theranostic and Immunotherapeutic-Based Approaches