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      1. Medicin
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      Natural Product Drug Discovery

      Highly Anticipated Natural Molecules

      AvNing Li,Yang Liu

      Häftad, Engelska, 2026

      Del i serien Drug Discovery Opinions

      2 029 kr

      Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

      Beskrivning

      Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter, written by leading experts, offers insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies.

      It will serve as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. Readers will find the necessary information to navigate the complexities of the field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.

      • Provides a comprehensive analysis of natural products' chemical properties and biological activities for informed drug development
      • Explores challenges and solutions in the commercialization of highly active natural molecules
      • Features expert contributions that offer insights into structural modification and green biomanufacturing strategies
      • Includes case studies that illustrate successful applications of natural products in therapeutic contexts
      • Serves as an essential resource for researchers and professionals in natural product drug discovery and pharmacotherapy

      Produktinformation

      • Utgivningsdatum:2026-02-05
      • Mått:216 x 276 x undefined mm
      • Vikt:1 260 g
      • Format:Häftad
      • Språk:Engelska
      • Serie:Drug Discovery Opinions
      • Antal sidor:472
      • Förlag:Elsevier Science
      • ISBN:9780443405785

      Utforska kategorier

      • Farmakologi inom Medicin
      • Tillverkningsteknik inom Naturvetenskap och teknik

      Mer om författaren

      Professor Ning Li is the associate dean of Chinese Materia Medica of Shenyang Pharmaceutical University, the "Youth talent" of Liao Ning Revitalization Talents Program, the "Talent of Hundred level" of Liaoning Bai Qian Wan Talents Program, the "Leading talent" of both Shenyang High-Level Talent Program and Xinjiang Uygur Autonomous Region. She has focused on the research of chemoprevention of critical diseases, especially the neurodegenerative disease and cancer, through post-transcriptional mechanism on the perspective view of ‘preventive treatment strategy’ of the Traditional Chinese theory. She has hosted seven projects of National Natural Science Foundation of China and published more than 120 SCI papers on famous academic journals, born several prizes like the "First Prize of Provincial Science and technology progress award", and obtained the authorization of 20 invention patents. Professor Yang Liu, currently serves as the Dean of the School of Pharmaceutical Engineering, the Chairman of the Pharmaceutical Engineering Discipline and the Chairman of the Biology and Medicine Discipline at Shenyang Pharmaceutical University, P. R. China. He received his Bachelor and Master Degrees from Hunan University, and Doctoral Degree from Shenyang Pharmaceutical University. Professor Liu has been engaged in innovative research of medicinal chemistry for a long time, leading his group to carry out researches on innovative drugs and modified new drugs for treatment of malignant tumors, diabetes, AD and other major diseases, developing drug preparation technologies suitable for industrial production, and promoting the industrialization of project implementation. He has published over 120 research papers, authored 8 books, and applied for 18 invention patents. He has been selected into the Outstanding Young Scholars in Liaoning Province and the Innovative Talents in Liaoning Province, and has won the first prize for science and technology progresses in Liaoning Province.

      Innehållsförteckning

      • 1. Highly Anticipated Natural Molecules2. The Key Technology in Drug Discovery: Structural Modification of Natural Products3. Naturally Sourced Sodium-Glucose Co-transporter 2 Inhibitors for Hypoglycemic: From Phlorizin to Dapagliflozin4. Polysaccharides from TCM as an Important Resource of New Drugs for Antiosteoporosis and Neurodegenerative Diseases5. Drug Discovery from Daphnane-type Diterpenoids: A Balance Between the Anti-HIV Effect and Toxicity6. The Promising Future of Sesquiterpenoids: A Potential Source of New Drugs7. Tussilagone as a Potential Therapeutic Candidate Against Inflammation-Related Diseases8. Right Time for Drug Development from Volatile Oils9. Natural Products in Alzheimer's Disease10. The Discovery, Synthesis, and Bioactivities of Marine Sesquiterpene Hydroquinones/Quinones11. Cardiac Glycoside: A Potential Antineoplastic Candidate from a Medication of Heart Failure and Atrial Arrhythmia12. Natural Products as Potential Neuroprotective Agents for Ischemic Stroke13. Key Strategy for Drug Development: Green Biomanufacturing of Active Natural Products14. Research and Development of the Anti-Tumor Star Molecule Taxol15. Bile Acids: Dual Facets as Modulators and Targets in Natural Product Drug Discovery16. Natural Cephalotane Alkaloids from Cephalotaxaceae as a Source of New Anticancer Drugs17. Computation-Enabled Natural Products Drug Discovery18. Active Metabolites Derived from Microorganisms of Extreme Environments
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