Hydrophilic-Lipophilic Deviation in Formulation Science and Technology: Principles, Methods, and Applications of HLD offers an in-depth examination of the Hydrophilic-Lipophilic Deviation (HLD) concept as a foundational, quantifiable optimization tool in the formulation science of surfactant, oil, and water systems. It brings together contributions from leading experts to cover the historical development of formulation concepts in the past hundred years, from the Bancroft rule, Winsor R, Beerbover CER, Israelachvili intermolecular packing, Griffin HLB and Shinoda PIT through to the advanced HLD multivariable framework, as a way to select an appropriate multi surrogate expression. It provides a deep dive into critical topics such as surfactant and oil characterization, macro-/micro-/nano-emulsion formulation and properties, particularly interfacial rheology. It also deals with practical applications such as detergency, enhanced oil recovery (EOR), demulsification, asphaltic emulsions, food processing and distribution, cosmetics and medical preparations, and other consumer or industrial products. Each chapter combines theoretical foundations with practical insights, including mistakes and confusions, supported by case studies and recent research findings. The structured approach facilitates a comprehensive understanding the meaning of HLD and its impact on formulation science in various sectors including academia and industry.
This book will address the challenges faced by practitioners in designing and optimizing formulations, ultimately enhancing product performance in interfacial tension, solubilization, time stability and fluid properties.
Hydrophilic-Lipophilic Deviation in Formulation Science and Technology: Principles, Methods, and Applications of HLD is written primarily for advanced researchers, scientists, and engineers specializing in formulation science, colloid and interface science, surfactant chemistry, and chemical engineering.
- Introduces the HLD multivariable concept to solve complex formulation problems, enabling accurate prediction of phase behavior and emulsion properties
- Provides in-depth explanation of HLD equations and their practical application in various systems
- Gives the reader guidance on characterizing surfactants and oils using PACN and EACN concepts
- Offers insight into formulation maps for designing stable or unstable emulsion types across different industries
- Outlines strategies to optimize the solubilization of oils in monophasic WIV systems
- Co-Edited by Jean-Louis Salager, a pioneer in surfactant-oil-water systems and formulation science research for more than half a century
