Prof. Sengottayan Senthil-Nathan is the Head of the Biopesticides and Environmental Toxicology Division at Manonmaniam Sundaranar University and a Professor of Toxicology at Sri Paramakalyani Centre for Excellence in Environmental Science in Tamil Nadu, India. With more than twenty years of experience in natural pesticide research and crop protection, his work focuses on climate change mitigation, agricultural entomology, and biological pest management within sustainable agricultural systems. He has shared his expertise through international conferences and serves on review panels for major research funding agencies. His research on botanically derived bioactive compounds and plant defence mechanisms has significantly contributed to the development of effective biopesticides strategies for sustainable agriculture, and he also holds editorial roles in several international journals.Dr. Prabhakaran Vasantha-Srinivasan is a senior researcher at Chonnam National University in South Korea. His primary research interests include biopesticides and environmental toxicology. Previously, he served as an Assistant Professor and Head of the Department of Biotechnology at St. Peter's Institute of Higher Education and Research in Chennai, Tamil Nadu, India. He completed his Master’s degree in Biomedical genetics at Vellore institute of Technology, and Doctoral degree in Environmental sciences at Manonmaniam Sundaranar University. Dr. Vasantha-Srinivasan boasts over six years of research experience and four years of academic experience. His research endeavours have culminated in more than 60 international publications, with a total h-index of 29. Additionally, he has over two years of international research experience and received a major research grant from the Early Career Research Award by DST-SERB for the years 2016-2018. He has served as a special issue editorial board member for international journals such as Vaccines, natural Pesticides Research, and Physiological and Molecular Plant Pathology.Dr. Sudisha Jogaiah is a Fellow of the National Academy of Sciences (FNASc), the Agricultural Sciences (FNAAS), and the National Academy of Biological Sciences (FNABS). He is also a Bridge Fellow, Government of Japan, and serves as a Visiting Professor at Yamaguchi University, Japan, and Nanjing Agricultural University, China. In 2022, he joined the Department of Environmental Science at the Central University of Kerala as an Associate Professor. He has been listed among the World's Top 2% of Scientists by Stanford University for 3 consecutive years. His research interests include plant pathology, plant–microbe interactions, plant defense signaling, biocontrol agents, biogenic nanoparticles for induced resistance in plants, and bioremediation. The technological quality and scientific rigor of his laboratory are evident from his extensive publication record and the prestigious national and international awards received.

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• 1. Introduction to Integrated Crop Protection2. Molecular Mechanisms and Data-Driven Insights3. Enhancing Pathogen Resistance through Precision Strategies4. Smart Pest Management and Herbivore Defense5. Integrating Environmental Stress Tolerance with Precision Agriculture6. Advanced Biotechnological and Digital Approaches7. Practical Applications in Precision Crop Management8. Challenges and Future Directions: From PISR to Smart Agriculture9. Policy, Regulation, and the Future of Integrated Crop Protection10. Conclusion: Charting the Future of Sustainable, Data-Driven Agriculture