Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms

Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms offers the latest insights into ESKAPE pathogen biofilms, including their formation, structure, and resistance mechanisms and highlights innovative therapeutic strategies to combat them, with a specific focus on combinatorial enzyme therapies. The book begins with an overview of the significant burden these pathogens impose across healthcare and the food industry, laying the groundwork for understanding the intricate relationship between antibiotic resistance and biofilm dynamics. It advocates novel approaches through combinatorial enzymatic therapy, detailing the mechanisms and synergies of various enzymes in effectively dismantling biofilms. With insights into cutting-edge delivery systems, including nanotechnology and the integration of CRISPR-Cas systems and artificial intelligence, the book charts a course for the future of advanced therapeutic strategies. It concludes by addressing regulatory considerations, positioning combinatorial enzyme therapy as a promising frontier in the fight against persistent infections caused by ESKAPE pathogens

• Provides a comprehensive understanding of the mechanisms behind biofilm formation and its role in antimicrobial resistance in ESKAPE pathogens
• Explores actionable strategies through combinatorial enzyme therapies, offering novel tools to dismantle biofilm matrices and enhance treatment outcomes
• Bridges the gap between research and clinical application by delivering practical insights that enable the adoption of enzyme-based solutions in real-world scenarios