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Awanish Kumar, Aditya Upadhyay - Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms, Häftad

Häftad, Engelska, 2027

Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms

Av Awanish Kumar, Aditya Upadhyay

Del i serien Developments in Applied Microbiology and Biotechnology

2491 kr

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Beskrivning
Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms offers the latest insights into ESKAPE pathogen biofilms, including their formation, structure, and resistance mechanisms. In addition, the book highlights innovative therapeutic strategies to combat them, with a specific focus on combinatorial enzyme therapies. It begins with an overview of the significant burden these pathogens impose across healthcare and the food industry, laying the groundwork for understanding the intricate relationship between antibiotic resistance and biofilm dynamics. The book advocates for novel approaches through combinatorial enzymatic therapy, detailing the mechanisms and synergies of various enzymes in effectively dismantling biofilms.

With insights into cutting-edge delivery systems, including nanotechnology and the integration of CRISPR-Cas systems and artificial intelligence, the book charts a course for the future of advanced therapeutic strategies. It concludes by addressing regulatory considerations, positioning combinatorial enzyme therapy as a promising frontier in the fight against persistent infections caused by ESKAPE pathogens.

  • Provides a comprehensive understanding of the mechanisms behind biofilm formation and its role in antimicrobial resistance in ESKAPE pathogens
  • Explores actionable strategies through combinatorial enzyme therapies, offering novel tools to dismantle biofilm matrices and enhance treatment outcomes
  • Bridges the gap between research and clinical application by delivering practical insights that enable the adoption of enzyme-based solutions in real-world scenarios
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Dr. Awanish Kumar is an Associate Professor of the Department of Biotechnology at the National Institute of Technology, Raipur, Chhattisgarh, India. He has more than 13 years of research experience. He received his PhD in molecular parasitology from the CSIR-Central Drug Research Institute, Lucknow, India, and Jawaharlal Nehru University, Delhi, India, and completed his postdoctoral studies at McGill University, Montreal, Canada. His research interests are infection biology, drug targeting, and drug discovery. Aditya Upadhyay is a researcher at the Department of Biotechnology, National Institute of Technology in Raipur, India. His research focuses on infection biology, antibiotic resistance, and drug discovery in relation to biofilm formation. He holds a PhD in Biotechnology from the National Institute of Technology in Raipur, Master of Technology degree in Biotechnology (Honors) from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India and a Bachelor of Technology in Biotechnology from Dr. A.P.J Abdul Kalam Technical University, Lucknow, India. Aditya is currently working on the design of new drugs and therapies to treat salmonella biofilm infections and combat antibiotic resistance. He has published articles in various SCI journals and contributed book chapters.

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