RNA-Binding Proteins Part A

After completing studies for the A.B., A.M., and Ph.D. degrees in chemistry at Harvard University, David W. Christianson joined the faculty of the University of Pennsylvania, where he is currently the Roy and Diana Vagelos Professor in Chemistry and Chemical Biology. At Penn, Christianson’s research focuses on the structural and chemical biology of the zinc-dependent histone deacetylases as well as enzymes of terpene biosynthesis. His research accomplishments have been recognized by several awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, a Guggenheim Fellowship, and the Elizabeth S. and Richard M. Cashin Fellowship from the Radcliffe Institute for Advanced Study at Harvard University. Christianson is also a dedicated classroom teacher, and his accomplishments in this regard have been recognized by the Lindback Award for Distinguished Teaching at Penn and a Rhodes Trust Inspirational Educator Award from Oxford University. Christianson has also held visiting professorships in the Department of Biochemistry at Cambridge University and the Department of Chemistry and Chemical Biology at Harvard University. Christianson has served with Prof. Anna Pyle as Co-Editor-in-Chief of Methods in Enzymology since 2015.Dr. Karen N. Allen works at the Department of Chemistry of the Boston University, the Metcalf Center for Science and Engineering Subashchandrabose Chinnathambi is Additional Professor at the Department of Neurochemistry, National Institute of Mental Health and Neurosciences Hospital Bangalore, Karnataka, India. His scientific interests include physiopathology of neurodegenerative disorders, Tau Cytoskeleton, Tau-GPCR, purinergic and chemokine receptors, Tau stem cells, animal models, neuropharmacology, therapeutic approaches targeting Tau oligomers, and biomarkers for neurodegeneration. He serves on the editorial board for various international cell biology journals and is also a regular invited speaker at a number of meetings and workshops. Dr. Chinnathambi has more than 16 years of research experience in the area of neuroscience and Tau-related research in Alzheimer’s Disease.

• 1. Analysis of the dynamics of RNA-binding proteins in neuronal stress granules by quantitative live cell imagingRoland Brandt2. Quantitative Analysis of A-to-I Editing and Hyper-editing in Human and Mouse DataQuentin Vicens, Mary Ifeoluwa Adesina, Kent Riemondy, Beat Vögeli and Parker Nichols3. Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase SeparationTobias Madl4. RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicingYukio Kawahara5. RNA-binding proteins in synaptic plasticitySourav Banerjee6. CPEB4-repressor complex-mediated mRNA degradationGeorg Stoecklin7. Factors governing the binding affinity of protein-RNA complexes and their mutants analysis and predictionM. Michael Gromiha8. CX3CR1-mediated extracellular Tau internalization and phagosomal proteins in iPSC-derived microgliaSubashchandrabose Chinnathambi, Vaishnavi Ananthanaraya and Tanu Suma Narayanappa9. RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sitesAnshumali Mittal10. Experimental Strategies for Studying RNA-Binding Proteins and Their Complexes in Alternative mRNA SplicingAshish Misra11. Differential conformational dynamics in two type-A RNA-binding domains drive the double-stranded RNA recognition and bindingJeetender Chugh12. Modelling pathophysiological functions of TDP-43 protein in C. elegansGhulam Jeelani Pir13. Biophysical Characterization of alpha-synuclein phase separation in vitroSamir K. Maji14. Design, generation and analysis of RNA substrates for biochemical deconstruction of histone mRNA decaySutapa Chakrabarti and Alexandrina Machado de Amorim15. Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic developmentMainak Bose16. RNA Aptamers Rescue Mitochondrial Dysfunction in Huntington’s DiseaseIpsita Roy and Prajjwal Kushwaha17. An in vitro quantitative PCR based technique for accurate measurement of RNA cap statusChandrama Mukherjee and Avik Mukherjee18. Liquid-liquid phase separation (LLPS) of proteins and RNA moleculesKanchan Garai19. Emerging role of circular RNAs in pancreatic β cellsAmaresh Chandra Panda20. MicroRNAs from extracellular vesicles as a signature for Parkinson's diseaseKatrin Marcus-Alic21. The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless OrganellesMaria Hondele