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David Christianson, Karen N. Allen - Structure, Function, and Regulation of G Protein-Coupled Receptors Part A, Inbunden

Inbunden, Engelska, 2027

Structure, Function, and Regulation of G Protein-Coupled Receptors Part A

Av David Christianson, Karen N. Allen

Del 748 i serien Methods in Enzymology

2240 kr

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Beskrivning
G protein-coupled receptors constitute one of the largest classes of cell surface receptors in the human genome and drug targets for approximately one third of the currently prescribed medicines. The has been a tremendous advance in understanding the activation, signaling, and regulation of these receptors over the past couple of years using cellular, biochemical, structural, and pharmacological approaches. These two volumes of Methods in Enzymology cover these recent advances in the form of short overview of the key topics as well as step-by-step protocols developed to probe the functional attributes of these versatile receptors.

  • Contributions by the leaders in the field of GPCR biology
  • Focus on recently developed and broadly applicable methods and advances
  • Chapters are based on most recent advances in the field with futuristic outlook
Produktinformation
  • Utgivningsdatum: 2027-05-01
  • Mått: 152 x 229 x undefined mm
  • Format: Inbunden
  • Språk: Engelska
  • Serie: Methods in Enzymology
  • Antal sidor: 258
  • Förlag: Elsevier Science
  • Medarbetare: Arun K. Shukla
  • ISBN: 9780443521829
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Mer om författaren

After completing studies for the A.B., A.M., and Ph.D. degrees in chemistry at Harvard University, David W. Christianson joined the faculty of the University of Pennsylvania, where he is currently the Roy and Diana Vagelos Professor in Chemistry and Chemical Biology. At Penn, Christianson’s research focuses on the structural and chemical biology of the zinc-dependent histone deacetylases as well as enzymes of terpene biosynthesis. His research accomplishments have been recognized by several awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, a Guggenheim Fellowship, and the Elizabeth S. and Richard M. Cashin Fellowship from the Radcliffe Institute for Advanced Study at Harvard University. Christianson is also a dedicated classroom teacher, and his accomplishments in this regard have been recognized by the Lindback Award for Distinguished Teaching at Penn and a Rhodes Trust Inspirational Educator Award from Oxford University. Christianson has also held visiting professorships in the Department of Biochemistry at Cambridge University and the Department of Chemistry and Chemical Biology at Harvard University. Christianson has served with Prof. Anna Pyle as Co-Editor-in-Chief of Methods in Enzymology since 2015.Dr. Karen N. Allen works at the Department of Chemistry of the Boston University, the Metcalf Center for Science and Engineering Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

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