Robert Kushner, Professor of Medicine, Northwestern University FeinbergSchool of Medicine, Chicago, USAVictor Lawrence, Consultant Physician, Endocrinology and Diabetes,St Mary’s Hospital, Newport, Isle of Wight, UKSudhesh Kumar, Professor of Medicine, Warwick Medical School,University of Warwick, UK

"Written by experts in the field of obesity, this book covers an extremely important topic and all clinicians would benefit from reading it. Many health conditions can be linked to obesity, and many diseases are worsened by obesity.  Teaching medical students, residents, and clinicians to treat and manage obesity is essential to the health of the world.”  (Doody’s, 25 April 2014)

• Preface viiPart 1 The Biology of Obesity—Why It Occurs 1Victor Lawrence, Section Editor1 Energy Balance and Body Weight Homeostasis 32 The Genetic Basis of Obesity 133 Adipocyte Biology 254 Fetal and Infant Origins of Obesity 335 Metabolic Fuels and Obesity 41Part 2 Clinical Management of the Obese Individual 51Robert Kushner, Section Editor6 Practical Guide to Clinical Assessment and Treatment Planning 537 Stages of Obesity and Weight Maintenanc 638 Dietary Management 719 Physical Activity and Exercise 8110 Behavior Therapy 9111 Pharmacotherapy 9912 Surgery 109Part 3 Clinical Management of Obesity-Related Co-morbidities 121Sudhesh Kumar and Milan K. Piya, Section Editors13 Diabetes and Metabolic Diseases 12314 Obesity and Reproductive Health 13315 Gastro-intestinal and Hepatobiliary Disease 14116 Respiratory Disease 14917 Obesity and Cardiovascular Disease 15718 Obesity: Mental Health and Social Consequences 16719 Obesity and Musculo-skeletal Disease 17520 The Obese Patient in Hospital 181Conversion Table 187Index 189

Robert Kushner, Professor of Medicine, Northwestern University FeinbergSchool of Medicine, Chicago, USAVictor Lawrence, Consultant Physician, Endocrinology and Diabetes,St Mary’s Hospital, Newport, Isle of Wight, UKSudhesh Kumar, Professor of Medicine, Warwick Medical School,University of Warwick, UK

"Written by experts in the field of obesity, this book covers an extremely important topic and all clinicians would benefit from reading it. Many health conditions can be linked to obesity, and many diseases are worsened by obesity.  Teaching medical students, residents, and clinicians to treat and manage obesity is essential to the health of the world.”  (Doody’s, 25 April 2014)

• Preface viiPart 1 The Biology of Obesity—Why It Occurs 1Victor Lawrence, Section Editor1 Energy Balance and Body Weight Homeostasis 32 The Genetic Basis of Obesity 133 Adipocyte Biology 254 Fetal and Infant Origins of Obesity 335 Metabolic Fuels and Obesity 41Part 2 Clinical Management of the Obese Individual 51Robert Kushner, Section Editor6 Practical Guide to Clinical Assessment and Treatment Planning 537 Stages of Obesity and Weight Maintenanc 638 Dietary Management 719 Physical Activity and Exercise 8110 Behavior Therapy 9111 Pharmacotherapy 9912 Surgery 109Part 3 Clinical Management of Obesity-Related Co-morbidities 121Sudhesh Kumar and Milan K. Piya, Section Editors13 Diabetes and Metabolic Diseases 12314 Obesity and Reproductive Health 13315 Gastro-intestinal and Hepatobiliary Disease 14116 Respiratory Disease 14917 Obesity and Cardiovascular Disease 15718 Obesity: Mental Health and Social Consequences 16719 Obesity and Musculo-skeletal Disease 17520 The Obese Patient in Hospital 181Conversion Table 187Index 189

Robert Kushner, Professor of Medicine, Northwestern University FeinbergSchool of Medicine, Chicago, USAVictor Lawrence, Consultant Physician, Endocrinology and Diabetes,St Mary’s Hospital, Newport, Isle of Wight, UKSudhesh Kumar, Professor of Medicine, Warwick Medical School,University of Warwick, UK

"Written by experts in the field of obesity, this book covers an extremely important topic and all clinicians would benefit from reading it. Many health conditions can be linked to obesity, and many diseases are worsened by obesity.  Teaching medical students, residents, and clinicians to treat and manage obesity is essential to the health of the world.”  (Doody’s, 25 April 2014)

• Preface viiPart 1 The Biology of Obesity—Why It Occurs 1Victor Lawrence, Section Editor1 Energy Balance and Body Weight Homeostasis 32 The Genetic Basis of Obesity 133 Adipocyte Biology 254 Fetal and Infant Origins of Obesity 335 Metabolic Fuels and Obesity 41Part 2 Clinical Management of the Obese Individual 51Robert Kushner, Section Editor6 Practical Guide to Clinical Assessment and Treatment Planning 537 Stages of Obesity and Weight Maintenanc 638 Dietary Management 719 Physical Activity and Exercise 8110 Behavior Therapy 9111 Pharmacotherapy 9912 Surgery 109Part 3 Clinical Management of Obesity-Related Co-morbidities 121Sudhesh Kumar and Milan K. Piya, Section Editors13 Diabetes and Metabolic Diseases 12314 Obesity and Reproductive Health 13315 Gastro-intestinal and Hepatobiliary Disease 14116 Respiratory Disease 14917 Obesity and Cardiovascular Disease 15718 Obesity: Mental Health and Social Consequences 16719 Obesity and Musculo-skeletal Disease 17520 The Obese Patient in Hospital 181Conversion Table 187Index 189